Investigational Drug Details
| Drug ID: | D071 |
| Drug Name: | Chicory |
| Synonyms: | Cichorium intybus L. |
| Type: | Biological extract |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | -- |
| CasNo: | 68650-43-1 |
| Repositioning for NAFLD: | No |
| SMILES: | -- |
| InChiKey: | -- |
| Molecular Weight: | -- |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 3 on-going (IRCT20190819044565N2) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0515 | IRCT20171216037911N1 | Not applicable | Not Recruiting | No Results Available | 03/01/2018 | 22 February 2018 | Details |
| L0529 | IRCT201406183664N12 | Phase 2 | Not Recruiting | No Results Available | 18/01/2015 | 22 February 2018 | Details |
| L0712 | IRCT20190819044565N2 | Phase 3 | Recruiting | No Results Available | 24/12/2019 | 13 January 2020 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A04806 | 33498684 | Plants (Basel) | Plants of the Spontaneous Flora with Beneficial Action in the Management of Diabetes, Hepatic Disorders, and Cardiovascular Disease. | Details |
| A11160 | 31017556 | Int J Vitam Nutr Res | Turmeric and chicory seed have beneficial effects on obesity markers and lipid profile in non-alcoholic fatty liver disease (NAFLD). | Details |
| A11896 | 30690116 | Int J Biol Macromol | Untargeted metabonomics reveals intervention effects of chicory polysaccharide in a rat model of non-alcoholic fatty liver disease. | Details |
| A13454 | 29964102 | Int J Biol Macromol | Chicory (Cichorium intybus L.) polysaccharides attenuate high-fat diet induced non-alcoholic fatty liver disease via AMPK activation. | Details |
| A23641 | 23603006 | Food Chem Toxicol | Amelioration by chicory seed extract of diabetes- and oleic acid-induced non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) via modulation of PPARα and SREBP-1. | Details |
| A47357 | 12860315 | J Ethnopharmacol | Antihepatotoxic activity of seeds of Cichorium intybus. | Details |