CMap Candidate Details

Structure:
CMap ID: C09998
Pert ID: BRD-K24050847
Compound Name: KIN001-270
Targets: --
MoA: --
SMILES: CC1=C(C=C(C=C1)NC2=NC=NC(=C2)C3=CC(=CC=C3)N4C(=O)C5=CC=CC=C5C4=O)NS(=O)(=O)C
InchiKey: CKUFOBCNTCLXJP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92872 BRD-K24050847 A375 0.04 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
92899 BRD-K24050847 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92938 BRD-K24050847 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93002 BRD-K24050847 CD34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93045 BRD-K24050847 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
93090 BRD-K24050847 HEK293 1.11 uM 24 h 0.32 1.33 0.84 0.33 1.17 0.93
93132 BRD-K24050847 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93175 BRD-K24050847 HEPG2 0.12 uM 24 h -0.26 -1.09 0.33 0.0 0.0 0.0
93228 BRD-K24050847 HUVEC 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93282 BRD-K24050847 JURKAT 10 uM 24 h 0.27 1.11 0.25 -0.27 -0.91 0.3
93320 BRD-K24050847 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93363 BRD-K24050847 MDAMB231 0.12 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
93420 BRD-K24050847 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93449 BRD-K24050847 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93489 BRD-K24050847 SKL 10 uM 24 h 0.24 1.01 0.12 0.28 1.0 0.42
93548 BRD-K24050847 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
93588 BRD-K24050847 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).