Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Diagnostic Challenges of Upper Gastrointestinal Tract Crohn's Disease
Publication Year: 2025 Source: Cureus PMID: 40376323
Crohn's disease (CD) is a chronic inflammatory disorder that commonly affects the distal small bowel and proximal large bowel. However, it can involve any part of the gastrointestinal tract (GIT), including the upper GIT. However, upper GIT involvement is often overlooked due to the limited use of upper gastrointestinal (UGI) …
Secondary hemophagocytic lymphohistiocytosis in a 5-month-old infant with IBD post-COVID-19: a case report
Publication Year: 2025 Source: Front Pediatr PMID: 40376626 DOI: 10.3389/fped.2025.1536066
BACKGROUND: COVID-19 is known to induce cytokine storms and inappropriate cytotoxic immune responses. Hemophagocytic lymphohistiocytosis (HLH) is an underrecognized condition due to a hyperinflammatory syndrome characterized by fulminant hypercytokinemia with a high mortality burden. Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induced secondary HLH during and post-infection have …
Spondyloarthritis features in IBD patients: prevalence, referral trends and clinical implications. A questionnaire-based study
Publication Year: 2025 Source: Scand J Gastroenterol PMID: 40376944 DOI: 10.1080/00365521.2025.2504076
OBJECTIVES: This study examines the prevalence of spondyloarthritis (SpA) features in patients with inflammatory bowel disease (IBD) and their rates of referral to rheumatologists. MATERIAL AND METHODS: A questionnaire was administered to 2087 IBD patients (>/=18 years) in Sweden, assessing demographics, medications and SpA features based on the ASAS and …
Expression Profile of Serum CircFUNDC1 and CircUHRF1 Can Differentiate Between Colorectal Cancer and Inflammatory Bowel Diseases (Ulcerative Colitis and Crohn's Disease)
Publication Year: 2025 Source: J Clin Lab Anal PMID: 40376950 DOI: 10.1002/jcla.70039
BACKGROUND: Colorectal cancer (CRC) is a worldwide burden. Circular RNAs are promising biomarkers for diagnosing and prognosis of CRC. OBJECTIVE: To investigate the possible association of sera levels of CircFUNDC1 and CircUHRF1 expression with predisposition and clinicopathological findings in CRC, ulcerative colitis (UC), and Crohn's disease (CD) in Egyptian patients. …
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress
Publication Year: 2025 Source: Elife PMID: 40377187 DOI: 10.7554/eLife.89862
A wide variety of human diseases are associated with loss of microbial diversity in the human gut, inspiring a great interest in the diagnostic or therapeutic potential of the microbiota. However, the ecological forces that drive diversity reduction in disease states remain unclear, rendering it difficult to ascertain the role …
Drinking Water Temperature Impacts the Pathogenesis of DSS-Induced Ulcerative Colitis by Regulating Intestinal Barrier Function and Remodeling the Gut Microbiota Composition
Publication Year: 2025 Source: FASEB J PMID: 40377203
Environmental factors, including poor dietary habits and unhealthy drinking patterns, contribute to ulcerative colitis (UC). While the relationship between diet-related malnutrition and UC has been extensively explored, the impact of drinking water temperature remains largely overlooked, prompting us to investigate its influence on UC pathogenesis and explore the underlying mechanisms. …
cGAS-STING Pathway's Impact on Intestinal Barrier
Publication Year: 2025 Source: J Gastroenterol Hepatol PMID: 40377214
Intestinal inflammation and increased permeability have been linked to metabolic dysregulation in patients with compromised intestinal barrier function. Among the pathways, garnering attention is the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway. Upon binding to double-stranded DNA (dsDNA), cGAS catalyzes the conversion of ATP and GTP into cyclic GMP-AMP …
Gender-Affirming Hormone Therapy and Risk of Inflammatory Bowel Disease Flare in Transgender and Gender Diverse Adults
Publication Year: 2025 Source: Am J Gastroenterol PMID: 40377244 DOI: 10.14309/ajg.0000000000003543
INTRODUCTION: Little is known about the impact of gender-affirming hormone therapy (GAHT) on transgender and gender diverse adults with inflammatory bowel disease (IBD). The primary aim was to evaluate the incidence of IBD flare in the year before and after GAHT initiation. METHODS: A retrospective study across 5 IBD centers. …
[Use of a combined form of prostate extract and alpha-adrenoblocker in patients after transurethral resection of the prostate]
Publication Year: 2025 Source: Urologiia PMID: 40377578
BACKGROUND: Prostate extract has pronounced anti-inflammatory and anti-androgenic properties, which contribute to a reduction in the volume of the prostate and an improvement in urination. Alpha-adrenoblockers, in turn, exert a relaxing effect on the smooth muscles of the bladder and prostate, thereby facilitating the urination. The combined use of these …
PCR-based stool testing for enteric infections in flares of inflammatory bowel disease: Is more data worth the cost?
Publication Year: 2025 Source: Indian J Gastroenterol PMID: 40377862
No Abstract
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide