Clinical Trial Details
| Trial ID: | L0247 |
| Source ID: | NCT01278056 |
| Associated Drug: | Deferasirox |
| Title: | The Impact of Deferasirox on Non-Alcoholic-Steatohepatitis |
| Acronym: | DEFINE |
| Status: | Completed |
| Study Results: | No Results Available |
| Results: | -- |
| Conditions: | Non-alcoholic Steatohepatitis|Increased Iron Storage / Disturbed Distribution |
| Interventions: | Drug: Exjade |
| Outcome Measures: | Safety and tolerability of deferasirox in all patients (Phase I)|Changes in liver histology in all patients (Phase II)|Phase I: e.g. changes in liver enzymes, serum ferritin, and hemoglobin levels|Phase II: e.g. changes in MRI and histology based assessment of hepatic steatosis, fibrosis and iron content |
| Sponsor/Collaborators: | Crolll Gmbh|Estimate, GmbH|University of Magdeburg |
| Gender: | All |
| Age: | 18 Years and older ?? (Adult, Older Adult) |
| Phases: | Phase 1/Phase 2 |
| Enrollment: | 5 |
| Study Type: | Interventional |
| Study Designs: | Allocation: N/A|Intervention Model: Single Group Assignment|Masking: None (Open Label)|Primary Purpose: Treatment |
| Start Date: | March 2010 |
| Completion Date: | July 2012 |
| Results First Posted: | -- |
| Last Update Posted: | July 20, 2012 |
| Locations: | Zollernalbklinikum, Balingen/Hechingen, Germany|Charit??, Virchow Klinikum, Berlin, Germany|Klinikum der J. W. Goethe-Universit??t, Med. Klinik I, Frankfurt, Germany|Universit??tsklinikum Halle, Klinik & Poliklinik f??r Innere Medizin I, Halle, Germany|Universit??tsklinikum des Saarlandes, Homburg/Saar, Germany|Universit??tsklinikum Magdeburg, Klinik f??r Gastroenterologie, Hepatologie und Infektiologie, Magdeburg, Germany|Universit??tsklinikum Mainz, I. Medizinische Klinik und Poliklinik, Mainz, Germany|Universit??tsklinikum Regensburg, Klinik und Poliklinik f??r Innere Med. I, Regensburg, Germany|Universit??tsklinikum T??bingen, Medizinische Klinik IV, T??bingen, Germany |
| URL: | https://ClinicalTrials.gov/show/NCT01278056 |
