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[Mechanism of total flavone of Abelmoschus manihot in treating ulcerative colitis and depression via intestinal flora-glycerophospholipid metabolism- macrophage polarization pathway]
Publication Year: 2025 Source: Zhongguo Zhong Yao Za Zhi PMID: 40350912
This study delves into the mechanism of total flavone of Abelmoschus manihot(TFA) in treating ulcerative colitis(UC) and depression via inhibiting M1 polarization of macrophages and reshaping intestinal flora and glycerolphospholipid metabolism. The study established a mouse model of UC and depression induced by chronic restraint stress(CRS) and dextran sulfate sodium(DSS). …
Cost per remission for mirikizumab versus ustekinumab for moderately to severely active ulcerative colitis treatment from the United States commercial payer perspective
Publication Year: 2025 Source: J Med Econ PMID: 40351121
INTRODUCTION: Mirikizumab, approved for the treatment of moderately to severely active ulcerative colitis (UC), may be prescribed in a similar placement to ustekinumab in second-line settings. Payers may compare the economic value when making formulary decisions. This study estimated and compared the cost per remission of the second-line therapies mirikizumab …
Infliximab-Induced Pulmonary Sarcoidosis Treated With Upadacitinib: A Case Report and Review of the Literature
Publication Year: 2025 Source: Cureus PMID: 40351964
No Abstract
Enteroenteric Fistula: A Rare Sequela of Unwitnessed Magnet Ingestion in a Child
Publication Year: 2025 Source: Cureus PMID: 40351972
Enteroenteric fistula is an abnormal connection between two loops of bowel, commonly caused by chronic inflammatory disease, malignancy, history of a surgical procedure, radiation, or foreign body ingestion. A previously healthy three-year-old female presented to the Emergency Department in Al Jalila Children's Specialty Hospital, Dubai, UAE, with a one-day history …
Retraction Note: Cirsimaritin Alleviates Dextran Sodium Sulfate-Induced Acute Colitis in Experimental Animals: A Therapeutic Approach for Inflammatory Bowel Disease
Publication Year: 2025 Source: Prev Nutr Food Sci PMID: 40352297
[This retracts the article on p. 31 in vol. 29, PMID: 38576881.].
Impact of fatigue in Crohn's disease is negatively related to resting state functional connectivity between the superior parietal lobule and parahippocampal gyrus/hippocampus
Publication Year: 2025 Source: Front Hum Neurosci PMID: 40352435 DOI: 10.3389/fnhum.2025.1561421
INTRODUCTION: Crohn's disease is one phenotype of inflammatory bowel disease (IBD). Fatigue is a common and burdensome symptom for persons with Crohn's disease. Despite its detrimental impact on health-related quality of life, the pathophysiology of fatigue in Crohn's disease is not fully understood. Specifically, basic research on the difference in …
Exploring ANCA Pathogenicity in Ulcerative Colitis: A Case Report Highlighting the Risk of Progression to ANCA-Associated Vasculitis
Publication Year: 2025 Source: Eur J Case Rep Intern Med PMID: 40352707
No Abstract
Aryl Hydrocarbon Receptor (AHR) is required for repopulation of decellularized intestinal colon scaffolds
Publication Year: 2025 Source: MicroPubl Biol PMID: 40353141
This study investigates the role of the ligand-activated transcription factor AHR in repopulating the intestinal lining. Using organoid-derived cells and decellularized mouse intestinal scaffolds to investigate the importance of AHR in regulating intestinal regeneration, we found that silencing AHR expression hinders the capacity of colonic cells to repopulate decellularized colons. …
Unraveling the Nutritional Perspectives of Probiotics and Prebiotics in Female Healthcare
Publication Year: 2025 Source: Recent Adv Food Nutr Agric PMID: 40353421 DOI: 10.2174/012772574X374047250325183211
Prebiotics are the indigestible components of meals that promote the formation of probiotics, that contain living bacteria that have positive effects. Synbiotics combine the two. These components may be found in foods such as fresh fruits and vegetables, fermented foods like yogurt and pickles, or pharmaceutical preparations and functional meals …
Correction: Development of a novel complex inflammatory bowel disease mouse model: Reproducing human inflammatory bowel disease etiologies in mice
Publication Year: 2025 Source: PLoS One PMID: 40354309
[This corrects the article DOI: 10.1371/journal.pone.0311310.].
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