Investigational Drugs

Investigational drugs for NAFLD are derived from global clinical trials with the latest progress, and detailed drug properties are extracted from DrugBank and PubChem. For each drug, related therapeutic strategies, targets, and clinical trials in NAFLDkb are presented with knowledge graphs.

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     platelet aggregation
11 records.
Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D002 Acetaminophen Chemical drug DB00316 PTGES3 inhibitor; TRPV1 activator Antipyretic drug; non-narcotic analgesic Under clinical trials Details
D018 Aspirin Chemical drug DB00945 AKR1C1 inhibitor; PCNA downregulator Enhance lipid metabolism Under clinical trials Details
D033 Bezafibrate Chemical drug DB01393 PPARA agonist; PPARD agonist; PPARG agonist; NR1I2 partial agonist Improve insulin resistance; Anti-inflammatory Under clinical trials Details
D092 Curcumin Chemical drug DB11672 PPARG; COX inhibitor Anticancer agent; NSAID Under clinical trials Details
D096 Dabigatran Etexilate Chemical drug DB06695 thrombin inhibitor -- Under clinical trials Details
D105 DHA Chemical drug DB03756 PPARA ligand; PPARG ligand Anti-inflammatory Under clinical trials Details
D266 Pentoxifylline Chemical drug DB00806 ADORA2A antagonist; ADORA1 antagonist; PDE4A inhibitor; PDE3B inhibitor; PDE4B inhibitor; PDE5A inhibitor; PDE8A inhibitor; PDE4C inhibitor; PDE11A inhibitor; PDE7A inhibitor; PDE7B inhibitor; PDE4D inhibitor; PDE3A inhibitor Anti-inflammatory; Cardiovascular drug Under clinical trials Details
D318 Salsalate Chemical drug DB01399 PTGS2 inhibitor; PTGS1 inhibitor NSAID Under clinical trials Details
D385 Vitamin B6 Supplement DB00165 PDXK ligand -- Under clinical trials Details
D474 Cilostazol Chemical drug DB01166 -- -- Under clinical trials Details
D568 ML355 Chemical drug -- 12-lipoxygenase inhibitor Platelet aggregation inhibitor Under investigation Details