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Trends in Targeted Therapy Usage in Inflammatory Bowel Disease: TRENDY Study of ENEIDA
Publication Year: 2024 Source: Pharmaceutics PMID: 38794292 DOI: 10.3390/pharmaceutics16050629
Markers that allow for the selection of tailored treatments for individual patients with inflammatory bowel diseases (IBD) are yet to be identified. Our aim was to describe trends in real-life treatment usage. For this purpose, patients from the ENEIDA registry who received their first targeted IBD treatment (biologics or tofacitinib) …
Effects of Mediterranean Diet, Curcumin, and Resveratrol on Mild-to-Moderate Active Ulcerative Colitis: A Multicenter Randomized Clinical Trial
Publication Year: 2024 Source: Nutrients PMID: 38794742
No Abstract
Gut Epithelial Barrier Function is Impacted by Hyperglycemia and Secondary Bile Acids in Vitro: Possible Rescuing Effects of Specific Pectins
Publication Year: 2024 Source: Mol Nutr Food Res PMID: 38794856 DOI: 10.1002/mnfr.202300910
Gut epithelial barrier disruption is commonly observed in Western diseases like diabetes and inflammatory bowel disease (IBD). Enhanced epithelial permeability triggers inflammatory responses and gut microbiota dysbiosis. Reduced bacterial diversity in IBD affects gut microbiota metabolism, altering microbial products such as secondary bile acids (BAs), which potentially play a role …
Dried fruit intake can lower the risk of ulcerative colitis: evidence from a Mendelian randomization study
Publication Year: 2024 Source: Asia Pac J Clin Nutr PMID: 38794983
No Abstract
Evaluation of stem-cell therapies in companion animal disease models: a concise review (2015-2023)
Publication Year: 2024 Source: Stem Cells PMID: 38795363
No Abstract
Is religiosity/spirituality in patients with Crohn's disease important to their quality of life?
Publication Year: 2024 Source: Clinics (Sao Paulo) PMID: 38795523 DOI: 10.1016/j.clinsp.2024.100389
The authors aim to study Religiosity/Spirituality (R/S) and Quality of Life (QoL) in patients with Crohn's disease and their correlation with the disease phenotypes. METHODS: Prospective cross-sectional cohort study with 151 consecutive patients enrolled from March 2021 to October 2021 at the Colorectal IBD Outpatient of Hospital das Clinicas da …
Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron
Publication Year: 2024 Source: Int Immunopharmacol PMID: 38795598
No Abstract
Psoriasis Comorbidities and Their Treatment Impact
Publication Year: 2024 Source: Dermatol Clin PMID: 38796272
No Abstract
Atox1 regulates macrophage polarization in intestinal inflammation via ROS-NLRP3 inflammasome pathway
Publication Year: 2024 Source: J Transl Med PMID: 38796413 DOI: 10.1186/s12967-024-05314-4
BACKGROUND: Inflammation and oxidative stress play an important role in the pathophysiology of inflammatory bowel disease (IBD). This study aimed to explore the effects of copper chaperone Antioxidant-1 (Atox1) on macrophages in a mouse model of intestinal inflammation. METHODS: A mouse model of TNBS-induced colitis was established and verified using …
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