| Trial ID: | L0217 |
| Source ID: | NCT00586885
|
| Associated Drug: |
L-alanine
|
| Title: |
Effects of Alanine in Patients With Nonalcoholic Steatohepatitis
|
| Acronym: |
--
|
| Status: |
Completed
|
| Study Results: |
No Results Available
|
| Results: |
--
|
| Conditions: |
Nonalcoholic Steatohepatitis
|
| Interventions: |
Drug: L-alanine
|
| Outcome Measures: |
To assess the safety and tolerability of long-term L-alanine supplementation and the therapeutic efficacy of long-term L-alanine supplementation by evaluating liver biochemistry and histological findings.|Determine the effect of L-alanine on gene profiles, anti-oxidant response and inflammatory response in hepatocytes. Evaluate possible correlation between therapeutic efficacy and gene profiles altered by L-alanine supplementation
|
| Sponsor/Collaborators: |
Keith D Lindor, M.D.|Ajinomoto USA, INC.|Mayo Clinic
|
| Gender: |
All
|
| Age: |
18 Years to 75 Years ?? (Adult, Older Adult)
|
| Phases: |
Not applicable
|
| Enrollment: |
9
|
| Study Type: |
Interventional
|
| Study Designs: |
Allocation: N/A|Intervention Model: Single Group Assignment|Masking: None (Open Label)|Primary Purpose: Treatment
|
| Start Date: |
February 2004
|
| Completion Date: |
June 2006
|
| Results First Posted: |
--
|
| Last Update Posted: |
October 11, 2012
|
| Locations: |
Mayo Clinic, Rochester, Minnesota, United States
|
| URL: |
https://ClinicalTrials.gov/show/NCT00586885
|
