Clinical Trial Details

Trial ID: L0253
Source ID: NCT00740610
Associated Drug: GS-9450
Title: Safety, Tolerability, Pharmacokinetics and Activity of GS-9450 in Adults With Non-Alcoholic Steatohepatitis (NASH)
Acronym: --
Status: Completed
Study Results: No Results Available
Results: --
Conditions: Nonalcoholic Steatohepatitis
Interventions: Drug: GS-9450|Drug: GS-9450 Placebo
Outcome Measures: Percentage of Participants Who Experienced Adverse Events (AEs) and Graded Laboratory Abnormalities|Pharmacokinetics of GS-9450 and its metabolites|Change from baseline in alanine aminotransferase (ALT)
Sponsor/Collaborators: Gilead Sciences
Gender: All
Age: 18 Years to 75 Years ?? (Adult, Older Adult)
Phases: Phase 2
Enrollment: 124
Study Type: Interventional
Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|Primary Purpose: Treatment
Start Date: August 2008
Completion Date: September 2009
Results First Posted: --
Last Update Posted: February 4, 2014
Locations: Tucson, Arizona, United States|Fresno, California, United States|Fullerton, California, United States|San Diego, California, United States|San Mateo, California, United States|Lakewood, Colorado, United States|Washington, District of Columbia, United States|Jacksonville, Florida, United States|Atlanta, Georgia, United States|Marietta, Georgia, United States|Chicago, Illinois, United States|Des Moines, Iowa, United States|Kansas City, Kansas, United States|Monroe, Louisiana, United States|New Orleans, Louisiana, United States|Ann Arbor, Michigan, United States|Troy, Michigan, United States|New York, New York, United States|Plainview, New York, United States|Syracuse, New York, United States|Asheville, North Carolina, United States|Durham, North Carolina, United States|Raleigh, North Carolina, United States|Clevleand, Ohio, United States|Providence, Rhode Island, United States|Dallas, Texas, United States|Galveston, Texas, United States|Irving, Texas, United States|Charlottesville, Virginia, United States|Falls Church, Virginia, United States|Richmond, Virginia, United States|Paris, France|Vandoeuvre les Nancy, France
URL: https://ClinicalTrials.gov/show/NCT00740610

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D244 Nivocasan Chemical drug DB12720 -- Protective drug Under clinical trials Details
D199 L-alanine Chemical drug DB00160 KYNU -- Failed in clinical trials Details