Investigational Drug Details
| Drug ID: | D350 |
| Drug Name: | Stevia |
| Synonyms: | Stevia Dry Leaves |
| Type: | Chemical drug |
| DrugBank ID: | DB15136 |
| DrugBank Description: | Rebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus). |
| PubChem ID: | 6918840 |
| CasNo: | 58543-16-1 |
| Repositioning for NAFLD: | No |
| SMILES: | C[C@]12[C@H]3[C@]4(C[C@@](CC3)(C(=C)C4)O[C@H]3[C@H](O[C@@H]4O[C@H](CO)[C@H]([C@@H]([C@H]4O)O)O)[C@@H](O[C@@H]4O[C@H](CO)[C@H]([C@@H]([C@H]4O)O)O)[C@@H]([C@H](O3)CO)O)CC[C@@H]1[C@@](C(=O)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O)(C)CCC2 |
| Structure: |
|
| InChiKey: | HELXLJCILKEWJH-NCGAPWICSA-N |
| Molecular Weight: | 967.021 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 3 on-going (IRCT20181119041701N1) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0736 | IRCT20181119041701N1 | Phase 3 | Not Recruiting | No Results Available | 05/07/2019 | 26 August 2019 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs | |
|---|---|---|---|---|---|
| S01 | Improve insulin resistance | insulin sensitizer; insulin resistance; glucose tolerance | Biguanide: increases 5-AMP activated protein kinase signaling; SGLT-2 inhibitor; Thiazalidinedione: selective PPAR-γ agonists; GLP-1 agonist | Metformin; Empagliflozin; Canagliflozin; Rosiglitazone; Pioglitazone; Liraglutide | Details |