Investigational Drug Details
| Drug ID: | D086 |
| Drug Name: | Miricorilant |
| Synonyms: | CORT118335 |
| Type: | Chemical drug |
| DrugBank ID: | DB16234 |
| DrugBank Description: | Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent Weight Gain While Taking Antipsychotic Medications (GRATITUDE)). |
| PubChem ID: | 66550324 |
| CasNo: | 1400902-13-7 |
| Repositioning for NAFLD: | No |
| SMILES: | C(c1c([nH]c(=O)[nH]c1=O)[C@H]1CC[C@@H](CC1)c1ccccc1)c1cc(C(F)(F)F)ccc1 |
| Structure: |
|
| InChiKey: | GVVUZBSCYAVFTI-IYARVYRRSA-N |
| Molecular Weight: | 428.454 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | GCR antagonist; MCR antagonist |
| Therapeutic Category: | Hepatoprotectants |
| Clinical Trial Progress: | Phase 1 on-going (NCT05117489); Phase 2 terminated (NCT03823703: Suspended by sponsor, pending investigation of abnormal laboratory values in patients with NASH) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0165 | NCT05117489 | Phase 1 | Recruiting | No Results Available | November 2021 | November 11, 2021 | Details |
| L0166 | NCT03823703 | Phase 2 | Terminated | No Results Available | November 4, 2020 | October 6, 2021 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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| Article ID | PMID | Source | Title |
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