Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Potential therapeutic strategies targeting efferocytosis for inflammation resolution and tissue repair in inflammatory bowel disease
Publication Year: 2025 Source: Cell Immunol PMID: 40315792 DOI: 10.1016/j.cellimm.2025.104957
Efferocytosis, the process by which apoptotic cells (ACs) are recognized and cleared by phagocytes, is a critical mechanism in maintaining intestinal immune homeostasis and promoting the resolution of inflammation. Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), is characterized by chronic intestinal inflammation, wherein defective efferocytosis …
Isolated perianal Crohn's disease: a systematic review and expert consensus proposing novel diagnostic criteria and management advice
Publication Year: 2025 Source: Lancet Gastroenterol Hepatol PMID: 40315877 DOI: 10.1016/S2468-1253(25)00007-X
Perianal fistulae can present a diagnostic challenge when distinguishing perianal Crohn's disease from idiopathic perianal fistulae. This distinction is key, as perianal Crohn's disease requires inflammatory bowel disease (IBD) therapy, whereas idiopathic perianal fistulae are primarily managed surgically. When luminal inflammation is absent, but Crohn's disease is suspected, the term …
Investigating sarcopenia in pediatric Crohn's Disease with magnetic resonance enterography: An observational study
Publication Year: 2025 Source: Clin Nutr ESPEN PMID: 40315990 DOI: 10.1016/j.clnesp.2025.04.027
BACKGROUND AND AIMS: Sarcopenia has a negative impact on clinical outcome in adult patients with Crohn's Disease (CD), but data on children are scarce. The aim of this study is to evaluate the prevalence of sarcopenia in children with CD using magnetic resonance enterography (MRE) and describe its relationship with …
Anti-colitis comparison of polysaccharides and anthocyanins extracted from black wolfberry based on microbiomics, immunofluorescence and multi-cytokines profile analysis
Publication Year: 2025 Source: Int J Biol Macromol PMID: 40316082
Black wolfberry (Lycium ruthenicum) is a widely consumed food known for its pharmacological properties, particularly its anti-inflammatory and antioxidant effects. This study investigates the therapeutic potential of black wolfberry polysaccharides (LRP) and anthocyanins (LRA) in treating ulcerative colitis, a chronic inflammatory bowel disease. Using a DSS-induced mouse model of colitis, …
Role of artificial intelligence in early identification and risk evaluation of non-communicable diseases: a bibliometric analysis of global research trends
Publication Year: 2025 Source: BMJ Open PMID: 40316361
OBJECTIVE: This study aims to shed light on the transformative potential of artificial intelligence (AI) in the early detection and risk assessment of non-communicable diseases (NCDs). STUDY DESIGN: Bibliometric analysis. SETTING: Articles related to AI in early identification and risk evaluation of NCDs from 2000 to 2024 were retrieved from …
Impact of Amerindian ancestry on clinical outcomes in Crohn's disease and ulcerative colitis in a Latino population
Publication Year: 2025 Source: Sci Rep PMID: 40316706 DOI: 10.1038/s41598-025-99543-2
Research in Inflammatory Bowel Disease (IBD) assessing the genetic structure and its association with IBD phenotypes is needed, especially in IBD-underrepresented populations such as the South American IBD population. Aim. We examine the correlation between Amerindian ancestry and IBD phenotypes within a South American cohort and investigate the association between …
Peristaltic contractility: another factor impacting IPAA function?
Publication Year: 2025 Source: Int J Colorectal Dis PMID: 40316843
PURPOSE: This study aims to investigate the phenomenon of high-amplitude pouch contractile waves and their impact on functional results in patients undergoing ileal pouch-anal anastomosis following total proctocolectomy for ulcerative colitis. METHODS: This is an observational cohort study evaluating pouch manometric data at an early (study 1, < 6 months …
Identifying and Managing Fraudulent Respondents in Online Stated Preferences Surveys: A Case Example from Best-Worst Scaling in Health Preferences Research
Publication Year: 2025 Source: Patient PMID: 40316881 DOI: 10.1007/s40271-025-00740-y
BACKGROUND: There is limited evidence and guidance in health preferences research to prevent, identify, and manage fraudulent respondents and data fraud, especially for best-worst scaling (BWS) and discrete choice experiments with nonordered attributes. Using an example from a BWS survey in which we experienced data fraud, we aimed to: (1) …
Sacral neuromodulation improves functional outcome and quality of life in patients with pouch dysfunction after pan proctocolectomy for ulcerative colitis
Publication Year: 2025 Source: Tech Coloproctol PMID: 40317418
BACKGROUND: Postoperative frequency of bowel movements and impaired fecal continence (FI) has a negative impact on quality of life following ileal pouch-anal anastomosis. Sacral neuromodulation (SNM) is a validated treatment of FI, but its effectiveness in patients with ileal pouch-anal anastomosis (IPAA) has been poorly reported. The aim was to …
Chronic Lipopolysaccharide Exposure Causes AD-Like Pathology in Male Mice With Intact Blood-Brain Barrier
Publication Year: 2025 Source: FASEB J PMID: 40317532 DOI: 10.1096/fj.202403117RR
Chronic inflammatory conditions like periodontitis and inflammatory bowel disease (IBD) are reported to contribute to the pathogenesis of late-onset Alzheimer's disease (AD). Gram-negative bacteria are the main bacterial species causing oral and gut mucosal infections. Lipopolysaccharide (LPS) is a major inflammation-inducing molecule in Gram-negative bacteria. LPS derived from the oral …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide