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Recent advances in the therapeutic applications of selenium nanoparticles

Publication Year: 2024 Source: Mol Biol Rep PMID: 38796570 DOI: 10.1007/s11033-024-09598-z

Selenium nanoparticles (SeNPs) are an appealing carrier for the targeted delivery. The selenium nanoparticles are gaining global attention because of the potential therapeutic applications in several diseases e.g., rheumatoid arthritis (RA), inflammatory bowel disease (IBD), asthma, liver, and various autoimmune disorders like psoriasis, cancer, diabetes, and a variety of infectious …

The implementation of an inflammatory bowel disease-specific enhanced recovery after surgery protocol: an observational cohort study

Publication Year: 2024 Source: Tech Coloproctol PMID: 38796600 DOI: 10.1007/s10151-024-02933-3

BACKGROUND: The implementation of Enhanced Recovery After Surgery (ERAS) protocols has resulted in improved postoperative outcomes in colorectal cancer surgery. The evidence regarding feasibility and impact on outcomes in surgery for inflammatory bowel disease (IBD) is limited. METHODS: We performed a retrospective observational cohort study, comparing patient trajectories before and …

Polygenic risk scores for autoimmune related diseases are significantly different in cancer exceptional responders

Publication Year: 2024 Source: NPJ Precis Oncol PMID: 38796637

No Abstract

Spontaneous bilateral avascular necrosis of knees and hip leading to early bilateral total hip arthroplasty: a case report of an 18-year-old man recently diagnosed with Crohn's disease

Publication Year: 2024 Source: Clin J Gastroenterol PMID: 38796798 DOI: 10.1007/s12328-024-01987-y

Avascular necrosis (AVN) is linked to considerable morbidity, resulting in severe pain and functional impairment. Herein, for the first time, we reported an 18-year-old patient with Crohn's disease during the remission phase under Azathioprine therapy who presented with articular pain. Although no underlying risk factors, the patient was diagnosed with …

Inpatient Infliximab Biosimilar Cost-Savings: Cost Analysis of Inpatient Treatment with Originator Infliximab (Remicade™) versus Biosimilar Infliximab (Renflexis™) for Acute Severe Ulcerative Colitis

Publication Year: 2024 Source: Dig Dis PMID: 38797170

No Abstract

Recent progress in engineered extracellular vesicles and their biomedical applications

Publication Year: 2024 Source: Life Sci PMID: 38797364

No Abstract

Da-yuan-yin decoction alleviates ulcerative colitis by inhibiting complement activation, LPS-TLR4/NF-κB signaling pathway and NET formation

Publication Year: 2024 Source: J Ethnopharmacol PMID: 38797378

No Abstract

Beneficial effects of oxymatrine from Sophora flavescens on alleviating Ulcerative colitis by improving inflammation and ferroptosis

Publication Year: 2024 Source: J Ethnopharmacol PMID: 38797379

No Abstract

Physiologically-based pharmacokinetic modeling to predict the exposure and provide dosage regimens of Ustekinumab in pediatric patients with inflammatory bowel disease

Publication Year: 2024 Source: Eur J Pharm Sci PMID: 38797440 DOI: 10.1016/j.ejps.2024.106807

Ustekinumab (UST), a fully human immunoglobulin G1 kappa monoclonal antibody, exhibiting high affinity for the p40 subunit shared by IL-12 and IL-23, which play key roles in the pathogenesis of inflammatory bowel disease (IBD). By scaling the physiologically-based pharmacokinetic modeling (PBPK) model of UST in adult patients with IBD, we …

MMX mesalamine: A modern twist on a classic treatment

Publication Year: 2024 Source: Dig Liver Dis PMID: 38797598

No Abstract

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