Investigational Drug Details
| Drug ID: | D104 |
| Drug Name: | Delta-tocotrienol |
| Synonyms: | -- |
| Type: | Chemical drug |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | 5282350 |
| CasNo: | 25612-59-3 |
| Repositioning for NAFLD: | No |
| SMILES: | Cc1c2c(CC[C@](O2)(CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)C)cc(c1)O |
| Structure: |
|
| InChiKey: | ODADKLYLWWCHNB-LDYBVBFYSA-N |
| Molecular Weight: | 396.615 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 2 on-going (SLCTR/2019/038) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0725 | SLCTR/2019/038 | Phase 2 | Not Recruiting | No Results Available | 16/10/2019 | 7 February 2022 | Details |
| L0863 | SLCTR/2015/023 | Phase 2 | Recruiting | No Results Available | 03/10/2015 | 7 February 2022 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A06255 | 32951743 | Complement Ther Med | Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial. | Details |
| A13800 | 29749323 | Turk J Gastroenterol | Effects of Delta-tocotrienol Supplementation on Liver Enzymes, Inflammation, Oxidative stress and Hepatic Steatosis in Patients with Nonalcoholic Fatty Liver Disease. | Details |
| A15588 | 28825992 | J Nutr Biochem | Effects of delta-tocotrienol on obesity-related adipocyte hypertrophy, inflammation and hepatic steatosis in high-fat-fed mice. | Details |