Investigational Drug Details
| Drug ID: | D090 |
| Drug Name: | Crocin |
| Synonyms: | -- |
| Type: | Chemical drug |
| DrugBank ID: | DB11874 |
| DrugBank Description: | Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia. |
| PubChem ID: | 5281233 |
| CasNo: | 42553-65-1 |
| Repositioning for NAFLD: | No |
| SMILES: | C(O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O)[C@H]1O[C@@H](OC(=O)/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C(=O)O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O)[C@H]([C@@H]([C@H]2O)O)O)\C)\C)/C)/C)[C@@H]([C@H]([C@@H]1O)O)O |
| Structure: |
|
| InChiKey: | SEBIKDIMAPSUBY-RTJKDTQDSA-N |
| Molecular Weight: | 976.972 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 3 on-going (IRCT20180513039634N1) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0795 | IRCT20180513039634N1 | Phase 3 | Recruiting | No Results Available | 13/06/2018 | 16 July 2018 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A12054 | 30621686 | Lipids Health Dis | Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice. | Details |
| A17473 | 27770798 | BMC Complement Altern Med | Protective effects of saffron extract and crocin supplementation on fatty liver tissue of high-fat diet-induced obese rats. | Details |
| A49330 | 35786619 | Turk J Gastroenterol | Therapeutic Effect of Crocin on the NASH Model by Targeting the Fas Receptor Signaling Pathway. | Details |