Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Patient Preferences for Treatment Attributes in Inflammatory Bowel Disease: A Discrete Choice Experiment Among Patients in Five Non-Western Countries
Publication Year: 2025 Source: Adv Ther PMID: 40526254 DOI: 10.1007/s12325-025-03249-w
INTRODUCTION: Understanding patient preferences is important for facilitating informed decision-making in managing patients with inflammatory bowel disease (IBD). This study explored the preferences of patients with Crohn's disease (CD) and ulcerative colitis (UC) regarding advanced therapy treatment attributes in five non-Western countries: Argentina, Australia, Brazil, Saudi Arabia and Taiwan. METHODS: …
Radiation Therapy for Abdominal or Pelvic Cancer Treatment in Patients with Inflammatory Bowel Disease: A Systematic Review
Publication Year: 2025 Source: Dig Dis Sci PMID: 40526318 DOI: 10.1007/s10620-025-09128-2
BACKGROUND: IBD is considered a relative contraindication to the use of radiation therapy (RT) due to risks of disease exacerbation and GI toxicity. Currently, there are limited available data on how well patients with IBD tolerate RT. METHODS: An electronic search was conducted on PubMed, Cochrane, Embase, and Medline. Eligible …
Treatment Options for the Comorbidity of Multiple Sclerosis With Other Chronic Inflammatory Diseases
Publication Year: 2025 Source: Dtsch Arztebl Int PMID: 40526577 DOI: 10.3238/arztebl.m2025.0088
BACKGROUND: Approximately 280 000 people in Germany suffer from multiple sclerosis (MS), an autoimmune disease of the central nervous system. Of these, approximately 5% have a comorbid chronic inflammatory disease: the more common ones are psoriasis, rheumatoid arthritis (RA), and chronic inflammatory bowel diseases (IBDs, of which the main types …
Gut Microbial Signatures Associated With Clinical Remission in Inflammatory Bowel Disease Treated With Biologics: A Comprehensive Multi-Cohort Analysis
Publication Year: 2025 Source: United European Gastroenterol J PMID: 40526755 DOI: 10.1002/ueg2.70064
BACKGROUND AND AIMS: The relationship between gut microbiota and biological treatment response in inflammatory bowel disease (IBD) remains incompletely understood. We sought to characterize microbial signatures associated with clinical remission and develop a prediction model for clinical remission. METHODS: We analyzed 16 S rRNA gene sequencing data from two independent …
[Proctitis: A Clinical Case of Unusual Etiology]
Publication Year: 2025 Source: Rev Med Chil PMID: 40526865
Proctitis frequently appears in inflammatory bowel diseases, mainly in ulcerative colitis. On the other hand, an increased incidence of sexually transmitted infections (STIs) has been described, which can start as proctitis. Additionally, the infectious etiology includes fecal-oral transmission pathogens as proctitis triggers. Similarly, non-infectious causes also play a role in …
IGF2BP2 regulates inflammation in ulcerative colitis through N6-methyladenosine-dependent modulation of CBR1
Publication Year: 2025 Source: Int Immunopharmacol PMID: 40526983
Ulcerative colitis (UC) is a chronic inflammatory disease characterized by damage to the colonic mucosa. N6-methyladenosine (m6A), an epigenetic modification of RNA, is involved in the pathogenesis of various human diseases. However, the function of m6A reader insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) in UC remains elusive. Herein, …
ILC3s sense gut microbiota through STING to initiate immune tolerance
Publication Year: 2025 Source: Immunity PMID: 40527323 DOI: 10.1016/j.immuni.2025.05.016
Immune tolerance to gut microbiota is necessary for health, yet the mechanisms initiating it remain elusive. We profiled MHC II(+) cells at single-cell resolution from the large intestine. Following colonization with the pathobiont Helicobacter hepaticus, group 3 innate lymphoid cells (ILC3s) were a key RORgammat(+) antigen-presenting cell that expressed low …
Clinical features, pathogenesis, and treatment of inflammatory bowel disease-associated spondyloarthritis
Publication Year: 2025 Source: Autoimmun Rev PMID: 40527403 DOI: 10.1016/j.autrev.2025.103853
Inflammatory bowel disease-associated spondyloarthritis (IBD-SpA) is a unique subtype of SpA that affects approximately 10-20 % of patients with IBD. It encompasses both peripheral arthritis and axial involvement, with enthesitis being increasingly recognized. Despite its clinical significance, there are currently no established screening tools, classification criteria, or standardized treatment guidelines …
The Ever-Evolving Relationship of Living With Inflammatory Bowel Disease
Publication Year: 2025 Source: Pediatrics PMID: 40527515
No Abstract
Correlations between genetically predicted iron-supplement drug targets and inflammatory bowel disease: A Mendelian randomization study
Publication Year: 2025 Source: Medicine (Baltimore) PMID: 40527798 DOI: 10.1097/MD.0000000000042729
This study investigates the causal relationship between genetically proxied iron-supplement drugs and inflammatory bowel disease (IBD) risk. After identifying 8 commonly used iron supplementation drugs based on the guidelines, a search for each of these drugs yielded 18 key regulatory targets and the locus information of each drug-targeted gene was …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide