Investigational Drug Details
| Drug ID: | D286 |
| Drug Name: | Propolis |
| Synonyms: | -- |
| Type: | Biological extract |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | -- |
| CasNo: | 85665-41-4 |
| Repositioning for NAFLD: | No |
| SMILES: | -- |
| InChiKey: | -- |
| Molecular Weight: | -- |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 3 on-going (IRCT20161023030445N2) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0488 | IRCT20180824040857N1 | Phase 2 | Not Recruiting | No Results Available | 24/10/2018 | 6 October 2020 | Details |
| L0506 | IRCT20161023030445N2 | Phase 3 | Recruiting | No Results Available | 26/03/2018 | 30 April 2018 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A05668 | 33166032 | Phytother Res | Protective effects of propolis on hepatic steatosis and fibrosis among patients with nonalcoholic fatty liver disease (NAFLD) evaluated by real-time two-dimensional shear wave elastography: A randomized clinical trial. | Details |
| A09285 | 31805752 | Molecules | Effects of Propolis Extract and Propolis-Derived Compounds on Obesity and Diabetes: Knowledge from Cellular and Animal Models. | Details |
| A10367 | 31372694 | Naunyn Schmiedebergs Arch Pharmacol | Chrysin ameliorates nonalcoholic fatty liver disease in rats. | Details |
| A16360 | 28437890 | Biomed Pharmacother | Does propolis have any effect on non-alcoholic fatty liver disease? | Details |
| A49732 | 35655096 | Acta Pharmacol Sin | Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity. | Details |
| A51854 | 33652692 | Antioxidants (Basel) | Propolis in Metabolic Syndrome and Its Associated Chronic Diseases: A Narrative Review. | Details |