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Fruit-Based Diet and Gut Health: A Review
Publication Year: 2025 Source: Food Sci Nutr PMID: 40313793 DOI: 10.1002/fsn3.70159
Gut health is essential to the overall well-being of a human being due to its implication on digestion, the performance of the immune system, and nutritional absorption. The gut microbiota represents an intricate ecology of bacteria, fungi, and viruses, important in regulating the immune response and maintaining intestinal health. Fruit-based …
Crohn's Colitis Care, a Disease-Specific Electronic Medical Record, Enhances Data Capture in Pediatric Inflammatory Bowel Disease Care
Publication Year: 2025 Source: JGH Open PMID: 40314025
BACKGROUND AND AIM: Crohn's Colitis Care, a structured, disease-specific electronic medical record, is proven to promote more complete data capture in adult Inflammatory Bowel Disease care. This study aimed to determine whether similar effectiveness was seen in pediatrics. METHODS: Matched patient records from a hospital's standard electronic medical record (pre-Crohn's …
Mapping conditional health literacy and digital health literacy in patients with inflammatory bowel disease to optimise availability of digital health information: a cross-sectional study
Publication Year: 2025 Source: Scand J Gastroenterol PMID: 40314186 DOI: 10.1080/00365521.2025.2497952
BACKGROUND AND AIMS: Health literacy and digital health literacy are crucial for spreading information that enhances self-management and health outcomes. IBD patients have called for relevant and reliable information to enable self-management. However, mapping conditional capacities for adapting IBD health information remains unaddressed. This study examines IBD patients' health literacy …
Knowledge Mapping of International Microbiota Research: Analyzing Thirty-Year Citation Classics and Exploring Future Expectations
Publication Year: 2025 Source: New Microbiol PMID: 40314681
Microbiota research has rapidly emerged as a pivotal field, with over 250,000 publications and more than ten million citations recorded in the Web of Science Core Collection database by 2024. There were 1682 original microbiota citation classics (each receiving 400 citations or more) identified over the past three decades, totaling …
Immunopathological and microbial signatures of inflammatory bowel disease in partial RAG deficiency
Publication Year: 2025 Source: J Exp Med PMID: 40314722 DOI: 10.1084/jem.20241993
Partial RAG deficiency (pRD) can manifest with systemic and tissue-specific immune dysregulation, with inflammatory bowel disease (IBD) in 15% of the patients. We aimed at identifying the immunopathological and microbial signatures associated with IBD in patients with pRD and in a mouse model of pRD (Rag1w/w) with spontaneous development of …
Impact of early aggressive treatment on long-term biochemical marker patterns in inflammatory bowel disease
Publication Year: 2025 Source: J Gastroenterol PMID: 40314771 DOI: 10.1007/s00535-025-02244-w
BACKGROUNDS: The disease course of inflammatory bowel disease (IBD) is highly variable; early and precise identification of patients with poor outcomes is crucial. We aimed to classify the long-term disease course of IBD using biochemical markers and evaluate the clinical factors associated with different disease courses. METHODS: A latent class …
Comments on "Evaluation of an Exercise Program in Patients with Inflammatory Bowel Disease: A Pilot Study"
Publication Year: 2025 Source: Dig Dis Sci PMID: 40314910
No Abstract
HLA DQA1*05 and Risk of Antitumor Necrosis Factor Treatment Failure and Anti-Drug Antibody Development in Children With Crohn's Disease
Publication Year: 2025 Source: Am J Gastroenterol PMID: 40315028
No Abstract
Epigenetic mechanism of iPSC-MSC-EVs in colonic epithelial cell pyroptosis in ulcerative colitis cell models via modulation of ELF3/miR-342-3p/KDM6B axis and histone methylation
Publication Year: 2025 Source: Int Immunopharmacol PMID: 40315630
Ulcerative colitis (UC) is a chronic inflammatory bowel disease in the colon and rectum. Mesenchymal stem cell-derived extracellular vesicles (MSCs-EVs) have emerged as promising cell-free therapeutics for UC, leveraging their immunomodulatory and tissue-protective properties. However, the specific epigenetic mechanisms by which EVs regulate pyroptosis (an inflammatory cell death pathway) remain …
Crataegus pinnatifida polysaccharide alleviates DSS-induced colitis in mice by regulating the intestinal microbiota and enhancing arginine biosynthesis
Publication Year: 2025 Source: Phytomedicine PMID: 40315641
BACKGROUND: The development of effective and safe dietary supplements is essential for both the prevention and management of ulcerative colitis (UC), as its pathogenesis is intricate and difficult to completely resolve. Crataegus pinnatifida, a medicinal food with a long history of use, has broad medicinal value. Recent research has revealed …
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