Investigational Drug Details
| Drug ID: | D206 |
| Drug Name: | Lingguizhugan decoction |
| Synonyms: | Fulin, Guizhi, Baizhu, Gancao |
| Type: | Traditional medicine |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | -- |
| CasNo: | -- |
| Repositioning for NAFLD: | No |
| SMILES: | -- |
| InChiKey: | -- |
| Molecular Weight: | -- |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Clinical trial on-going (ChiCTR1800014364) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0801 | ChiCTR1800014364 | Post-market | Not Recruiting | No Results Available | 08/01/2018 | 31 July 2018 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A00738 | 34983596 | Chin Med | Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages. | Details |
| A07375 | 32522273 | Trials | Traditional Chinese medicine Lingguizhugan decoction treating non-alcoholic fatty liver disease with spleen-yang deficiency pattern: Study protocol for a multicenter randomized controlled trial. | Details |
| A10373 | 31367159 | World J Gastroenterol | Lingguizhugan decoction attenuates diet-induced obesity and hepatosteatosis via gut microbiota. | Details |
| A14325 | 29464180 | Int J Genomics | Lingguizhugan Decoction Protects against High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease by Alleviating Oxidative Stress and Activating Cholesterol Secretion. | Details |
| A14989 | 29137289 | Oncotarget | Lingguizhugan decoction improves non-alcoholic fatty liver disease by altering insulin resistance and lipid metabolism related genes: a whole trancriptome study by RNA-Seq. | Details |
| A28698 | 35116066 | Evid Based Complement Alternat Med | Evaluation of the Mechanism of Modified Lingguizhugan Decoction in the Treatment of Nonalcoholic Fatty Liver Disease. | Details |
| A50214 | 35471471 | Front Med | Lingguizhugan Decoction, a Chinese herbal formula, improves insulin resistance in overweight/obese subjects with non-alcoholic fatty liver disease: a translational approach. | Details |