| Drug ID: | Drug3 |
|---|---|
| Drug Name: | Ethanol |
| CID: | 702 |
| DrugBank ID: | DB00898 |
| Modality: | Small Molecule |
| Groups: | approved |
| US Approved: | YES |
| Other Approved: | YES |
| Identifier: | NCT03042091 |
| Molecular Formula: | C2H6O |
| Molecular Weight: | 46.07 g/mol |
| Isomeric SMILES: | CCO |
| Synonyms: | ethanol; ethyl alcohol; alcohol; 64-17-5; grain alcohol; Methylcarbinol; Ethyl hydrate; Tecsol; Algrain; Anhydrol |
| Phase 0: | 27 |
| Phase 1: | 72 |
| Phase 2: | 55 |
| Phase 3: | 29 |
| Phase 4: | 49 |
| Description: | A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. [PubChem] |
Molecular Structure
Knowledge Graph
| dtID | CID | Compound Name | Gene ID | Gene Name | Species | PubMed IDs | Action |
|---|---|---|---|---|---|---|---|
| dt12 | 702 | Ethanol | 57498 | KIDINS220 | Mus musculus (house mouse) | 30319688 | Ethanol affects the splicing of KIDINS220 mrna|ethanol results in increased expression of KIDINS220 mRNA |
| dt13 | 702 | Ethanol | 63971 | KIF13A | Mus musculus (house mouse) | 30319688 | Ethanol results in increased expression of KIF13A mrna|ethanol affects the splicing of KIF13A mRNA |
| dt14 | 702 | Ethanol | 23303 | KIF13B | Mus musculus (house mouse) | 30319688 | Ethanol results in increased expression of KIF13B mRNA |
| dt15 | 702 | Ethanol | 81930 | KIF18A | Mus musculus (house mouse) | 30517762 | [carbon tetrachloride co-treated with ethanol] results in increased expression of KIF18A mRNA |
| dt16 | 702 | Ethanol | 547 | KIF1A | Mus musculus (house mouse) | 30319688 | Ethanol results in increased expression of KIF1A mrna|ethanol affects the splicing of KIF1A mRNA |
| dt17 | 702 | Ethanol | 547 | KIF1A | Mus musculus (house mouse) | 29018328 | Ethanol results in decreased expression of KIF1A mRNA |
| dt18 | 702 | Ethanol | 566766 | kif1ab | Danio rerio (zebrafish) | 29361514 | Ethanol results in increased expression of KIF1AB mRNA |
| dt19 | 702 | Ethanol | 23095 | KIF1B | Mus musculus (house mouse) | 30319688 | Ethanol results in increased expression of KIF1B mrna|ethanol affects the expression of and affects the splicing of KIF1B mRNA |
| dt20 | 702 | Ethanol | 10749 | KIF1C | Mus musculus (house mouse) | 30319688 | Ethanol results in increased expression of KIF1C mRNA |
| dt21 | 702 | Ethanol | 55605 | KIF21A | Mus musculus (house mouse) | 30319688 | Ethanol affects the splicing of KIF21A mRNA |
- No data available
Phase Distribution
Phase Description
- Phase 0: Exploratory trials to assess drug behavior in humans
- Phase 1: Safety trials to determine safe dosage range
- Phase 2: Efficacy trials to evaluate therapeutic effects
- Phase 3: Large-scale trials to confirm efficacy and safety
- Phase 4: Post-marketing surveillance for long-term safety and efficacy
| Trial ID | Title | Phase | Status | Sponsor | Indications | Interventions | |
|---|---|---|---|---|---|---|---|
| NCT00928733 | Effects of Ethanol on Intestinal Permeability and Integrity | NA | COMPLETED | Maastricht University Medical Center | Healthy | DEVICE: Gastroduodenoscopy- Intraduodenal intubat… | Details |
| NCT06432569 | Evaluation of Butyrate and Palmitoylethanolamide in IBS Patients (B/P3_1) | NA | COMPLETED | University of Padova | Irritable Bowel Syndrome With Diarrhea | DIETARY_SUPPLEMENT: ButirBioma + PeaBioma|DIETARY… | Details |
| NCT05867693 | Palmitoylethanolamide and Polydatin in Pediatric Irritable Bowel Syndrome | NA | UNKNOWN | University of Roma La Sapienza | Irritable Bowel Syndrome | DIETARY_SUPPLEMENT: palmithoylethanolamide/polyda… | Details |
| NCT05164861 | Safety and Efficacy of Non-alcoholic Beverage Based on Kombucha in Patients With Constipations | NA | COMPLETED | Vasily Isakov | Irritable Bowel Syndrome With Constipation|Consti… | DIETARY_SUPPLEMENT: kombucha-based beverage | Details |
| NCT07086989 | Cardiovascular Risk in Children With Chronic Conditions Study | NULL | RECRUITING | Semmelweis University | Kidney Transplant|Familial Hypercholesterolaemia|… | None | Details |
| NCT04328259 | Prevalance of non_ Alcoholic Fatty Liver Diseases in Patient With Inflammatory Bowel Diseases Attending Assiut University Hospitals | NULL | UNKNOWN | Assiut University | Inflammatory Bowel Disease Patients | None | Details |
| NCT04306939 | Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study | NULL | SUSPENDED | University of Pittsburgh | Chronic Pancreatitis|Inflammatory Bowel Diseases|… | OTHER: venipuncture|BEHAVIORAL: Questionnaires|OT… | Details |
| NCT04014413 | Safety and Efficacy of Fecal Microbiota Transplantation | NA | RECRUITING | Chinese University of Hong Kong | Crohn Disease|Ulcerative Colitis|Celiac Disease|I… | PROCEDURE: Fecal Microbiota Transplantation | Details |
| NCT06939569 | An Observational Study of Inflammatory Bowel Disease (IBD) Patients With Non-alcoholic Fatty Liver Disease (NAFLD) | NULL | RECRUITING | Shanghai East Hospital | Inflammatory Bowel Disease (IBD)|Metabolic Dysfun… | None | Details |
| NCT03329885 | A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis | PHASE1|PHASE2 | TERMINATED | Bristol-Myers Squibb | Rheumatoid Arthritis|Psoriasis|Ankylosing Spondyl… | DRUG: BMS-986251|OTHER: Placebo | Details |
| NCT06814600 | Prevalence of Non-Alcoholic Fatty Liver Disease in Inflammatory Bowel Disease Patients | NULL | RECRUITING | Centre Hospitalier Universitaire Saint Pierre | NAFLD|Inflammatory Bowel Diseases|Steatosis|Fibro… | DIAGNOSTIC_TEST: Transient elastometry | Details |
| NCT01793168 | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford | NULL | RECRUITING | Sanford Health | Rare Disorders|Undiagnosed Disorders|Disorders of… | None | Details |
| NCT01709201 | Reducing Problematic Substance Use in Youth With Chronic Medical Conditions | NA | WITHDRAWN | Boston Children's Hospital | Alcohol Abuse|Drug Abuse | BEHAVIORAL: Brief Intervention | Details |
| NCT01705522 | Multimodal Approach in IBD Patients | NULL | UNKNOWN | Clinical Hospital Colentina | Ulcerative Colitis|Crohn's Disease|Nonalcoholic F… | None | Details |
| NCT01476995 | Prognostic Indicators as Provided by the EPIC ClearView | NULL | COMPLETED | Epic Research & Diagnostics, Inc. | Coronary Artery Disease|Congestive Heart Failure|… | None | Details |
| JPRN-UMIN000045216 | Development of intestinal environment evaluation system by integrated analysis of intestinal microbiota research database - Development of intestinal environment evaluation system by integrated analysis of intestinal microbiota research database | NULL | Recruiting | Department for Medical Innovation and Translational Medical Science, Kyoto Prefectural University of Medicine | healthy individuals without diseases, inflammator… | NULL | Details |
| JPRN-UMIN000019486 | Enterobacterial analysis for the precise medical care (precision medicine) for diabetes, non-alcoholic lipid liver disease / non-alcoholicity fat hepatitis, inflammatory bowel disease, and irritable bowel syndrome. - Enterobacterial analysis for the preci | NULL | Recruiting | Kyoto Prefectural University of Medicine | diabetes, non-alcoholic lipid liver disease / non… | NULL | Details |
| DRKS00004935 | Attitudes towards eCommunication.in treatment of chronically ill patients . - EC@T | NULL | Recruiting | Uniklinikum Freiburg, Institut f Qualitsmanagement und Sozialmedizin | Chronic back pain.Chronic ischemic heart disease.… | Group 1: The EC@T-project consists of three subst… | Details |
| ACTRN12618000122257 | The effects of a multidisciplinary Gastroenterology and Hepatology Integrated Care Clinic approach in patients with chronic gastrointestinal disorders: a randomised controlled trial. | NULL | Recruiting | Princess Alexandra Hospital | Nonalcoholic Fatty Liver Disease;Nonalcoholic Ste… | The Department of Gastroenterology and Hepatology… | Details |
| ACTRN12609000913279 | Does cognitive-behavioural therapy (CBT) improve outcomes in inflammatory bowel disease (IBD)? A pilot randomised controlled trial | NULL | Not Recruiting | Royal Adelaide Hospital | Inflammatory bowel disease (IBD); Inflammatory bo… | Preliminary screening of interested subjects will… | Details |
| Disease ID | Disease Name | Definition | Category | Related Drugs | Mechanism | |
|---|---|---|---|---|---|---|
| No data available | ||||||
| Strategy ID | Therapeutic Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||
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