Investigational Drug Details
| Drug ID: | D272 |
| Drug Name: | Phlebotomy |
| Synonyms: | -- |
| Type: | Miscellany |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | -- |
| CasNo: | -- |
| Repositioning for NAFLD: | No |
| SMILES: | -- |
| InChiKey: | -- |
| Molecular Weight: | -- |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Clinical trial on-going (IRCT20161205031252N4) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0518 | IRCT20161205031252N4 | Not applicable | Not Recruiting | No Results Available | 06/12/2017 | 22 February 2018 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A00912 | 34932603 | PLoS One | Abdominal pain and cirrhosis at diagnosis of hemochromatosis: Analysis of 219 referred probands with HFE p.C282Y homozygosity and a literature review. | Details |
| A06245 | 32952877 | World J Hepatol | Racial disparities in nonalcoholic fatty liver disease clinical trial enrollment: A systematic review and meta-analysis. | Details |
| A08742 | 32003680 | Curr Pharm Des | Dysmetabolic Hyperferritinemia and Dysmetabolic Iron Overload Syndrome (DIOS): Two Related Conditions or Different Entities? | Details |
| A08753 | 32000639 | Curr Pharm Des | Dysmetabolic Iron Overload in Metabolic Syndrome. | Details |
| A10455 | 31330553 | Semin Liver Dis | Hyperferritinemia in Nonalcoholic Fatty Liver Disease: Iron Accumulation or Inflammation? | Details |
| A11729 | 30774269 | World J Gastroenterol | Iron and liver fibrosis: Mechanistic and clinical aspects. | Details |
| A11765 | 30761559 | Aliment Pharmacol Ther | Review article: iron disturbances in chronic liver diseases other than haemochromatosis - pathogenic, prognostic, and therapeutic implications. | Details |
| A16051 | 28593739 | Hepatol Res | Systematic review and meta-analysis to determine the impact of iron depletion in dysmetabolic iron overload syndrome and non-alcoholic fatty liver disease. | Details |
| A16571 | 28299304 | Adv Biomed Res | Effects of Phlebotomy on Liver Enzymes and Histology of Patients with Nonalcoholic Fatty Liver Disease. | Details |
| A16862 | 28123936 | Mol Metab | Metabolomic profiling identifies potential pathways involved in the interaction of iron homeostasis with glucose metabolism. | Details |
| A16974 | 28067690 | J Pediatr Hematol Oncol | Iron Overload in the Liver of 2 Children: Nonalcoholic Steatohepatitis and Juvenile Hemochromatosis. | Details |
| A17129 | 27976635 | Saudi J Gastroenterol | Outcome of phlebotomy for treating nonalcoholic fatty liver disease: A systematic review and meta-analysis. | Details |
| A17963 | 27447538 | Ann N Y Acad Sci | Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice. | Details |
| A18112 | 27346296 | Eur J Intern Med | How should hyperferritinaemia be investigated and managed? | Details |
| A19467 | 26550266 | Int J Clin Exp Med | Prediction of liver injury using the BP-ANN model with metabolic parameters in overweight and obese Chinese subjects. | Details |
| A21133 | 25524401 | Hepatology | The impact of phlebotomy in nonalcoholic fatty liver disease: A prospective, randomized, controlled trial. | Details |
| A21542 | 25241989 | Chin J Physiol | Relationship between hemoglobin levels and risk for suspected non-alcoholic fatty liver in Taiwanese adults. | Details |
| A22193 | 24756010 | Ann Hepatol | Inflammation is not the cause of an elevated serum ferritin in non-alcoholic fatty liver disease. | Details |
| A22326 | 24659891 | World J Gastroenterol | A randomized trial of iron depletion in patients with nonalcoholic fatty liver disease and hyperferritinemia. | Details |
| A22578 | 24447492 | Lipids Health Dis | Fasting time and lipid parameters: association with hepatic steatosis--data from a random population sample. | Details |