Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Clinical characteristics and surgical management of ileal strictures caused by ischemic enteritis: a report of three cases
Publication Year: 2025 Source: J Surg Case Rep PMID: 40463706
Ischemic enteritis (IE) is characterized by blood flow insufficient to meet metabolic demands. The incidence of IE is increasing owing to the aging population and advancements in radiographic and endoscopic diagnostics. Many patients eventually require surgical management, indicating an irreversible and progressive pathology. Therefore, clear definitions, early diagnosis, and tailored …
Addressing controversy in Fusobacterium nomenclature: what exactly does "F. nucleatum" refer to?
Publication Year: 2025 Source: Gut Microbes PMID: 40464118
The F. nucleatum group (sensu lato) is historically composed of four subspecies (F. nucleatum subsp. animalis, F. nucleatum subsp. nucleatum, F. nucleatum subsp. polymorphum, F. nucleatum subsp. vincentii). Although F. nucleatum sensu lato members are typically associated with oral disease, they have recently been shown to disseminate to the gastrointestinal …
Gene-Environment Interactions in Inflammatory Bowel Disease: A Systematic Review of Human Epidemiologic Studies
Publication Year: 2025 Source: J Crohns Colitis PMID: 40464295 DOI: 10.1093/ecco-jcc/jjaf061
BACKGROUND AND AIMS: Complex gene-environment interaction (GXE) for inflammatory bowel disease (IBD) remains elusive. This systematic review aims to summarize the current evidence of GXE in IBD. METHODS: PubMed, EMBASE, Web of Science, and Scopus were systematically searched from inception through April 30, 2024, to identify publications examining the interaction …
Biosynthesis of Melanin with Engineered Probiotics for Oral Treatment of Ulcerative Colitis
Publication Year: 2025 Source: ACS Nano PMID: 40464444
Ulcerative colitis (UC) is a chronic intestinal inflammation characterized by immune overactivity and gut microbiota imbalance, leading to oxidative stress and inflammation. New therapeutics are required because existing ones are frequently unsuccessful and have long-term adverse effects. The research aims to manage oxidative stress and restore gut microbiota balance. The …
Implications of gut microbiota-mediated epigenetic modifications in intestinal diseases
Publication Year: 2025 Source: Gut Microbes PMID: 40464639 DOI: 10.1080/19490976.2025.2508426
Intestinal diseases are highly prevalent, affecting millions worldwide and significantly contributing to global morbidity. The treatment of complex disorders, such as inflammatory bowel disease (IBD) and colorectal cancer (CRC), remains challenging due to multifactorial etiologies, diverse patient responses, and the limitations of current therapeutic strategies. Although the gut microbiota clearly …
Comment on a Risk Stratification Tool for Relapse After Intravenous-to-Subcutaneous Switching of Infliximab in Patients With Inflammatory Bowel Diseases
Publication Year: 2025 Source: Am J Gastroenterol PMID: 40464796
No Abstract
Interleukin-23 Inhibitors for Inflammatory Bowel Disease: Pivotal Trials and Practical Considerations
Publication Year: 2025 Source: Curr Gastroenterol Rep PMID: 40465057
PURPOSE OF REVIEW: This review summarizes the literature on IL-23 inhibitors for inflammatory bowel disease and the role of these agents in clinical practice. RECENT FINDINGS: The last decade has seen several pivotal trials investigating IL-23 inhibitors. These agents are effective in inducing and maintaining remission of moderate-to-severe inflammatory bowel …
Therapeutic Potential of Probiotics: A Review of Their Role in Modulating Inflammation
Publication Year: 2025 Source: Probiotics Antimicrob Proteins PMID: 40465090 DOI: 10.1007/s12602-025-10609-z
Probiotics are characterized as beneficial live microorganisms which, when consumed in sufficient quantities, provide measurable health advantages to the host organism. These beneficial microbes, primarily comprising specific strains of bacteria and yeasts, play a critical role in restoring and maintaining gut microbiota homeostasis, enhancing gastrointestinal health, strengthening immune responses, and …
Advancements in the prevention and management of postoperative Crohn's disease recurrence
Publication Year: 2025 Source: Expert Rev Gastroenterol Hepatol PMID: 40465476
INTRODUCTION: Postoperative recurrence of Crohn's disease after surgery remains common. The aim of this article is to present a comprehensive review of recent advancements in postoperative prognostication, surveillance, and the therapeutic prophylaxis. AREAS COVERED: Reduction in postoperative recurrence risk is a multifactorial process requiring risk stratification, prophylactic therapeutics, and postoperative …
Severity of acute SARS-CoV-2 infection and risk of new-onset autoimmune disease: A RECOVER initiative study in nationwide U.S. cohorts
Publication Year: 2025 Source: PLoS One PMID: 40465573
SARS-CoV-2 infection has been associated with increased autoimmune disease risk. Past studies have not aligned regarding the most prevalent autoimmune diseases after infection, however. Furthermore, the relationship between infection severity and new autoimmune disease risk has not been well examined. We used RECOVER's electronic health record (EHR) networks, N3C, PCORnet, …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide