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Special Considerations in Pediatric Inflammatory Bowel Disease Pathology
Publication Year: 2025 Source: Diagnostics (Basel) PMID: 40218181 DOI: 10.3390/diagnostics15070831
Inflammatory bowel disease (IBD) in the pediatric population presents distinct characteristics compared to adult cases. Pathology plays a critical role in its diagnosis, and this review underscores key considerations in the pathologic evaluation of pediatric IBD. Recognizing inflammatory patterns in the upper gastrointestinal tract can improve disease classification and aid …
Inflammatory Pseudotumor of the Anal Canal Mimicking Colorectal Cancer: Case Report and Hints to Improve a Patient's Fitness for Treatment and Prevention
Publication Year: 2025 Source: Diagnostics (Basel) PMID: 40218238
Background and Clinical Significance: Men who engage in anal fisting may experience full rectal and colon thickness injury resulting in an endoscopic emergency. The endoscopist does not routinely question patients about their sexual habits, nor are patients compliant with counseling during the endoscopy procedure as indicated by the infectious disease …
Artificial Intelligence in Inflammatory Bowel Disease Endoscopy
Publication Year: 2025 Source: Diagnostics (Basel) PMID: 40218255 DOI: 10.3390/diagnostics15070905
Inflammatory bowel diseases (IBDs), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic immune-mediated inflammatory diseases of the gastrointestinal (GI) tract with still-elusive etiopathogeneses and an increasing prevalence worldwide. Despite the growing availability of more advanced therapies in the last two decades, there are still a number of unmet …
Sex Differences Outweigh Dietary Factors in Food-Related Quality of Life in Patients with Inflammatory Bowel Disease
Publication Year: 2025 Source: Nutrients PMID: 40218872 DOI: 10.3390/nu17071114
BACKGROUND: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), consists of chronic gastrointestinal inflammation, with nutrition playing a significant role in its development. IBD patients often face dietary challenges affecting their quality of life (QoL), yet research on food-related QoL (FR-QoL) and sex-specific differences is limited. …
Nutraceuticals in the Management of Intestinal Inflammation-Current Advances and Future Challenges
Publication Year: 2025 Source: Nutrients PMID: 40218928
Gut immunity begins developing in the early years in humans and is crucial in the maintenance of gut health in adult life [...].
Targeting Bile-Acid Metabolism: Nutritional and Microbial Approaches to Alleviate Ulcerative Colitis
Publication Year: 2025 Source: Nutrients PMID: 40218932
Ulcerative colitis (UC) is a chronic inflammatory disease affecting the colorectum, posing a significant global health burden. Recent studies highlight the critical role of gut microbiota and its metabolites, particularly bile acids (BAs), in UC's pathogenesis. The relationship between BAs and gut microbiota is bidirectional: microbiota influence BA composition, while …
Beneficial Effects of Omega-3 Fatty Acids on Obesity and Related Metabolic and Chronic Inflammatory Diseases
Publication Year: 2025 Source: Nutrients PMID: 40219010
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are known to help resolve inflammation through generation of anti-inflammatory eicosanoids and specialized pro-resolving mediators, including resolvins, protectins, and maresins. Through binding to the GPR120/FFAR4 receptor, their beneficial effects result from phospholipid membrane remodeling, impairment of inflammatory signaling molecules clustering, subsequent inhibition of NF-kappaB …
[Classical Sweet syndrome with multiple organ lesions by (18)F-FDG PET/CT: A case report]
Publication Year: 2025 Source: Beijing Da Xue Xue Bao Yi Xue Ban PMID: 40219578
Sweet syndrome (acute febrile neutrophilic dermatosis) is a relatively rare inflammatory di-sease, which is characterized by the sudden appearance of tender erythematous skin lesions, often accompanied by pyrexia and elevated neutrophil count. The pathogenesis is not clear yet. Recently, multiple studies have found the association between Sweet syndrome and infections, …
RCPE in association with the American College of Gastroenterology and the Scottish Society of Gastroenterology - Gastroenterology: A global perspective
Publication Year: 2025 Source: J R Coll Physicians Edinb PMID: 40219669 DOI: 10.1177/14782715251332318
On 6 November 2024, the Royal College of Physicians of Edinburgh (RCPE) hosted its annual gastroenterology symposium, marking the first collaboration with the American College of Gastroenterology (ACG) and the Scottish Society of Gastroenterology (SSG). The event addressed key global challenges in gastroenterology, including obesity, liver disease, inflammatory bowel disease …
The role of bacteriophage in inflammatory bowel disease and its therapeutic potential
Publication Year: 2025 Source: Crit Rev Microbiol PMID: 40219702 DOI: 10.1080/1040841X.2025.2492154
Inflammatory bowel disease (IBD) refers to a group of chronic inflammatory disorders impacting the gastrointestinal (GI) tract. It represents a significant public health challenge due to its rising global incidence and substantial impact on patients' quality of life. Emerging research suggests a pivotal role of the human microbiome in IBD …
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