Investigational Drug Details

Drug ID: D296
Drug Name: Rabeprazol sodium
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Type: Miscellany
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Repositioning for NAFLD: No
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Clinical Trial Progress: Phase 1 completed (NCT03143166: The DE tablet demonstrated BE to the capsule; however, at high gastric pH, BA of the tablet was reduced by approximately 70%, which may lead to reduced efficacy. Data indicate the importance of examining not only BE under standard conditions, but relative BA at elevated gastric pH. Such investigations may avoid the reduced BA at elevated pH that is quite common in the target population (the elderly and/or patients treated with gastric-acid modifying co-medications), and therefore reduce treatment failure with DE.)
Latest Progress: Under clinical trials