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FXR deletion attenuates intestinal barrier dysfunction in murine acute intestinal inflammation

Publication Year: 2024 Source: Am J Physiol Gastrointest Liver Physiol PMID: 38860296

No Abstract

Glycyrol Relieves Ulcerative Colitis by Promoting the Fusion of ZO-1 with the Cell Membrane through the Enteric Glial Cells GDNF/RET Pathway

Publication Year: 2024 Source: J Agric Food Chem PMID: 38860840

No Abstract

Colonocyte keratins stabilize mitochondria and contribute to mitochondrial energy metabolism

Publication Year: 2024 Source: Am J Physiol Gastrointest Liver Physiol PMID: 38860856

No Abstract

Cu,Zn,I-Doped Carbon Dots with Boosted Triple Antioxidant Nanozyme Activity for Treatment of DSS-Induced Colitis

Publication Year: 2024 Source: ACS Appl Mater Interfaces PMID: 38860867 DOI: 10.1021/acsami.4c03627

Nanozyme-mediated antioxidative therapy is a promising star for treating a myriad of important diseases through eliminating excessive reactive oxygen species (ROS) such as O(2)(.-) and H(2)O(2), a critical mechanism for inflammatory bowel disease (IBD). This work provides a high biocompatibility iodine-copper-zinc covalent doped carbon dots (Cu,Zn,I-CDs) with the catalase (CAT)-, …

Melanin Nanoparticle-Modified Probiotics for Targeted Synergistic Therapy of Ulcerative Colitis

Publication Year: 2024 Source: ACS Appl Mater Interfaces PMID: 38861025

No Abstract

Course of Uveitis in Patients with Ankylosing Spondylitis during the Interleukin17 Inhibitors Therapy

Publication Year: 2024 Source: Dokl Biochem Biophys PMID: 38861150 DOI: 10.1134/S1607672924700868

Biological disease-modifying antirheumatic drugs (bDMARDs) can have different effects on various clinical manifestations of ankylosing spondylitis (AS). Data on the effects of interleukin 17 inhibitors (IL17-i) on uveitis in AS continue to accumulate. Objective: to evaluate the effect of IL17-i therapy on the course of uveitis in AS. The study …

A case of ulcerative colitis with a variety of autoimmune diseases including ankylosing spondylitis, type 2 autoimmune pancreatitis, and primary sclerosing cholangitis

Publication Year: 2024 Source: Clin J Gastroenterol PMID: 38861196

No Abstract

A Structure-Based Design Strategy with Pyrazole-Pyridine Derivatives Targeting TNFα as Anti-Inflammatory Agents: E-Pharmacophore, Dynamic Simulation, Synthesis and In Vitro Evaluation

Publication Year: 2024 Source: Chem Biodivers PMID: 38861376

No Abstract

Vibrio MARTX toxin processing and degradation of cellular Rab GTPases by the cytotoxic effector Makes Caterpillars Floppy

Publication Year: 2024 Source: Proc Natl Acad Sci U S A PMID: 38861595

No Abstract

Rapamycin promotes the intestinal barrier repair in ulcerative colitis via the mTOR/PBLD/AMOT signaling pathway

Publication Year: 2024 Source: Biochim Biophys Acta Mol Basis Dis PMID: 38862095

No Abstract

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