Investigational Drug Details
| Drug ID: | D413 |
| Drug Name: | Zhenzhu Tiaozhi Capsule |
| Synonyms: | composed of Ligustri Lucidi Fructus (LLF), Salviae Miltiorrhizae Radix et Rhizoma (SMR), Coptidis Rhizoma (CR),Notoginseng Radix et Rhizoma (NRR), Atractylodis Macrocephalae Rhizoma (AMR), Cirsii Japonici Herba Radix (CJHR), Citri Sarcodactylis Fructus (CSF) and Eucommiae Cortex (EC) |
| Type: | Traditional medicine |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | -- |
| CasNo: | -- |
| Repositioning for NAFLD: | No |
| SMILES: | -- |
| InChiKey: | -- |
| Molecular Weight: | -- |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Clinical trial on-going (NCT03375580) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0806 | NCT03375580 | Not applicable | Recruiting | No Results Available | 26/11/2017 | 8 January 2018 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A04069 | 33771638 | J Ethnopharmacol | Molecular mechanism of Fufang Zhenzhu Tiaozhi capsule in the treatment of type 2 diabetes mellitus with nonalcoholic fatty liver disease based on network pharmacology and validation in minipigs. | Details |
| A42202 | 35247475 | J Ethnopharmacol | The Chinese medicine Fufang Zhenzhu Tiaozhi capsule protects against renal injury and inflammation in mice with diabetic kidney disease. | Details |
| A44372 | 28795381 | Chin J Integr Med | Research progress on prevention and treatment of glucolipid metabolic disease with integrated traditional Chinese and Western medicine. | Details |
| A49338 | 35784533 | Front Endocrinol (Lausanne) | Fufang Zhenzhu Tiaozhi Capsule Prevents Intestinal Inflammation and Barrier Disruption in Mice With Non-Alcoholic Steatohepatitis. | Details |
| A51156 | 35447198 | J Ethnopharmacol | The Chinese medicine Fufang Zhenzhu Tiaozhi capsule protects against atherosclerosis by suppressing EndMT via modulating Akt1/β-catenin signaling pathway. | Details |