Therapeutic Strategy Details
| Strategy ID: | S14 |
| Strategy: | Digital therapeutics |
| Other Terms: | Internet-based approach; Web-Based Exercise; Mobile Technology; Mobile APP |
| Related Targets: | None |
| Related Drugs: | None |
| Mechanism: | With the help of the Internet technology, digital therapeutics overcome these disadvantages and has achieved a certain clinical effect in NAFLD patients. A web-based intervention may be better suited for young, busy patients, and for those living far from liver units. Lifestyle intervention enabled by a mobile app can be effective in improving anthropometric indices and liver enzymes in patients with NAFLD. Clinical trial number: NCT02526732. |
| Reference (PMIDs): | 30290973; 30602434; 31342533; 32281943; 33939147 |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A02824 | 34229038 | Clin Gastroenterol Hepatol | A Global Survey of Physicians Knowledge About Nonalcoholic Fatty Liver Disease. | Details |
| A04921 | 33448929 | J Med Internet Res | Digital Intervention With Lifestyle Coach Support to Target Dietary and Physical Activity Behaviors of Adults With Nonalcoholic Fatty Liver Disease: Systematic Development Process of VITALISE Using Intervention Mapping. | Details |
| A08043 | 32271954 | Acta Paediatr | Survey on screening for paediatric non-alcoholic fatty liver disease in clinical practice in Dutch hospitals. | Details |
| A08714 | 32013841 | Curr Pharm Des | Lifestyle Changes for the Treatment of Nonalcoholic Fatty Liver Disease - A 2015-19 Update. | Details |
| A10382 | 31362471 | Korean J Intern Med | The quality of non-alcoholic fatty liver disease information resources for patients on the internet in Korea. | Details |
| A10423 | 31342533 | Aliment Pharmacol Ther | Improvement of non-invasive markers of NAFLD from an individualised, web-based exercise program. | Details |
| A10603 | 31274677 | J Am Assoc Nurse Pract | Readiness for the epidemic: The adult nonalcoholic fatty liver disease toolkit for primary care nurse practitioners. | Details |
| A12100 | 30602434 | J Med Internet Res | Web-Based Exercise as an Effective Complementary Treatment for Patients With Nonalcoholic Fatty Liver Disease: Intervention Study. | Details |
| A12782 | 30290973 | J Hepatol | An internet-based approach for lifestyle changes in patients with NAFLD: Two-year effects on weight loss and surrogate markers. | Details |
| A15880 | 28674352 | Intern Med | A Customized Online Nutrition Guidance System Is Effective for Treating Patients with Nonalcoholic Fatty Liver Disease by Supporting Continuity of Diet Therapy at Home: A Pilot Study. | Details |
| A18679 | 27001641 | Int J Obes (Lond) | Sweeteners and health: findings from recent research and their impact on obesity and related metabolic conditions. | Details |
| A18756 | 26969270 | BMC Res Notes | Awareness of nonalcoholic steatohepatitis and associated practice patterns of primary care physicians and specialists. | Details |
| A21177 | 25500563 | PLoS Comput Biol | SteatoNet: the first integrated human metabolic model with multi-layered regulation to investigate liver-associated pathologies. | Details |
| A21260 | 25450718 | J Hepatol | Bioinformatics and database resources in hepatology. | Details |
| A22041 | 24855432 | Paediatr Child Health | Parental perceptions regarding lifestyle interventions for obese children and adolescents with nonalcoholic fatty liver disease. | Details |
| A22042 | 24855423 | Paediatr Child Health | Parental perceptions regarding lifestyle interventions for obese children and adolescents with nonalcoholic fatty liver disease. | Details |
| A29468 | 34024977 | Ann Oper Res | Cooperation and decision making in a two-sided market motivated by the externality of a third-party social media platform. | Details |
| A29816 | 33465129 | PLoS One | Multi-energy conversion based on game theory in the industrial interconnection. | Details |
| A29859 | 33383753 | Sensors (Basel) | Joint Spreading Factor and Channel Assignment in Multi-Operator LoRaWAN Deployments. | Details |
| A29866 | 33371246 | Sensors (Basel) | Distributed Group Location Update Algorithm for Massive Machine Type Communication. | Details |