Clinical Trial Details

Trial ID: L0319
Source ID: NCT03028740
Associated Drug: Cenicriviroc
Title: AURORA: A Study for the Efficacy and Safety of Cenicriviroc (CVC) for the Treatment of Liver Fibrosis in Adults With Nonalcoholic Steatohepatitis (NASH)
Acronym: AURORA
Status: Terminated
Study Results: Has Results
Results: https://ClinicalTrials.gov/show/NCT03028740/results
Conditions: Nonalcoholic Steatohepatitis
Interventions: Drug: Placebo|Drug: Cenicriviroc
Outcome Measures: Part 1: Percentage of Participants With Improvement in Fibrosis by at Least 1 Stage and No Worsening of Steatohepatitis on Liver Histology at Month 12|Time to First Occurrence of Adjudicated Events in the Full Study Cohort|Part 1: Percentage of Participants With Improvement in Fibrosis by at Least 2 Stages and No Worsening of Steatohepatitis on Liver Histology at Month 12|Part 1: Percentage of Participants With Improvement in Fibrosis by at Least 1 Stage Regardless of Effect on Steatohepatitis at Month 12|Part 1: Percentage of Participants With Improvement in Fibrosis by at Least 2 Stages Regardless of Effect on Steatohepatitis at Month 12|Percentage of Participants With Improvement in Fibrosis by at Least 1 Stage and No Worsening of Steatohepatitis on Liver Biopsy at Month 12 in the Full Study Cohort|Percentage of Participants With Improvement in Fibrosis by at Least 1 Stage Regardless of Effect on Steatohepatitis on Liver Biopsy at Month 12 in the Full Study Cohort|Percentage of Participants With Improvement in Fibrosis by at Least 2 Stages and No Worsening of Steatohepatitis on Liver Biopsy at Month 12 in the Full Study Cohort|Percentage of Participants With Improvement in Fibrosis by at Least 2 Stages Regardless of Effect on Steatohepatitis on Liver Biopsy at Month 12 in the Full Study Cohort|Percentage of Participants With Improvement in Fibrosis by at Least 1 Stage and No Worsening of Steatohepatitis on Liver Biopsy at Month 60 in the Full Study Cohort|Percentage of Participants With Improvement in Fibrosis by at Least 1 Stage Regardless of Effect on Steatohepatitis on Liver Biopsy at Month 60 in the Full Study Cohort|Percentage of Participants With Improvement in Fibrosis by at Least 2 Stages and No Worsening of Steatohepatitis on Liver Biopsy at Month 60 in the Full Study Cohort|Percentage of Participants With Improvement in Fibrosis by at Least 2 Stages Regardless of Effect on Steatohepatitis on Liver Biopsy at Month 60 in the Full Study Cohort
Sponsor/Collaborators: Tobira Therapeutics, Inc.
Gender: All
Age: 18 Years to 75 Years ?? (Adult, Older Adult)
Phases: Phase 3
Enrollment: 1778
Study Type: Interventional
Study Designs: Allocation: Randomized|Intervention Model: Parallel Assignment|Masking: Double (Participant, Investigator)|Primary Purpose: Treatment
Start Date: April 5, 2017
Completion Date: March 9, 2021
Results First Posted: March 10, 2022
Last Update Posted: March 10, 2022
Locations: Summit Internal Medicine, Birmingham, Alabama, United States|Cullman Clinical Trials, Cullman, Alabama, United States|Digestive Health Specialists of the Southeast, Dothan, Alabama, United States|Objective GI D/B/A North Alabama GI Research Center, Madison, Alabama, United States|The Institute for Liver Health, Chandler, Arizona, United States|Adobe Gastroenterology Research, LLC, Tucson, Arizona, United States|Del Sol Research Management, LLC, Tucson, Arizona, United States|Del Sol Research Management LLC, Tucson, Arizona, United States|Arkansas Diagnostic Center, Little Rock, Arkansas, United States|Franco Felizarta MD, Bakersfield, California, United States|Hope Clinical Research, Canoga Park, California, United States|GW Research, Chula Vista, California, United States|eStudySite, Chula Vista, California, United States|Southern California Research Center, Coronado, California, United States|Citrus Valley Gastroenterology, Covina, California, United States|TriWest Research Associates, El Cajon, California, United States|University of San Francisco, Fresno Medical Education Program, Fresno, California, United States|Fresno Clinical Research Center (FCRC), Fresno, California, United States|National Research Institute, Huntington Park, California, United States|University of California San Diego, La Jolla, California, United States|eStudySite, La Mesa, California, United States|Om Research, Lancaster, California, United States|Southern California Kaiser Permanente, Los Angeles Medical Center, Los Angeles, California, United States|GastroIntestinal Biosciences, Los Angeles, California, United States|Global Research Institute, Los Angeles, California, United States|Ruane Medical and Liver Health Institute, Los Angeles, California, United States|Cedars-Sinai Medical Group, Los Angeles, California, United States|National Research Institute, Los Angeles, California, United States|United Medical Doctors, Murrieta, California, United States|Palmtree Clinical Research Inc., Palm Springs, California, United States|National Research Institute, Panorama City, California, United States|Pasadena Liver Center, Pasadena, California, United States|Alliance Clinical Research LLC, Poway, California, United States|Stanford School of Medicine, Center for Clinical Sciences Research, Redwood City, California, United States|Inland Empire Liver Foundation, Rialto, California, United States|Precision Research Institute, San Diego, California, United States|Southern California Permanente Medical Group, San Diego, California, United States|UCSF School of Medicine, San Francisco, California, United States|Upland Clinical Research, Upland, California, United States|Island View GI, Ventura, California, United States|Peak Gastroenterology Associates, Colorado Springs, Colorado, United States|South Denver Gastroenterology, PC, Englewood, Colorado, United States|Western States Clinical Research, Inc., Wheat Ridge, Colorado, United States|Gastroenterology Associates of Fairfield County, Bridgeport, Connecticut, United States|Yale University - New Haven, New Haven, Connecticut, United States|Innovative Medical Research of South Florida, Inc., Aventura, Florida, United States|Gastro Florida, Clearwater, Florida, United States|Hi Tech and Global Research, LLC, Coral Gables, Florida, United States|Top Medical Research, Inc, Cutler Bay, Florida, United States|ICR Sites, Doral, Florida, United States|Qway Research, LLC, Hialeah, Florida, United States|Gastroenterology Associates - Crystal River, Inverness, Florida, United States|Mayo Clinic College of Medicine, Jacksonville, Florida, United States|Meridien Research, Lakeland, Florida, United States|Florida Digestive Health Specialists, Lakewood Ranch, Florida, United States|Meridien Research, Maitland, Florida, United States|San Marcus Research Clinic, Miami Lakes, Florida, United States|Clinical Pharmacology of Miami, LLC, Miami, Florida, United States|Bruce W. Carter Department of Veterans Affairs Medical Center, Miami, Florida, United States|Optimus U Corporation, Miami, Florida, United States|University of Miami Hospital, Miami, Florida, United States|Sanchez Clinical Research, Inc, Miami, Florida, United States|Genoma Research Group Inc., Miami, Florida, United States|Medical Professional Clinical Research Center, INC, Miami, Florida, United States|ProLive Medical Research, Miami, Florida, United States|Advanced Research Institute, Inc., New Port Richey, Florida, United States|Bioclinical Research Alliance, Orlando, Florida, United States|Omega Research Maitland, LLC, Orlando, Florida, United States|IMIC, Inc, Palmetto Bay, Florida, United States|Innovation Medical Research Center, Palmetto Bay, Florida, United States|Gastroenterology Associates of Pensacola, Pensacola, Florida, United States|Advanced Medical Research, Port Orange, Florida, United States|Tampa General Hospital, Tampa, Florida, United States|Guardian Angel Research Center, Tampa, Florida, United States|Bioclinica Research, The Villages, Florida, United States|Florida Medical Clinic, Zephyrhills, Florida, United States|Summit Clinical Research, LLC, Athens, Georgia, United States|Digestive Healthcare of Georgia - Atlanta, Atlanta, Georgia, United States|Piedmont Healthcare INC., Atlanta, Georgia, United States|Gastroenterology Associates of Central Georgia, Macon, Georgia, United States|GI Specialists of Georgia - Marietta Office, Marietta, Georgia, United States|Northwestern University, Chicago, Illinois, United States|Rush University Medical Center, Chicago, Illinois, United States|Investigators Research Group, LLC, Brownsburg, Indiana, United States|Indianapolis Gastroenterology Research Foundation, Indianapolis, Indiana, United States|Aquiant Research, New Albany, Indiana, United States|Digestive Research Alliance of Michiana, South Bend, Indiana, United States|Iowa Digestive Disease Center, Clive, Iowa, United States|University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States|University of Kansas Medical Center, Kansas City, Kansas, United States|Kansas Medical Clinic-Gastroenterology, Topeka, Kansas, United States|Delta Research Partners, LLC, Bastrop, Louisiana, United States|Avant Research Associates LLC, Crowley, Louisiana, United States|C-1 Headlands, Inc., Lake Charles, Louisiana, United States|Tandem Clinical Research, Marrero, Louisiana, United States|Tulane University School of Medicine, New Orleans, Louisiana, United States|Ochsner Medical Center, New Orleans, Louisiana, United States|Nola Research Works, LLC, New Orleans, Louisiana, United States|Louisiana Research Center, Shreveport, Louisiana, United States|Clinical Trials of America LLC, West Monroe, Louisiana, United States|Mercy Medical Center, Baltimore, Maryland, United States|Digestive Disease Associates, Catonsville, Maryland, United States|Gastro Center of Maryland, Columbia, Maryland, United States|Woodholme Gastroenterology Associates, Glen Burnie, Maryland, United States|Victory Clinical Research, Greenbelt, Maryland, United States|Meritus Center for Clinical Research, Hagerstown, Maryland, United States|Massachusetts General Hospital, Boston, Massachusetts, United States|Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States|Lahey Hospital & Medical Center, Burlington, Massachusetts, United States|Umass Memorial Medical Center, Worcester, Massachusetts, United States|Henry Ford Health System, Detroit, Michigan, United States|Minnesota Gastroenterology, P.A., Maplewood, Minnesota, United States|National Diabetes and Obesity Research Institute, Biloxi, Mississippi, United States|GastroIntestinal Associates, Flowood, Mississippi, United States|Clinical Research Professionals, Chesterfield, Missouri, United States|Saint Louis University, Saint Louis, Missouri, United States|Washington University School of Medicine, Saint Louis, Missouri, United States|Machuca Family Medicine, Las Vegas, Nevada, United States|Jubilee Clinical Research, Inc., Las Vegas, Nevada, United States|Sierra Clinical Research, Las Vegas, Nevada, United States|Excel Clinical Research, Las Vegas, Nevada, United States|Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States|Hassman Research Institute, Berlin, New Jersey, United States|Amici Clinical Research, Raritan, New Jersey, United States|Beth Israel Medical Center, New York, New York, United States|NYU Langone Health - Perlmutter Cancer Center, New York, New York, United States|Mount Sinai Medical Center, New York, New York, United States|Tandem Clinical Research, New York, New York, United States|Weill Cornell Medical College, New York, New York, United States|Investigational Drug Service, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States|Carolinas Medical Center, Charlotte, North Carolina, United States|Northeast GI Research Division, Concord, North Carolina, United States|Duke University, Durham, North Carolina, United States|Cumberland Research Associates, LLC, Fayetteville, North Carolina, United States|Carolina Research, Greenville, North Carolina, United States|Wake Research Associates, Raleigh, North Carolina, United States|PMG Research of Winston-Salem, Winston-Salem, North Carolina, United States|Consultants for Clinical Research, Cincinnati, Ohio, United States|MetroHealth Medical Center, Cleveland, Ohio, United States|The Ohio University - Gastroenterology, Hepatology, Columbus, Ohio, United States|Digestive Disease Specialist, Inc., Oklahoma City, Oklahoma, United States|Options Health Research, Tulsa, Oklahoma, United States|Eastern Pennsylvania Gastroenterology and Liver Specialist, Bethlehem, Pennsylvania, United States|UPMC -Center for Liver Diseases, Pittsburgh, Pennsylvania, United States|VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, United States|Care Access Research, Pottsville, Pottsville, Pennsylvania, United States|Digestive Disease Associates, LTD, Wyomissing, Pennsylvania, United States|Partners in Clinical Research, Cumberland, Rhode Island, United States|University Medical Group, North Providence, Rhode Island, United States|Care Access Research-Warwick, Warwick, Rhode Island, United States|Rapid City Medical Center, Rapid City, South Dakota, United States|Mount Vernon Clinical Research, Chattanooga, Tennessee, United States|Gastro One, Germantown, Tennessee, United States|Digestive Health Research, Hermitage, Tennessee, United States|East Tennessee Research Institute, Johnson City, Tennessee, United States|Digestive Health Research, Lebanon, Tennessee, United States|UT-Memphis, Methodist University Hospital, Memphis, Tennessee, United States|Vanderbilt University, Nashville, Tennessee, United States|Texas Clinical Research Institute, Arlington, Texas, United States|Methodist Dallas Medical Center, Dallas, Texas, United States|Liver Center of Texas, Dallas, Texas, United States|Synexus, Dallas, Texas, United States|University of Texas Southwestern Medical Center, Dallas, Texas, United States|San Antonio Military Medical Center, Fort Sam Houston, Texas, United States|Baylor Scott & White All Saints Medical Center - Ft. Worth, Fort Worth, Texas, United States|Texas Digestive Disease Consultants - Fort Worth, Fort Worth, Texas, United States|Digestive Health Associates of Texas-Rockwall, Garland, Texas, United States|Therapeutic Concepts, PA, Houston, Texas, United States|Pioneer Research Solutions, Inc., Houston, Texas, United States|Liver Associates of Texas, Houston, Texas, United States|Baylor College of Medicine, Houston, Texas, United States|Michael E. DeBakey VA Medical Center (MEDVAMC), Houston, Texas, United States|St. Luke's Medical Center, Houston, Texas, United States|Biopharma Informatic, LLC, Houston, Texas, United States|Centex Studies, Houston, Texas, United States|Biopharma Informatic, LLC, Houston, Texas, United States|Amir Ali Hassan, MD, PA, Houston, Texas, United States|Centex Studies, Inc., McAllen, Texas, United States|LinQ Research, LLC, Pearland, Texas, United States|Quality Research Inc., San Antonio, Texas, United States|American Research Corporation, San Antonio, Texas, United States|Clinical Trials of Texas Inc, San Antonio, Texas, United States|Diabetes & Glandular Disease Clinic, P.A. (DGD), San Antonio, Texas, United States|Endeavor Clinical Trials, LLC, San Antonio, Texas, United States|Southern Star Research Institute, LLC SAGACT PLLC., San Antonio, Texas, United States|Anson Medicine, San Antonio, Texas, United States|Mount Olympus Medical Research, LLC, Sugar Land, Texas, United States|Texas Digestive Disease Consultants, Webster, Texas, United States|Physician's Research Options, LLC, Draper, Utah, United States|Intermountain Medical Center, Murray, Utah, United States|Advanced Clinical Research - Center for Digestive Health, Riverton, Utah, United States|University of Utah, Salt Lake City, Utah, United States|Gastroenterology Associates of Northern Virginia, Fairfax, Virginia, United States|Inova Fairfax Medical Campus, Falls Church, Virginia, United States|Liver Institute of Virginia, Newport News, Virginia, United States|Digestive and Liver Disease Specialists, Norfolk, Virginia, United States|McGuire Veterans Affairs Medical Center, Richmond, Virginia, United States|VCU Medical Center, Richmond, Virginia, United States|Gastroenterology Consultants of Southwest Virginia Research, Roanoke, Virginia, United States|Harborview Medical Center, Seattle, Washington, United States|Swedish Medical Center, Seattle, Washington, United States|Liver Institute Northwest, Seattle, Washington, United States|University of Washington Medical Center, Seattle, Washington, United States|Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia, United States|Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia|Saint George Hospital, Kogarah, New South Wales, Australia|Royal Brisbane and Women's Hospital, Herston, Queensland, Australia|Royal Adelaide Hospital, Adelaide, South Australia, Australia|Flinders Medical Center, Adelaide, South Australia, Australia|Monash Medical Centre, Clayton, Victoria, Australia|Austin Health, Heidelberg, Victoria, Australia|Royal Perth Hospital, Perth, Western Australia, Australia|Universitatsklinik far Innere Medizin, Graz, Styria, Austria|Universitatsklinik far Innere Medizin II, Innsbruck, Tyrol, Austria|Klinikum Wels-Grieskirchen, Wels, Upper Austria, Austria|Universitair Ziekenhuis Antwerpen, Edegem, Antwerpen, Belgium|H??pital Erasme, Bruxelles, Brussels, Belgium|Algemeen Ziekenhuis Maria Middelares, Gent, Oost-Vlaanderen, Belgium|Universitair Ziekenhuis Gent, Gent, Oost-Vlaanderen, Belgium|Cliniques Universitaires Saint-Luc, Brussels, Belgium|Centre Hospitalier Chretien CHC, Liege, Belgium|Hospital das Cl??nicas da Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil|Faculdade de Medicina de S??o Jos?? do Rio Preto Hospital de Base, S??o Jos?? do Rio Preto, Sao Paulo, Brazil|Hospital Universit??rio Clementino Fraga Filho, Rio de Janeiro, Brazil|Hospital das Cl??nicas da Faculdade de Medicina da Universidade de S??o Paulo, Sao Paulo, Brazil|University of Calgary Liver Unit, Calgary, Alberta, Canada|Bailey Health Clinic, Edmonton, Alberta, Canada|Vancouver General Hospital, Vancouver, British Columbia, Canada|William Osler Health Centre, Brampton Memorial Hospital Campus, Brampton, Ontario, Canada|Toronto Liver Centre, Toronto, Ontario, Canada|Ecogene-21, Chicoutimi, Quebec, Canada|Centro de Investigaciones Cl??nicas Vi??a del Mar, Vi??a del Mar, Valparaiso, Chile|CHU de Strasbourg, Strasbourg cedex, Alsace, France|CHU De Bordeaux - H??pital Ha??t-L??v??que CMC Magellan Unita de Recherche Clinique, Pessac, Aquitaine, France|Centre Hospitalier Universitaire Estaing, Clermont-Ferrand, Aubergne, France|Centre Hospitalier Universitaire de Rennes- H??pital Pontchaillou, Rennes, Bretagne, France|Centre Hospitalier Regional et Universitaire de Besancon - L'Hopital Jean Minjoz, Besan??on cedex, Franche-Comte, France|Departement d'Hacpatologie, Clichy, Ile-De-France, France|H??pital Saint Antoine, Paris Cedex 12, Ile-de-France, France|CHU de Montpellier, Montpellier cedex 5, Languedoc-Roussillon, France|Centre Hospitalier Universitaire de Rouen CHU de Rouen Hopital Charles-Nicolle, Rouen, Normandie, France|Center Hospitalier Universitaire d'Angers, Angers, Pays De La Loire, France|Hapital Sud Service d'Hepato- Gastroentarologie, Amiens Cedex 1, Picardie, France|Centre Hospitalier Universitaire de Nice H??pital l'Archet, Nice Cedex 3, Provence Alpes Cote D'Azur, France|Centre Hospitalier Universitaire Grenoble, Grenoble Cedex 09, Rhone-Alpes, France|Hopital Avicenne, Bobigny, France|Synexus Clinical Research GmbH, Pr??fzentrum Frankfurt, Frankfurt, Hessen, Germany|Philipps-Universit??t und Universit??tsklinikum Gie??en und Marburg GmbH, Marburg, Hessen, Germany|Medizinische Hochschule Hannover, Hannover, Niedersachsen, Germany|Gastroenterologische Gemeinschaftspraxis, Herne, Nordhein-Westfalen, Germany|Uniklinik RWTH Aachen, Aachen, Nordrhein-Westfalen, Germany|Uniklinik K??ln, K??ln, Nordrhein-westfalen, Germany|Universit??tsmedizin der Johannes Gutenberg Universit??t Mainz, Mainz, Rheinland-Pfalz, Germany|Universit??tsklinikum des Saarlandes, Homburg, Saarland, Germany|Universit??tsklinikum Leipzig, Leipzig, Sachsen, Germany|Praxis Driesener Strasse, Berlin, Germany|Synexus Clinical Research GmbH, Pr??fzentrum Berlin, Berlin, Germany|Charit?? Universit??tsmedizin Berlin, Berlin, Germany|Universit??tsklinikum Hamburg Eppendorf, Hamburg, Germany|Thomopoulos Gastroenterology Dept., Patra, Peloponnese, Greece|Hippokratio Hospital, Thessaloniki, Greece|Prince of Wales Hospital, Shatin, New Territories, Hong Kong|Alice Ho Miu Ling Nethersole Hospital, Shatin, New Territories, Hong Kong|Somogy Megyei Kaposi M??r Oktat?? K??rh??z, Kaposv??r, Somogy, Hungary|SYNEXUS Magyarorsz??g Kft. - Budapest DRS, Budapest, Hungary|Synexus Magyarorszag Egeszsegugyi Szolgaltato Kft, Debrecen, Hungary|EMMS MC, Nazareth, Jerusalem, Israel|Rambam Health Care Campus - Rambam Medical Center, Haifa, Israel|Carmel Medical Center, Haifa, Israel|Shaare Zedek Medical Center, Jerusalem, Israel|Hadassah Medical Center, Institute of Gastroenterology and Liver Diseases, Jerusalem, Israel|Galilee Medical Center, Nahariya, Israel|Rabin Medical Center Beilinson Hospital, Petah Tikva, Israel|Tel Aviv Sourasky Medical Center, Tel Aviv, Israel|Sheba Medical Center, Tel-Hashomer, Israel|Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy|ASST Grande Ospedale Metropolitano Niguarda, Milan, Milano, Italy|Istituto Clinico Humanitas, Rozzano, Milano, Italy|Azienda Ospedaliera Universitaria Careggi SOD Medicina Interna ed Epatologia, Firenze, Italy|ASST Santi Paolo e Carlo, Milano, Italy|Azienda Ospedaliero Universitaria Policlinico Paolo Giaccone, Palermo, Italy|Fondazione Policlinico Tor Vergata, Roma, Italy|Fondazione Policlinico Universitario Agostino Gemelli, Roma, Italy|Pauls Stradins Clinical University Hospital, Riga, Latvia|Consultorio M??dico Dr. Alma Laura Ladron de Guevara, Mexico, Distrito Federal, Mexico|JM Research - Cuernavaca, Cuernavaca, Morelos, Mexico|Investigaciones Medicas Cisneros, Monterrey, Nuevo Leon, Mexico|Consultorio Dra. Maria Sarai Gonzalez Huezo, Metepec, Mexico|Auckland City Hospital, Grafton, Auckland, New Zealand|Middlemore Clinical Trials, Papatoetoe, Auckland, New Zealand|Oslo Universitetssykehus-Ullev??l, Oslo, Norway|Centrum Badan Klinicznych Piotr Napora Lekarze Sp??lka Partnerska, Wroclaw, Dolnoslaskie, Poland|EMC Instytut Medyczny, Wroclaw, Dolnoslaskie, Poland|Wojew??dzki Specjalistyczny Szpital im. dr Wl. Bieganskiego w Lodzi, L??dz, Lodzkie, Poland|Synexus Polska Sp. z o.o. Oddzia?? w ??odzi, ????d??, Lodz, Poland|Szpital Specjalistyczny Nr 1 w Bytomiu, Bytom, Slaskie, Poland|ID Clinic Arkadiusz Pisula, Myslowice, Slaskie, Poland|Synexus Polska Sp z o o Oddzial w Poznaniu, Pozna??, Wielkopolska, Poland|Synexus Polska Sp. z o.o. Oddzial we Wroclawiu, Wroc??aw, Wroclaw, Poland|Synexus Polska Sp. Z o.o. Oddzial w Czestochowie, Czestochowa, Poland|Synexus Polska Sp. z o.o. Oddzial w Gdansku, Gda??sk, Poland|Synexus Polska Sp. z o.o. Oddzial w Gdyni ul., Gdynia, Poland|Synexus SCM Sp. z o.o. Oddzial, Katowice, Poland|Synexus Polska Sp. z o.o. Oddzia?? w Warszawie, Warsaw, Poland|Presa-Ramos, Vila Real, Lordelo, Portugal|Unidade Local de Sa??de do Alto Minho, Viana do Castelo, Portugal|Clinical Research Puerto Rico, San Juan, Puerto Rico|Fundacion de Investigacion De Diego, San Juan, Puerto Rico|Institutul Regional de Gastroenterologie si Hepatologie Prof. Dr. O Fodor, Cluj-Napoca, Cluj, Romania|Clinic Professor Gorbakova, Krasnogorsk, Moscow, Russian Federation|Sklifosovsky Scientific Research Institution of Emergency Care, Moscow, Russian Federation|Moscow Regional Research and Clinical Institute M.F. Vladimirsky, Moscow, Russian Federation|National University Hospital, Singapore, Singapore|Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain|Hospital Universitario Donostia, San Sebastian, Guipuzcoa, Spain|Complejo Hospitalario Torrecardenas, Almeria, Spain|Hospital del Mar, Barcelona, Spain|Hospital Universitari Vall d'Hebr??n, Barcelona, Spain|Hospital General Universitario Gregorio Mara??on, Madrid, Spain|Hospital Universitario Ram??n Y Cajal, Madrid, Spain|Hospital Cl??nico Universitario Virgen de la Victoria, M??laga, Spain|Hospital Universitario Marqu??s de Valdecilla, Santander, Spain|Hospital Universitario Virgen del Rocio, Sevilla, Spain|Hospital Universitario Nuestra Senora de Valme, Sevilla, Spain|Consorci Hospital General Universitari de Val??ncia, Valencia, Spain|Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Spain|Kantonsspital St.Gallen Klinik f??r, St. Gallen, Saint Gallen, Switzerland|Universitaetsspital Bern Inselspital, Bern, Switzerland|Chia-Yi Christian Hospital, Chiayi City, Chiayi, Taiwan|China Medical University Hospital, Taichung, Taichung City, Taiwan|Chang Gung Medical Foundation-LinKou Branch, Taoyuan, Taiwan|University Hospitals Birmingham NHS Foundation Trust, Birmingham, England, United Kingdom|Hull and East Yorkshire Hospitals NHS Trust, Hull, England, United Kingdom|Royal Free London NHS Foundation Trust, London, England, United Kingdom|Kings College Hospital NHS Foundation Trust, London, England, United Kingdom|Chelsea and Westminster Hospital NHS Foundation Trust, London, England, United Kingdom|Luton and Dunstable Hospital NHS Foundation Trust, Luton, England, United Kingdom|Newcastle Upon the Tyne Hospitals, Newcastle, England, United Kingdom|Nottingham Digestive Diseases Biomedical Research Unit, Nottingham, England, United Kingdom|Plymouth Hospitals NHS Trust, Plymouth, England, United Kingdom|Royal Stoke University Hospital, Stoke-on-Trent, England, United Kingdom|St James's University Hospital, Leeds, West Yorkshire, United Kingdom|Synexus Hexham Clinical Research Centre, Hexham, United Kingdom|Synexus Lancashire Clinical Research Centre, Lancaster, United Kingdom|Barts Health NHS Trust The Royal London Hospital, London, United Kingdom|University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom
URL: https://ClinicalTrials.gov/show/NCT03028740

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D068 Cenicriviroc Chemical drug DB11758 CCR2 inhibitor; CCR5 inhibitor Anti-fibrosis Failed in clinical trials Details