Investigational Drug Details
| Drug ID: | D148 |
| Drug Name: | GB1211 |
| Synonyms: | -- |
| Type: | Chemical drug |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | 132201704 |
| CasNo: | -- |
| Repositioning for NAFLD: | No |
| SMILES: | C1=C(C=C(C(=C1F)F)F)C2=CN(N=N2)C3C(C(OC(C3O)SC4=CC(=CN=C4)Br)CO)O |
| Structure: |
|
| InChiKey: | FNCLKJPMEFPXOR-UHFFFAOYSA-N |
| Molecular Weight: | 533.3 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | Gelactin-3 inhibitor |
| Therapeutic Category: | Anti-fibrosis |
| Clinical Trial Progress: | Phase 1 completed (NCT03809052) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0328 | NCT04607655 | Phase 1/Phase 2 | Withdrawn | No Results Available | March 2021 | February 4, 2021 | Details |
| L0778 | NCT03809052 | Phase 1 | Recruiting | No Results Available | 07/12/2018 | 12 December 2020 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs | |
|---|---|---|---|---|---|
| S03 | Anti-fibrosis | fibrosis | Angiotensin Receptor Blocker (ARB); CCR2/CCR5 antagonist; Thyroid receptor β agonist; PEGylated human FGF21 analogue; Monoclonal antibody to lysyl oxidase-like 2 (LOXL2); Galectin-3 inhibitor; FGF19 variant | Losartan; Cenicriviroc; VK-2809; MGL-3196; Pegbelfermin; Simtuzumab; GR-MD-02; NGM282 | Details |
| Article ID | PMID | Source | Title |
|---|