Investigational Drug Details
| Drug ID: | D089 |
| Drug Name: | Cranberry |
| Synonyms: | -- |
| Type: | Biological drug |
| DrugBank ID: | DB10631 |
| DrugBank Description: | Cranberry allergenic extract is used in allergenic testing. |
| PubChem ID: | 13506 |
| CasNo: | 915-67-3 |
| Repositioning for NAFLD: | Yes |
| SMILES: | [Na].N(=N\c1c2c(c(cc1)S(=O)(=O)O)cccc2)/c1c2c(cc(c1O)S(=O)(=O)O)cc(cc2)S(=O)(=O)O |
| Structure: |
|
| InChiKey: | KSQCYWPBMKMMHA-QUABFQRHSA-N |
| Molecular Weight: | 562.535 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 3 on-going (IRCT20150124020765N2) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0774 | IRCT20150124020765N2 | Phase 3 | Recruiting | No Results Available | 06/01/2019 | 29 January 2019 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A01294 | 34798892 | BMC Complement Med Ther | Effect of cranberry supplementation on liver enzymes and cardiometabolic risk factors in patients with NAFLD: a randomized clinical trial. | Details |
| A08077 | 32256346 | Front Pharmacol | Hepatoprotective Effect of Cranberry Nutraceutical Extract in Non-alcoholic Fatty Liver Model in Rats: Impact on Insulin Resistance and Nrf-2 Expression. | Details |
| A08127 | 32237922 | Int J Food Sci Nutr | Combined cranberry supplementation and weight loss diet in non-alcoholic fatty liver disease: a double-blind placebo-controlled randomized clinical trial. | Details |
| A10375 | 31366865 | Biol Pharm Bull | Cranberry Attenuates Progression of Non-alcoholic Fatty Liver Disease Induced by High-Fat Diet in Mice. | Details |
| A12090 | 30606928 | Yakugaku Zasshi | [The Investigation of Genes, Using an Improved Adenovirus Vector, and Food for the Treatment and Prevention of Type 2 Diabetes Mellitus]. | Details |
| A17478 | 27619543 | J Nutr Biochem | Cranberry extract attenuates hepatic inflammation in high-fat-fed obese mice. | Details |
| A20553 | 25892149 | Food Funct | Ursolic acid inhibits the development of nonalcoholic fatty liver disease by attenuating endoplasmic reticulum stress. | Details |