Clinical Trial Details

Trial ID: L0190
Source ID: NCT04822181
Associated Drug: Semaglutide
Title: Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
Acronym: ESSENCE
Status: Recruiting
Study Results: No Results Available
Results: --
Conditions: Non-alcoholic Steatohepatitis
Interventions: Drug: Semaglutide|Drug: Placebo
Outcome Measures: Part 1: Resolution of steatohepatitis and no worsening of liver fibrosis (Yes/No)|Part 1: Improvement in liver fibrosis and no worsening of steatohepatitis (Yes/No)|Part 2: Time to first liver-related clinical event (composite endpoint)|Progression of liver fibrosis (Yes/No)|Change in body weight|Change in SF-36 (Short Form 36) Bodily Pain|Improvement in steatohepatitis with at least a 2-point reduction in NAS and no worsening of fibrosis (Yes/No)|Change in histology-assessed liver collagen proportionate area|Resolution of steatohepatitis and improvement in liver fibrosis (Yes/No)|Worsening in steatohepatitis (Yes/No)|Improvement in histology-assessed ballooning (Yes/No)|Improvement in histology-assessed inflammation (Yes/No)|Improvement in histology-assessed steatosis (Yes/No)|Resolution of steatohepatitis and no worsening of liver fibrosis (Yes/No)|Improvement in liver fibrosis and no worsening of steatohepatitis (Yes/No)|Change in ALT (alanine aminotransferase)|Change in AST (aspartate aminotransferase)|Change in inflammation assessed by hsCRP (High Sensitive C-Reactive Protein)|Change in HbA1c (glycated haemoglobin)|Change in triglyceride|Change in free fatty acids|Change in LDL (low-density lipoprotein) cholesterol|Change in HDL (High density lipoprotein ) cholesterol|Changes in SF-36 (Short Form 36 v2.0 acute ) Physical Component Summary|Changes in SF-36 Mental Component Summary|Changes in NASH-CHECK Pain|Time to first MACE(Major Adverse Cardiovascular event ) (composite endpoint)|Time to first major cardio-hepatic event (composite endpoint)|Change in liver stiffness assessed by FibroScan??|Change in ELF (Enhanced Liver Fibrosis) score
Sponsor/Collaborators: Novo Nordisk A/S
Gender: All
Age: 18 Years and older ?? (Adult, Older Adult)
Phases: Phase 3
Enrollment: 1200
Study Type: Interventional
Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Masking: Double (Participant, Investigator)|Primary Purpose: Treatment
Start Date: April 1, 2021
Completion Date: May 26, 2028
Results First Posted: --
Last Update Posted: March 11, 2022
Locations: Novo Nordisk Investigational Site, Huntsville, Alabama, United States|Novo Nordisk Investigational Site, Chandler, Arizona, United States|Novo Nordisk Investigational Site, Peoria, Arizona, United States|Novo Nordisk Investigational Site, Tucson, Arizona, United States|Novo Nordisk Investigational Site, Tucson, Arizona, United States|Novo Nordisk Investigational Site, Little Rock, Arkansas, United States|Novo Nordisk Investigational Site, Hacienda Heights, California, United States|Novo Nordisk Investigational Site, La Jolla, California, United States|Novo Nordisk Investigational Site, Lancaster, California, United States|Novo Nordisk Investigational Site, Long Beach, California, United States|Novo Nordisk Investigational Site, Pasadena, California, United States|Novo Nordisk Investigational Site, Rialto, California, United States|Novo Nordisk Investigational Site, Sacramento, California, United States|Novo Nordisk Investigational Site, San Francisco, California, United States|Novo Nordisk Investigational Site, San Jose, California, United States|Novo Nordisk Investigational Site, Doral, Florida, United States|Novo Nordisk Investigational Site, Gainesville, Florida, United States|Novo Nordisk Investigational Site, Hialeah, Florida, United States|Novo Nordisk Investigational Site, Hialeah, Florida, United States|Novo Nordisk Investigational Site, Maitland, Florida, United States|Novo Nordisk Investigational Site, Miami Lakes, Florida, United States|Novo Nordisk Investigational Site, Miami, Florida, United States|Novo Nordisk Investigational Site, Miami, Florida, United States|Novo Nordisk Investigational Site, Miami, Florida, United States|Novo Nordisk Investigational Site, Ocala, Florida, United States|Novo Nordisk Investigational Site, Ocoee, Florida, United States|Novo Nordisk Investigational Site, Palmetto Bay, Florida, United States|Novo Nordisk Investigational Site, Sarasota, Florida, United States|Novo Nordisk Investigational Site, Zephyrhills, Florida, United States|Novo Nordisk Investigational Site, Columbus, Georgia, United States|Novo Nordisk Investigational Site, Macon, Georgia, United States|Novo Nordisk Investigational Site, Marietta, Georgia, United States|Novo Nordisk Investigational Site, Chicago, Illinois, United States|Novo Nordisk Investigational Site, Skokie, Illinois, United States|Novo Nordisk Investigational Site, Indianapolis, Indiana, United States|Novo Nordisk Investigational Site, South Bend, Indiana, United States|Novo Nordisk Investigational Site, Clive, Iowa, United States|Novo Nordisk Investigational Site, Topeka, Kansas, United States|Novo Nordisk Investigational Site, Marrero, Louisiana, United States|Novo Nordisk Investigational Site, Shreveport, Louisiana, United States|Novo Nordisk Investigational Site, Baltimore, Maryland, United States|Novo Nordisk Investigational Site, Glen Burnie, Maryland, United States|Novo Nordisk Investigational Site, Ann Arbor, Michigan, United States|Novo Nordisk Investigational Site, Detroit, Michigan, United States|Novo Nordisk Investigational Site, Jackson, Mississippi, United States|Novo Nordisk Investigational Site, Chesterfield, Missouri, United States|Novo Nordisk Investigational Site, Kansas City, Missouri, United States|Novo Nordisk Investigational Site, Omaha, Nebraska, United States|Novo Nordisk Investigational Site, Las Vegas, Nevada, United States|Novo Nordisk Investigational Site, Florham Park, New Jersey, United States|Novo Nordisk Investigational Site, New York, New York, United States|Novo Nordisk Investigational Site, New York, New York, United States|Novo Nordisk Investigational Site, Charlotte, North Carolina, United States|Novo Nordisk Investigational Site, Concord, North Carolina, United States|Novo Nordisk Investigational Site, Durham, North Carolina, United States|Novo Nordisk Investigational Site, Columbus, Ohio, United States|Novo Nordisk Investigational Site, Tulsa, Oklahoma, United States|Novo Nordisk Investigational Site, Hershey, Pennsylvania, United States|Novo Nordisk Investigational Site, Philadelphia, Pennsylvania, United States|Novo Nordisk Investigational Site, Philadelphia, Pennsylvania, United States|Novo Nordisk Investigational Site, Pittsburgh, Pennsylvania, United States|Novo Nordisk Investigational Site, Pottsville, Pennsylvania, United States|Novo Nordisk Investigational Site, Lincoln, Rhode Island, United States|Novo Nordisk Investigational Site, Charleston, South Carolina, United States|Novo Nordisk Investigational Site, Chattanooga, Tennessee, United States|Novo Nordisk Investigational Site, Hermitage, Tennessee, United States|Novo Nordisk Investigational Site, Johnson City, Tennessee, United States|Novo Nordisk Investigational Site, Nashville, Tennessee, United States|Novo Nordisk Investigational Site, Arlington, Texas, United States|Novo Nordisk Investigational Site, Dallas, Texas, United States|Novo Nordisk Investigational Site, Dallas, Texas, United States|Novo Nordisk Investigational Site, Dallas, Texas, United States|Novo Nordisk Investigational Site, Fort Worth, Texas, United States|Novo Nordisk Investigational Site, Houston, Texas, United States|Novo Nordisk Investigational Site, Houston, Texas, United States|Novo Nordisk Investigational Site, Houston, Texas, United States|Novo Nordisk Investigational Site, Houston, Texas, United States|Novo Nordisk Investigational Site, Houston, Texas, United States|Novo Nordisk Investigational Site, McAllen, Texas, United States|Novo Nordisk Investigational Site, Pearland, Texas, United States|Novo Nordisk Investigational Site, San Antonio, Texas, United States|Novo Nordisk Investigational Site, San Antonio, Texas, United States|Novo Nordisk Investigational Site, Sugar Land, Texas, United States|Novo Nordisk Investigational Site, Wichita Falls, Texas, United States|Novo Nordisk Investigational Site, Riverton, Utah, United States|Novo Nordisk Investigational Site, Salt Lake City, Utah, United States|Novo Nordisk Investigational Site, Charlottesville, Virginia, United States|Novo Nordisk Investigational Site, Falls Church, Virginia, United States|Novo Nordisk Investigational Site, Norfolk, Virginia, United States|Novo Nordisk Investigational Site, Richmond, Virginia, United States|Novo Nordisk Investigational Site, Richmond, Virginia, United States|Novo Nordisk Investigational Site, Richmond, Virginia, United States|Novo Nordisk Investigational Site, Roanoke, Virginia, United States|Novo Nordisk Investigational Site, Caba, Argentina|Novo Nordisk Investigational Site, Caba, Argentina|Novo Nordisk Investigational Site, Capital Federal, Argentina|Novo Nordisk Investigational Site, Ciudad de Buenos Aires, Argentina|Novo Nordisk Investigational Site, Florencio Varela, Buenos Aires, Argentina|Novo Nordisk Investigational Site, Rosario, Santa Fe, Argentina|Novo Nordisk Investigational Site, Camperdown, New South Wales, Australia|Novo Nordisk Investigational Site, Kingswood, New South Wales, Australia|Novo Nordisk Investigational Site, Westmead, New South Wales, Australia|Novo Nordisk Investigational Site, Elizabeth Vale, South Australia, Australia|Novo Nordisk Investigational Site, Fitzroy, Victoria, Australia|Novo Nordisk Investigational Site, Heidelberg, Victoria, Australia|Novo Nordisk Investigational Site, Nedlands, Western Australia, Australia|Novo Nordisk Investigational Site, Graz, Austria|Novo Nordisk Investigational Site, Salzburg, Austria|Novo Nordisk Investigational Site, Wels, Austria|Novo Nordisk Investigational Site, Wien, Austria|Novo Nordisk Investigational Site, Bruxelles, Belgium|Novo Nordisk Investigational Site, Bruxelles, Belgium|Novo Nordisk Investigational Site, Edegem, Belgium|Novo Nordisk Investigational Site, Genk, Belgium|Novo Nordisk Investigational Site, Gent, Belgium|Novo Nordisk Investigational Site, Salvador, Bahia, Brazil|Novo Nordisk Investigational Site, Goi??nia, Goias, Brazil|Novo Nordisk Investigational Site, Botucatu, Sao Paulo, Brazil|Novo Nordisk Investigational Site, S??o Jos?? do Rio Preto, Sao Paulo, Brazil|Novo Nordisk Investigational Site, S??o Paulo, Sao Paulo, Brazil|Novo Nordisk Investigational Site, S??o Paulo, Sao Paulo, Brazil|Novo Nordisk Investigational Site, Rio de Janeiro, Brazil|Novo Nordisk Investigational Site, Sofia, Bulgaria|Novo Nordisk Investigational Site, Sofia, Bulgaria|Novo Nordisk Investigational Site, Sofia, Bulgaria|Novo Nordisk Investigational Site, Sofia, Bulgaria|Novo Nordisk Investigational Site, Sofia, Bulgaria|Novo Nordisk Investigational Site, Varna, Bulgaria|Novo Nordisk Investigational Site, Calgary, Alberta, Canada|Novo Nordisk Investigational Site, Vancouver, British Columbia, Canada|Novo Nordisk Investigational Site, London, Ontario, Canada|Novo Nordisk Investigational Site, Toronto, Ontario, Canada|Novo Nordisk Investigational Site, Vaughan, Ontario, Canada|Novo Nordisk Investigational Site, Chicoutimi, Quebec, Canada|Novo Nordisk Investigational Site, Montreal, Quebec, Canada|Novo Nordisk Investigational Site, Montreal, Quebec, Canada|Novo Nordisk Investigational Site, Sherbrooke, Quebec, Canada|Novo Nordisk Investigational Site, Terrebonne, Quebec, Canada|Novo Nordisk Investigational Site, Beijing, Beijing, China|Novo Nordisk Investigational Site, Beijing, Beijing, China|Novo Nordisk Investigational Site, Beijing, Beijing, China|Novo Nordisk Investigational Site, Beijing, Beijing, China|Novo Nordisk Investigational Site, Chongqing, Chongqing, China|Novo Nordisk Investigational Site, Foshan, Guangdong, China|Novo Nordisk Investigational Site, Guangzhou, Guangdong, China|Novo Nordisk Investigational Site, Guangzhou, Guangdong, China|Novo Nordisk Investigational Site, Guangzhou, Guangdong, China|Novo Nordisk Investigational Site, Shijiazhuang, Hebei, China|Novo Nordisk Investigational Site, Nanjing, Jiangsu, China|Novo Nordisk Investigational Site, Zhenjiang, Jiangsu, China|Novo Nordisk Investigational Site, Changchun, Jilin, China|Novo Nordisk Investigational Site, Yinchuan, Ningxia, China|Novo Nordisk Investigational Site, Qingdao, Shandong, China|Novo Nordisk Investigational Site, Shanghai, Shanghai, China|Novo Nordisk Investigational Site, Shanghai, Shanghai, China|Novo Nordisk Investigational Site, Shanghai, Shanghai, China|Novo Nordisk Investigational Site, Tianjin, Tianjin, China|Novo Nordisk Investigational Site, Beijing, China|Novo Nordisk Investigational Site, Osijek, Croatia|Novo Nordisk Investigational Site, Rijeka, Croatia|Novo Nordisk Investigational Site, Zagreb, Croatia|Novo Nordisk Investigational Site, Liberec, Czechia|Novo Nordisk Investigational Site, Prague 2, Czechia|Novo Nordisk Investigational Site, Aarhus N, Denmark|Novo Nordisk Investigational Site, Hvidovre, Denmark|Novo Nordisk Investigational Site, Angers, France|Novo Nordisk Investigational Site, Clichy, France|Novo Nordisk Investigational Site, Lille, France|Novo Nordisk Investigational Site, NICE cedex 3, France|Novo Nordisk Investigational Site, Paris, France|Novo Nordisk Investigational Site, Paris, France|Novo Nordisk Investigational Site, Pessac, France|Novo Nordisk Investigational Site, Pierre Benite, France|Novo Nordisk Investigational Site, Strasbourg, France|Novo Nordisk Investigational Site, Berlin, Germany|Novo Nordisk Investigational Site, Berlin, Germany|Novo Nordisk Investigational Site, Bonn, Germany|Novo Nordisk Investigational Site, Frankfurt, Germany|Novo Nordisk Investigational Site, Hannover, Germany|Novo Nordisk Investigational Site, Leipzig, Germany|Novo Nordisk Investigational Site, L??beck, Germany|Novo Nordisk Investigational Site, Mainz, Germany|Novo Nordisk Investigational Site, W??rzburg, Germany|Novo Nordisk Investigational Site, Athens, Greece|Novo Nordisk Investigational Site, Athens, Greece|Novo Nordisk Investigational Site, Goudi, Athens, Greece|Novo Nordisk Investigational Site, Ioannina, Greece|Novo Nordisk Investigational Site, Larissa, Greece|Novo Nordisk Investigational Site, Thessaloniki, Greece|Novo Nordisk Investigational Site, Thessaloniki, Greece|Novo Nordisk Investigational Site, Thessaloniki, Greece|Novo Nordisk Investigational Site, Surat, Gujarat, India|Novo Nordisk Investigational Site, Mumbai, Maharashtra, India|Novo Nordisk Investigational Site, Nagpur, Maharashtra, India|Novo Nordisk Investigational Site, Delhi, New Delhi, India|Novo Nordisk Investigational Site, Chandigarh, Punjab, India|Novo Nordisk Investigational Site, Mohali, Punjab, India|Novo Nordisk Investigational Site, Jaipur, Rajasthan, India|Novo Nordisk Investigational Site, Jaipur, Rajasthan, India|Novo Nordisk Investigational Site, Lucknow, Uttar Pradesh, India|Novo Nordisk Investigational Site, Ludhiana, India|Novo Nordisk Investigational Site, New Delhi, India|Novo Nordisk Investigational Site, Dublin, Ireland|Novo Nordisk Investigational Site, Dublin, Ireland|Novo Nordisk Investigational Site, Haifa, Israel|Novo Nordisk Investigational Site, Jerusalem, Israel|Novo Nordisk Investigational Site, Jerusalem, Israel|Novo Nordisk Investigational Site, Petah-Tikva, Israel|Novo Nordisk Investigational Site, Ramat-Gan, Israel|Novo Nordisk Investigational Site, Tel Aviv, Israel|Novo Nordisk Investigational Site, Bologna, Italy|Novo Nordisk Investigational Site, Catanzaro, Italy|Novo Nordisk Investigational Site, Foggia, Italy|Novo Nordisk Investigational Site, Milano, Italy|Novo Nordisk Investigational Site, Palermo, Italy|Novo Nordisk Investigational Site, Rome, Italy|Novo Nordisk Investigational Site, Torino, Italy|Novo Nordisk Investigational Site, Bunkyo-ku, Tokyo, Japan|Novo Nordisk Investigational Site, Bunkyo-ku, Tokyo, Japan|Novo Nordisk Investigational Site, Fukui-shi, Fukui, Japan|Novo Nordisk Investigational Site, Hamamatsu-shi, Shizuoka, Japan|Novo Nordisk Investigational Site, Hatsukaichi-shi, Hiroshima, Japan|Novo Nordisk Investigational Site, Hiroshima-shi, Hiroshima, Japan|Novo Nordisk Investigational Site, Hiroshima-shi, Hiroshima, Japan|Novo Nordisk Investigational Site, Izunokuni-shi, Shizuoka, Japan|Novo Nordisk Investigational Site, Kagoshima-shi, Kagoshima, Japan|Novo Nordisk Investigational Site, Kamigyo-ku, Kyoto, Japan|Novo Nordisk Investigational Site, Kanazawa-shi, Ishikawa, Japan|Novo Nordisk Investigational Site, Kashihara-shi, Nara, Japan|Novo Nordisk Investigational Site, Kawasaki-shi, Kanagawa, Japan|Novo Nordisk Investigational Site, Kumamoto-shi, Kumamoto, Japan|Novo Nordisk Investigational Site, Minato-ku, Tokyo, Japan|Novo Nordisk Investigational Site, Musashino-shi, Tokyo, Japan|Novo Nordisk Investigational Site, Nagakute-shi, Aichi, Japan|Novo Nordisk Investigational Site, Nakagamigun, Okinawa, Japan|Novo Nordisk Investigational Site, Nara-shi, Nara, Japan|Novo Nordisk Investigational Site, Nishinomiya-shi, Hyogo, Japan|Novo Nordisk Investigational Site, Oita-shi, Oita, Japan|Novo Nordisk Investigational Site, Okayama-shi, Okayama, Japan|Novo Nordisk Investigational Site, Osaka-shi, Osaka, Japan|Novo Nordisk Investigational Site, Otsu-shi, Shiga, Japan|Novo Nordisk Investigational Site, Saga-shi, Saga, Japan|Novo Nordisk Investigational Site, Sapporo-shi, Hokkaido, Japan|Novo Nordisk Investigational Site, Sendai-shi, Miyagi, Japan|Novo Nordisk Investigational Site, Shinjuku-ku, Tokyo, Japan|Novo Nordisk Investigational Site, Suita-shi, Osaka, Japan|Novo Nordisk Investigational Site, Suita-shi, Osaka, Japan|Novo Nordisk Investigational Site, Takamatsu-shi, Kagawa, Japan|Novo Nordisk Investigational Site, Takasaki-shi, Gunma, Japan|Novo Nordisk Investigational Site, Tokyo, Japan|Novo Nordisk Investigational Site, Toon-shi, Ehime, Japan|Novo Nordisk Investigational Site, Wakayama-shi, Wakayama, Japan|Novo Nordisk Investigational Site, Yokohama-shi, Kanagawa, Japan|Novo Nordisk Investigational Site, Daegu, Korea, Republic of|Novo Nordisk Investigational Site, Daegu, Korea, Republic of|Novo Nordisk Investigational Site, Gangwon-do, Korea, Republic of|Novo Nordisk Investigational Site, Gyeonggi-do, Korea, Republic of|Novo Nordisk Investigational Site, Seoul, Korea, Republic of|Novo Nordisk Investigational Site, Seoul, Korea, Republic of|Novo Nordisk Investigational Site, Seoul, Korea, Republic of|Novo Nordisk Investigational Site, Seoul, Korea, Republic of|Novo Nordisk Investigational Site, Batu Caves, Malaysia|Novo Nordisk Investigational Site, Kota Bharu, Kelantan, Malaysia|Novo Nordisk Investigational Site, Kuala Lumpur, Malaysia|Novo Nordisk Investigational Site, Acapulco de Juarez, Guerrero, Mexico|Novo Nordisk Investigational Site, Guadalajara, Jalisco, Mexico|Novo Nordisk Investigational Site, Ciudad de M??xico, M??xico, D.F., Mexico|Novo Nordisk Investigational Site, Monterrey, Nuevo Le??n, Mexico|Novo Nordisk Investigational Site, Merida, Yucatan, Mexico|Novo Nordisk Investigational Site, Alkmaar, Netherlands|Novo Nordisk Investigational Site, Amsterdam, Netherlands|Novo Nordisk Investigational Site, Leiden, Netherlands|Novo Nordisk Investigational Site, Gjettum, Norway|Novo Nordisk Investigational Site, Oslo, Norway|Novo Nordisk Investigational Site, Bydgoszcz, Poland|Novo Nordisk Investigational Site, Mys??owice, Poland|Novo Nordisk Investigational Site, Wroclaw, Poland|Novo Nordisk Investigational Site, Almada, Portugal|Novo Nordisk Investigational Site, Aveiro, Portugal|Novo Nordisk Investigational Site, Braga, Portugal|Novo Nordisk Investigational Site, Guarda, Portugal|Novo Nordisk Investigational Site, Guimar??es, Portugal|Novo Nordisk Investigational Site, Lisboa, Portugal|Novo Nordisk Investigational Site, Matosinhos, Portugal|Novo Nordisk Investigational Site, Porto, Portugal|Novo Nordisk Investigational Site, Viana do Castelo, Portugal|Novo Nordisk Investigational Site, Vila Nova de Gaia, Portugal|Novo Nordisk Investigational Site, Vila Real, Portugal|Novo Nordisk Investigational Site, San Juan, Puerto Rico|Novo Nordisk Investigational Site, Bucharest, Romania|Novo Nordisk Investigational Site, Bucuresti, Romania|Novo Nordisk Investigational Site, Constanta, Romania|Novo Nordisk Investigational Site, Iasi, Romania|Novo Nordisk Investigational Site, Arkhangelsk, Russian Federation|Novo Nordisk Investigational Site, Barnaul, Russian Federation|Novo Nordisk Investigational Site, Kazan, Russian Federation|Novo Nordisk Investigational Site, Kazan, Russian Federation|Novo Nordisk Investigational Site, Moscow, Russian Federation|Novo Nordisk Investigational Site, Moscow, Russian Federation|Novo Nordisk Investigational Site, Novosibirsk, Russian Federation|Novo Nordisk Investigational Site, Penza, Russian Federation|Novo Nordisk Investigational Site, Saint Petersburg, Russian Federation|Novo Nordisk Investigational Site, Saint Petersburg, Russian Federation|Novo Nordisk Investigational Site, Saint-Petersburg, Russian Federation|Novo Nordisk Investigational Site, Saint-Petersburg, Russian Federation|Novo Nordisk Investigational Site, Saint-Petersburg, Russian Federation|Novo Nordisk Investigational Site, Tomsk, Russian Federation|Novo Nordisk Investigational Site, Ulianovsk, Russian Federation|Novo Nordisk Investigational Site, Yoshkar-Ola, Russian Federation|Novo Nordisk Investigational Site, Belgrade, Serbia|Novo Nordisk Investigational Site, Belgrade, Serbia|Novo Nordisk Investigational Site, Belgrade, Serbia|Novo Nordisk Investigational Site, Novi Sad, Serbia|Novo Nordisk Investigational Site, Bratislava, Slovakia|Novo Nordisk Investigational Site, Bratislava, Slovakia|Novo Nordisk Investigational Site, Trnava, Slovakia|Novo Nordisk Investigational Site, Port Elizabeth, Eastern Cape, South Africa|Novo Nordisk Investigational Site, Johannesburg, Gauteng, South Africa|Novo Nordisk Investigational Site, Lenasia, Gauteng, South Africa|Novo Nordisk Investigational Site, Cape Town, South Africa|Novo Nordisk Investigational Site, Majadahonda, Spain|Novo Nordisk Investigational Site, Pontevedra, Spain|Novo Nordisk Investigational Site, Santander, Spain|Novo Nordisk Investigational Site, Sevilla, Spain|Novo Nordisk Investigational Site, Valencia, Spain|Novo Nordisk Investigational Site, Valladolid, Spain|Novo Nordisk Investigational Site, Bern, Switzerland|Novo Nordisk Investigational Site, Geneva, Switzerland|Novo Nordisk Investigational Site, Olten, Switzerland|Novo Nordisk Investigational Site, St. Gallen, Switzerland|Novo Nordisk Investigational Site, Z??rich, Switzerland|Novo Nordisk Investigational Site, Chiayi City, Taiwan|Novo Nordisk Investigational Site, Kaoshiung, Taiwan|Novo Nordisk Investigational Site, Tainan City, Taiwan|Novo Nordisk Investigational Site, Taipei city, Taiwan|Novo Nordisk Investigational Site, Taipei city, Taiwan|Novo Nordisk Investigational Site, Taipei, Taiwan|Novo Nordisk Investigational Site, Taipei, Taiwan|Novo Nordisk Investigational Site, Ankara, Turkey|Novo Nordisk Investigational Site, Ankara, Turkey|Novo Nordisk Investigational Site, Ankara, Turkey|Novo Nordisk Investigational Site, Bursa, Turkey|Novo Nordisk Investigational Site, Istanbul, Turkey|Novo Nordisk Investigational Site, Istanbul, Turkey|Novo Nordisk Investigational Site, Istanbul, Turkey|Novo Nordisk Investigational Site, Istanbul, Turkey|Novo Nordisk Investigational Site, Istanbul, Turkey|Novo Nordisk Investigational Site, Izmir, Turkey|Novo Nordisk Investigational Site, Kocaeli, Turkey|Novo Nordisk Investigational Site, Mersin, Turkey|Novo Nordisk Investigational Site, Belfast, United Kingdom|Novo Nordisk Investigational Site, Birmingham, United Kingdom|Novo Nordisk Investigational Site, Coventry, United Kingdom|Novo Nordisk Investigational Site, Derby, United Kingdom|Novo Nordisk Investigational Site, Dundee, United Kingdom|Novo Nordisk Investigational Site, Exeter, United Kingdom|Novo Nordisk Investigational Site, Hull, United Kingdom|Novo Nordisk Investigational Site, Ipswich, United Kingdom|Novo Nordisk Investigational Site, Leeds, United Kingdom|Novo Nordisk Investigational Site, London, United Kingdom|Novo Nordisk Investigational Site, London, United Kingdom|Novo Nordisk Investigational Site, London, United Kingdom|Novo Nordisk Investigational Site, London, United Kingdom|Novo Nordisk Investigational Site, Newcastle-Upon Tyne, United Kingdom|Novo Nordisk Investigational Site, Nottingham, United Kingdom|Novo Nordisk Investigational Site, Oxford, United Kingdom|Novo Nordisk Investigational Site, Plymouth, United Kingdom|Novo Nordisk Investigational Site, Sheffield, United Kingdom|Novo Nordisk Investigational Site, Southampton, United Kingdom|Novo Nordisk Investigational Site, Swansea, United Kingdom
URL: https://ClinicalTrials.gov/show/NCT04822181

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D327 Semaglutide Chemical drug DB13928 GLP1R agonist Antidiabetic drug Under clinical trials Details
D199 L-alanine Chemical drug DB00160 KYNU -- Failed in clinical trials Details