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Role of gastroenterologists and healthcare providers in promoting COVID-19 immunization among individuals with inflammatory bowel disease: A systematic review and meta-analysis on a global scale

Publication Year: 2024 Source: Hum Vaccin Immunother PMID: 38755111 DOI: 10.1080/21645515.2024.2349319

Individuals with Inflammatory Bowel Disease (IBD) are more susceptible to experiencing severe complications of COVID-19 if infected. Nevertheless, sub-optimal immunization rates have been reported among these patients. Our study aims to assess COVID-19 VH among a global population of patients with IBD and to investigate the role of healthcare professionals, …

Is it "all in the bag?" Multidisciplinary perspectives on ostomy surgery in pediatric IBD across the ImproveCareNow network

Publication Year: 2024 Source: JPGN Rep PMID: 38756109 DOI: 10.1002/jpr3.12044

OBJECTIVES: Pediatric inflammatory bowel disease (IBD) is a chronic illness with various treatments, including ostomy surgery. Ostomy-related medical decision-making (MDM) is complex for multidisciplinary healthcare professionals (HCPs). This study sought to understand national multidisciplinary HCPs' perceptions about pediatric IBD ostomy surgery in the United States. METHODS: This cross-sectional REDCap survey …

Mucosal prolapse syndrome mimicking Peutz-Jeghers syndrome in a pediatric patient

Publication Year: 2024 Source: JPGN Rep PMID: 38756112

No Abstract

Collagenous gastritis with elevated fecal calprotectin in a pediatric patient

Publication Year: 2024 Source: JPGN Rep PMID: 38756119

No Abstract

Cause or effect? Undetectable vitamin D in a patient with Crohn's disease

Publication Year: 2024 Source: JPGN Rep PMID: 38756124

No Abstract

Rescue therapy with upadacitinib in medically refractory pediatric ulcerative colitis

Publication Year: 2024 Source: JPGN Rep PMID: 38756133 DOI: 10.1002/jpr3.12067

Approved options for advanced therapy in pediatric inflammatory bowel disease (IBD) are limited. Although Janus kinase (JAK) inhibitors are approved in adult IBD, their benefit in pediatric populations is not yet delineated. We present a 13-year-old female patient with ulcerative colitis (UC) refractory to numerous therapies and courses of prednisone …

ELMO1 ameliorates intestinal epithelial cellular senescence via SIRT1/p65 signaling in inflammatory bowel disease-related fibrosis

Publication Year: 2024 Source: Gastroenterol Rep (Oxf) PMID: 38756351 DOI: 10.1093/gastro/goae045

BACKGROUND: Intestinal fibrosis is a common complication in inflammatory bowel disease (IBD), which still lacks of reliable markers and therapeutic options. Cellular senescence has been considered an important mechanism of intestinal fibrosis, but the underlying molecular link remains elusive. METHODS: Tissues were stained using alpha-smooth muscle actin (alpha-SMA), fibronectin, and …

Intestinal microflora promotes Th2-mediated immunity through NLRP3 in damp and heat environments

Publication Year: 2024 Source: Front Immunol PMID: 38756775

No Abstract

Colon-targeted oral nanoliposomes loaded with psoralen alleviate DSS-induced ulcerative colitis

Publication Year: 2024 Source: Biomater Sci PMID: 38757193

No Abstract

Associations Between Brain Morphology, Inflammatory Markers, and Symptoms of Fatigue, Depression, or Anxiety in Active and Remitted Crohn's Disease

Publication Year: 2024 Source: J Crohns Colitis PMID: 38757201 DOI: 10.1093/ecco-jcc/jjae078

BACKGROUND: Fatigue and psychosocial impairments are highly prevalent in IBD, particularly during active disease. Disturbed brain-gut interactions may contribute to these symptoms. This study examined associations between brain structure, faecal calprotectin, and symptoms of fatigue, depression, and anxiety in persons with Crohn's disease [CD] in different disease states. METHODS: In …

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