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Hit the road JAK: is there still hope left for TYK2 inhibition in IBD?
Publication Year: 2025 Source: J Crohns Colitis PMID: 40468675 DOI: 10.1093/ecco-jcc/jjaf088
No Abstract
Expression of serum HMGB1, SAA, and TSGF in patients with colon cancer and the value of prognostic assessment
Publication Year: 2025 Source: Cancer Biomark PMID: 40468720 DOI: 10.1177/18758592241297848
Objective: To investigate the expression of serum high mobility group protein 1 (HMGB1), amyloid A (SAA), and tumor-specific growth factor (TSGF) in patients with colon cancer (CRC) and the value of prognostic assessment. Methods: Sixty cases of CRC patients admitted to our hospital from January 2018 to December 2020 were …
Comparative Efficacy of Different Targeted Therapies in Patients With Moderate-to-Severe Ulcerative Colitis: Systematic Review/Network Meta-Analysis and Mechanistic Overview
Publication Year: 2025 Source: Pharmacol Res Perspect PMID: 40468857
Ongoing evaluations of targeted therapies for moderate-to-severe ulcerative colitis (UC) continue to unfold, with the emergence of novel drugs. However, head-to-head trials comparing these therapies are still lacking. The aim of this study is to investigate the therapeutic effects of targeted therapies in moderate-to-severe UC. The Cochrane Library, Web of …
The Association of Inflammatory Bowel Disease and Eosinophilic Esophagitis: A Systematic Review and Meta-analysis
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 40468892 DOI: 10.1093/ibd/izaf095
BACKGROUND: The association between inflammatory bowel disease (IBD) and eosinophilic esophagitis (EoE) remains unclear. We aimed to perform a systematic review and meta-analysis on the association between EoE, IBD, and other immune-mediated inflammatory diseases. METHODS: A systematic literature search was conducted in Ovid MEDLINE, Ovid Embase, and the Cochrane Central …
Diagnostic Challenges in EBV-Associated B-Cell Lymphoproliferative Disorder
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 40468896 DOI: 10.1093/ibd/izaf111
No Abstract
Gut microbiota-driven pathogenic Th17 cells mediated autoimmune epididymo-orchitis in a mouse model of colitis
Publication Year: 2025 Source: iScience PMID: 40469115 DOI: 10.1016/j.isci.2025.112508
No Abstract
Insights into the status of the quality of nursing care in patients with inflammatory bowel disease: A nationwide survey (The MAPEA Project)
Publication Year: 2025 Source: Gastroenterol Hepatol PMID: 40378951 DOI: 10.1016/j.gastrohep.2025.502464
BACKGROUND AND AIMS: This study aimed to provide a comprehensive nationwide assessment of the status of nursing management in inflammatory bowel disease (IBD). METHODS: A nationwide observational cross-sectional survey study was conducted. Nurses involved in the care of patients with IBD completed the 90-item Nursing Care Quality in IBD Assessment …
DIAGNOSIS AND MANAGEMENT OF UPPER GASTROINTESTINAL INVOLVEMENT IN ADULT PATIENTS WITH CROHN'S DISEASE: A SYSTEMATIC REVIEW
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 40378982 DOI: 10.1016/j.cgh.2025.03.024
BACKGROUND: The diagnosis and management of ileocolonic Crohn's disease (CD) are well established. In contrast, standardized guidance pertaining to the diagnosis and management of upper gastrointestinal CD (UGICD) is lacking, despite its potentially severe consequences. OBJECTIVE: This comprehensive systematic review describes the prevalence, clinical presentation and medical and surgical management …
Outcomes of Allogeneic Hematopoietic Stem Cell Transplant in Monogenic Inflammatory Bowel Disease
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 40378986 DOI: 10.1016/j.cgh.2025.03.018
BACKGROUND & AIMS: Monogenic inflammatory bowel disease (IBD) can result in inborn errors of immunity and intestinal epithelial cell dysfunction, more commonly seen in patients with very early onset IBD (VEO-IBD). Hematopoietic stem cell transplant (HSCT) has emerged as an effective treatment for a subset of patients with monogenic IBD. …
Long-term Benefits of Resilience-based Integrated Care: Reduced Unplanned Care, Opioid, and Steroid Use in the GRITT-IBD Study
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 40378988 DOI: 10.1016/j.cgh.2025.03.019
No Abstract
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