Investigational Drug Details
| Drug ID: | D399 |
| Drug Name: | β-glucan |
| Synonyms: | -- |
| Type: | Chemical drug |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | 439262 |
| CasNo: | 9041-22-9 |
| Repositioning for NAFLD: | No |
| SMILES: | -- |
| InChiKey: | -- |
| Molecular Weight: | 504.438 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | Cr3 modulator |
| Therapeutic Category: | Anticancer agent |
| Clinical Trial Progress: | Clinical trial on-going (NCT02178839) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0759 | NCT02178839 | Not applicable | Not recruiting | No Results Available | 18/06/2014 | 19 February 2015 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A00341 | 35127789 | Front Nutr | Lentinan Supplementation Protects the Gut-Liver Axis and Prevents Steatohepatitis: The Role of Gut Microbiota Involved. | Details |
| A01921 | 34561722 | Eur J Nutr | Effects of β-glucan, probiotics, and synbiotics on obesity-associated colitis and hepatic manifestations in C57BL/6J mice. | Details |
| A02509 | 34347479 | J Agric Food Chem | Hepatic Lipidomics Analysis Reveals the Ameliorative Effects of Highland Barley β-Glucan on Western Diet-Induced Nonalcoholic Fatty Liver Disease Mice. | Details |
| A06233 | 32960625 | Nutr Hosp | [Effectiveness of hydroxycinamates and beta-glucans as dietary tools against obesity and its associated dysfunctions, and their application as nutraceuticals]. | Details |
| A15253 | 29023387 | Nutrients | Combination of β-glucan and Morus alba L. Leaf Extract Promotes Metabolic Benefits in Mice Fed a High-Fat Diet. | Details |
| A30275 | 32713066 | J Food Biochem | β-Glucan ameliorates nonalcoholic steatohepatitis induced by methionine and choline-deficient diet in mice. | Details |
| A51922 | 33228176 | Nutrients | Effects of β-glucan Rich Barley Flour on Glucose and Lipid Metabolism in the Ileum, Liver, and Adipose Tissues of High-Fat Diet Induced-Obesity Model Male Mice Analyzed by DNA Microarray. | Details |