Investigational Drug Details
| Drug ID: | D310 |
| Drug Name: | Rosemary |
| Synonyms: | Allergenic Extract- Rosemary Rosmarinus Officinalis; Rosemary Herbs; Rosemary Leaf; Rosemary Leaf Extract; Rosemary, Fresh; Rosemary,dried; Rosemary,fresh; Rosmarini Folium; Rosmarinus Officinalis (Rosemary) Extract; Rosmarinus Officinalis (Rosemary) Leaf; Rosmarinus Officinalis (Rosemary) Leaf Extract; Rosmarinus Officinalis (Rosemary) Leaf Powder; Rosmarinus Officinalis Extract; Rosmarinus Officinalis Leaf; Rosmarinus Officinalis Leaf Dry Extract; Rosmarinus Officinalis Leaf Extract; Rosmarinus Officinalis Preparation; Spices, Rosemary, Dried |
| Type: | Biological drug |
| DrugBank ID: | DB14272 |
| DrugBank Description: | Rosemary is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. |
| PubChem ID: | 10253785 |
| CasNo: | 97766-33-1 |
| Repositioning for NAFLD: | No |
| SMILES: | O1[C@@H]([C@@H](O)[C@H](O)[C@@H](O)[C@@H]1Oc1cc(c2oc3c(c(=O)c2)c(O)cc(O)c3)ccc1O)C(=O)O |
| Structure: |
|
| InChiKey: | JDOFZOKGCYYUER-ZFORQUDYSA-N |
| Molecular Weight: | 462.363 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 2 on-going (IRCT20120415009472N20) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0719 | IRCT20120415009472N20 | Phase 2 | Recruiting | No Results Available | 12/11/2019 | 17 December 2019 | Details |
| L0726 | IRCT20120415009472N19 | Phase 2 | Recruiting | No Results Available | 14/10/2019 | 5 November 2019 | Details |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A02306 | 34426744 | Evid Based Complement Alternat Med | Targeting miRNA by Natural Products: A Novel Therapeutic Approach for Nonalcoholic Fatty Liver. | Details |
| A09683 | 31650134 | Food Funct | Regulation effects of rosemary (Rosmarinus officinalis Linn.) on hepatic lipid metabolism in OA induced NAFLD rats. | Details |
| A21401 | 25348739 | J Sci Food Agric | Carnosic acid attenuates obesity-induced glucose intolerance and hepatic fat accumulation by modulating genes of lipid metabolism in C57BL/6J-ob/ob mice. | Details |
| A45821 | 22531045 | Drug Metab Dispos | In vitro hepatotoxicity and cytochrome P450 induction and inhibition characteristics of carnosic acid, a dietary supplement with antiadipogenic properties. | Details |
| A50638 | 35318738 | Phytother Res | Effect of rosemary leaf powder with weight loss diet on lipid profile, glycemic status, and liver enzymes in patients with nonalcoholic fatty liver disease: A randomized, double-blind clinical trial. | Details |