Investigational Drug Details
| Drug ID: | D111 |
| Drug Name: | Digestive enzymes |
| Synonyms: | Digestive enzyme |
| Type: | Supplement |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | -- |
| CasNo: | -- |
| Repositioning for NAFLD: | No |
| SMILES: | -- |
| InChiKey: | -- |
| Molecular Weight: | -- |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 2 on-going (JPRN-UMIN000017266) |
| Latest Progress: | Under clinical trials |

| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0877 | JPRN-UMIN000017266 | Phase 2 | Recruiting | No Results Available | 24/04/2015 | 2 April 2019 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A06328 | 32927075 | J Am Coll Surg | Preventive Effect of High-Dose Digestive Enzyme Management on Development of Nonalcoholic Fatty Liver Disease after Pancreaticoduodenectomy: A Randomized Controlled Clinical Trial. | Details |
| A08597 | 32045507 | Mol Nutr Food Res | Lactose, Maltose, and Sucrose in Health and Disease. | Details |
| A16370 | 28432400 | Internist (Berl) | [The intestinal microbiome and metabolic diseases : From obesity to diabetes and nonalcoholic steatohepatitis]. | Details |
| A16746 | 28212301 | Mar Drugs | The Phytocomplex from Fucus vesiculosus and Ascophyllum nodosum Controls Postprandial Plasma Glucose Levels: An In Vitro and In Vivo Study in a Mouse Model of NASH. | Details |
| A28537 | 11907349 | J Clin Gastroenterol | Intestinal permeation and gastrointestinal disease. | Details |
| A50462 | 35381910 | Surg Case Rep | Nonalcoholic fatty liver disease developed after pancreatoduodenectomy for solid pseudopapillary neoplasm in a 10-year-old girl: a case report. | Details |
| A52757 | 22405696 | J Nutr Biochem | Perinatal undernutrition alters intestinal alkaline phosphatase and its main transcription factors KLF4 and Cdx1 in adult offspring fed a high-fat diet. | Details |