Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Periodontitis is associated with increased disease activity in a Swedish cohort of patients with inflammatory bowel disease
Publication Year: 2025 Source: Scand J Gastroenterol PMID: 40515581 DOI: 10.1080/00365521.2025.2517217
BACKGROUND: Periodontitis and inflammatory bowel disease (IBD) are chronic, progressive inflammatory diseases with shared aetiopathogenetic mechanisms. Research suggests that IBD patients are at increased risk of developing periodontitis, which may, in turn, exacerbate IBD activity and disability. This study examines whether periodontitis is associated with increased IBD activity, severity, disability …
Study on rTMS's therapeutic effect on constipation in Parkinson's disease via the brain-gut axis theory
Publication Year: 2025 Source: Neurol Res PMID: 40515608
OBJECTIVE: This study investigates the therapeutic effects of repetitive transcranial magnetic stimulation (rTMS) on constipation in Parkinson's disease (PD) patients, based on the brain-gut axis theory. METHODS: Fifty-eight PD patients with constipation (aged 52-68 years) were randomly assigned to the treatment group (receiving high-frequency 10 hz rTMS targeting the left …
A scoping review on reporting of methods in DSS colitis mouse models
Publication Year: 2025 Source: Lab Anim PMID: 40515727 DOI: 10.1177/00236772251331677
Inflammatory bowel diseases (IBDs) are a major health burden, and incidence as well as prevalence have increased over the last decades. Colitis animal models are used to explore the underlying pathogenesis of and therapeutic options for IBD. Since the reporting of specific aspects of colitis studies using mice has been …
Patients with Crohn's Disease and Ileostomy Can Respond to Upadacitinib
Publication Year: 2025 Source: Dig Dis Sci PMID: 40515784
BACKGROUND: Recent studies have established a role for Janus kinase (JAK) inhibitors in the management of patients with inflammatory bowel disease. However, these studies excluded patients with an ileostomy. AIM: We sought to evaluate the clinical response of patients with Crohn's disease (CD) and ileostomy who were treated with upadacitinib. …
Managing Pouchitis: Where do Antibiotics End, and Advanced Therapies Begin?
Publication Year: 2025 Source: Curr Gastroenterol Rep PMID: 40515946
PURPOSE OF REVIEW: Pouchitis is a common complication in patients with ulcerative colitis who undergo total colectomy with ileal pouch anal anastomosis that presents a challenge to clinicians. In the article, we review the management of patients with pouchitis based on best available evidence. RECENT FINDINGS: Pouchitis can be practically …
Increased Allergic Rhinitis Prevalence and Symptom Severity in Patients With Irritable Bowel Syndrome
Publication Year: 2025 Source: Neurogastroenterol Motil PMID: 40516111
BACKGROUND: Patients with irritable bowel syndrome (IBS) have an increased risk of developing both airway and allergic diseases. However, the relationship between allergic rhinitis (AR), one of the most common chronic upper airway inflammatory diseases, and IBS remains poorly understood. The aim of this study is to provide a better …
Intestinal Ultrasound and Its Advanced Modalities in Characterizing Strictures in Crohn's Disease
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 40516640
BACKGROUND AND AIMS: Crohn's disease (CD) strictures exhibit varying levels of inflammation and chronicity. We evaluate whether intestinal ultrasound (IUS) is accurate in characterizing stricture composition. METHODS: This prospective, cross-sectional study included CD patients who underwent (IUS) prior to a small bowel segment resection. Histology in the resection specimen was …
IBD impact on quality of life and perception of disease activity in Italian patients and physicians: An IBD-PODCAST study sub analysis
Publication Year: 2025 Source: Dig Liver Dis PMID: 40517107 DOI: 10.1016/j.dld.2025.05.006
BACKGROUND: IBD-PODCAST was a global real-world study to assess suboptimal disease control (SDC) in patients with Crohn's disease (CD) and ulcerative colitis (UC) using STRIDE-II criteria. AIM: To evaluate quality of life (QoL), disease characteristics and control in patients with SDC, comparing perspectives of patients and healthcare providers (HCPs) in …
Coptis chinensis-derived extracellular vesicle-like nanoparticles delivered miRNA-5106 suppresses NETs by restoring zinc homeostasis to alleviate colitis
Publication Year: 2025 Source: J Nanobiotechnology PMID: 40517238 DOI: 10.1186/s12951-025-03466-z
BACKGROUND: Inflammatory bowel disease (IBD) is a chronic disorder marked by persistent inflammation and damage to the intestinal mucosa. Despite significant advances in treatment, there remains an unmet need for more effective and safer therapeutic strategies. RESULTS: In this study, we isolated and characterized extracellular vesicle-like nanoparticles (ELNs) derived from …
Microbial-Purine Metabolic Crosstalk Regulates Colitis-Related Intestinal Fibrosis: A Multi-Omics and Cohort Analysis Approach
Publication Year: 2025 Source: J Nutr Biochem PMID: 40517909 DOI: 10.1016/j.jnutbio.2025.109984
INTRODUCTION: Intestinal fibrosis (IF) is a severe complication of inflammatory bowel disease (IBD), often requiring surgical interventions. The modulating role of the microbial-metabolic link in IF remains unclear. We aimed to identify disturbances in microbiome-metabolome interactions during IF progression and recognize potential metabolic biomarkers. METHODS: Compositional and functional signatures, along …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide