Investigational Drug Details
| Drug ID: | D373 |
| Drug Name: | Tranilast |
| Synonyms: | N-(3,4-Dimethoxycinnamoyl)anthranilic acid |
| Type: | Chemical drug |
| DrugBank ID: | DB07615 |
| DrugBank Description: | Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. |
| PubChem ID: | 5282230 |
| CasNo: | 53902-12-8 |
| Repositioning for NAFLD: | No |
| SMILES: | N(C(=O)C=Cc1cc(OC)c(cc1)OC)c1c(C(=O)O)cccc1 |
| Structure: |
|
| InChiKey: | NZHGWWWHIYHZNX-UHFFFAOYSA-N |
| Molecular Weight: | 327.336 |
| DrugBank Targets: | Hematopoietic prostaglandin D synthase inhibitor |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. |
| Targets: | HPGDS inhibitor |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Clinical trial on-going (JPRN-UMIN000001670) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0685 | JPRN-UMIN000001670 | Not selected | Not Recruiting | No Results Available | 30/01/2009 | 2 April 2019 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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