Investigational Drug Details
| Drug ID: | D135 |
| Drug Name: | Fenugreek |
| Synonyms: | Trigonella Foenum-graecum Seed Extract |
| Type: | Biological extract |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | -- |
| CasNo: | 8016-13-5 |
| Repositioning for NAFLD: | No |
| SMILES: | O1[C@@H]2[C@@H]([C@@]3([C@H]([C@H]4[C@@H]([C@@]5([C@@H](CC4)C[C@@H](O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)C5)C)CC3)C2)C)[C@@H]([C@@]1(O)CC[C@H](CO[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)CO)C)C |
| Structure: |
|
| InChiKey: | TVNGRDSDHVARNR-SYQAKRSCSA-N |
| Molecular Weight: | 907.057 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 2&3 completed (NCT02303314) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0894 | IRCT2013102015083N1 | Phase 2/Phase 3 | Not Recruiting | No Results Available | 01/09/2014 | 22 February 2018 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A07255 | 32565595 | Indian J Pharmacol | Comparison of the efficacy of oral fenugreek seeds hydroalcoholic extract versus placebo in nonalcoholic fatty liver disease; a randomized, triple-blind controlled pilot clinical trial. | Details |
| A14840 | 29209440 | EPMA J | Efficacy of Fenugreek-based bionanocomposite on renal dysfunction and endogenous intoxication in high-calorie diet-induced obesity rat model-comparative study. | Details |
| A20877 | 25670619 | Arab J Gastroenterol | Effects of fenugreek, Nigella, and termis seeds in nonalcoholic fatty liver in obese diabetic albino rats. | Details |
| A47314 | 17453353 | Cell Biol Toxicol | Fenugreek seed (Trigonella foenum graecum) polyphenols inhibit ethanol-induced collagen and lipid accumulation in rat liver. | Details |