Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Psychomotor development in infants following maternal exposure to biologics: Results from the DUMBO registry
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 40518059 DOI: 10.1016/j.cgh.2025.05.012
BACKGROUND AND AIMS: The impact of biologic treatment for inflammatory bowel disease (IBD) during pregnancy and lactation on infant psychomotor development is barely studied. We investigated the effect of exposure to biologics in utero or during breastfeeding on the psychomotor development of offspring during their first year METHODS: The study …
Perianal Disease in Pediatric-onset Crohn's Disease: Incidence, Disease Course, and Long-term Outcomes
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 40518062
BACKGROUND & AIMS: Perianal Crohn's disease (CD) is characterized by fistulae and/or abscesses in the anal region and leads to significant morbidity. We aimed to estimate the incidence and describe the disease course of perianal disease in pediatric-onset CD. METHODS: In a nationwide registry-based study, we included patients diagnosed with …
[Clinical practice guidelines for the management of therapeutic drug monitoring in pediatric inflammatory bowel disease (2025)]
Publication Year: 2025 Source: Zhonghua Er Ke Za Zhi PMID: 40518149
No Abstract
[Characteristics and clinical significance of neutrophil extracellular traps in children with inflammatory bowel disease]
Publication Year: 2025 Source: Zhonghua Er Ke Za Zhi PMID: 40518155 DOI: 10.3760/cma.j.cn112140-20241217-00922
Objective: To evaluate the characteristics of neutrophil extracellular traps (NET) in children with inflammatory bowel disease (IBD) and its role in diagnosis and disease activity monitoring. Methods: A total of 66 IBD children admitted to Beijing Children's Hospital from December 2017 to August 2024 were enrolled in this cross-sectional study, …
Patterns of Use and Discontinuation for Tumour Necrosis Factor Inhibitors in Pregnant Women: Insights from a Real-World Sample
Publication Year: 2025 Source: J Rheumatol PMID: 40518177 DOI: 10.3899/jrheum.2025-0048
OBJECTIVE: To evaluate tumour necrosis factor inhibitor (TNFi) usage patterns in pregnant women with rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), psoriasis (PsO), and inflammatory bowel diseases (IBD), and to compare corticosteroid use in those discontinuing TNFi at specific gestational time points versus those continuing throughout gestation. METHODS: …
Outcomes of Fecal Diversion in Perianal Crohn's Disease: A Systematic Review and Meta-Analysis
Publication Year: 2025 Source: J Dig Dis PMID: 40518593
OBJECTIVES: Perianal fistulizing Crohn's disease (pfCD) is a severe type of inflammatory bowel disease resulting in significant patient morbidity. Despite advancements in treatments, pfCD remains challenging to manage with low healing rates. Fecal diversion (FD) has previously demonstrated clinical improvement for patients with refractory disease. Our meta-analysis aimed to explore …
Macrophage barrier responses to oncogenic transformation
Publication Year: 2025 Source: Curr Opin Immunol PMID: 40518619
No Abstract
VirulentHunter: deep learning-based virulence factor predictor illuminates pathogenicity in diverse microbial contexts
Publication Year: 2025 Source: Brief Bioinform PMID: 40518950
Virulence factors (VFs) are critical determinants of bacterial pathogenicity, but current homology-based identification methods often miss novel or divergent VFs, and many machine learning approaches neglect functional classification. Here, we present VirulentHunter, a novel deep learning framework that enable simultaneous VF identification and classification directly from protein sequences by leveraging …
Diagnostic Value of Inflammatory Markers in Inflammatory Bowel Disease: Clinical and Endoscopic Correlations
Publication Year: 2025 Source: Cureus PMID: 40519394 DOI: 10.7759/cureus.84073
Background The incidence of inflammatory bowel diseases (IBD) has increased over the last century. Despite the unclear etiology of IBD, significant advancements have been made in recent years to understand the development of this disease. Objectives The aim of this study was to examine the diagnostic significance of several inflammatory …
The Unforeseen Connection: A Rare Case of Salpingo-Sigmoidal Fistula Secondary to Ulcerative Colitis
Publication Year: 2025 Source: Cureus PMID: 40519401
Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease characterized by continuous mucosal inflammation confined to the colon and rectum. Although fistulizing complications are a hallmark of Crohn's disease, they are exceedingly rare in UC, which typically involves only the mucosal layer. In these rare instances, however, prolonged and …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide