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Inflammatory Bowel Disease and Breastfeeding: A Narrative Review

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38439613 DOI: 10.1093/ibd/izae033

Inflammatory bowel disease (IBD) frequently affects women of childbearing age who may consider breastfeeding. Although breastfeeding has numerous benefits, there remain concerns regarding the safety of breastfeeding among women with IBD. Breastfeeding is important in developing the immune system of infants and has been shown to protect against the development …

Dietary Interventions and Supplementation in Patients With an Ileal Pouch-Anal Anastomosis: A Systematic Review

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38452029 DOI: 10.1093/ibd/izae037

No Abstract

The Time to Inflammatory Bowel Disease Diagnosis for Patients Presenting with Abdominal Symptoms in Primary Care and its Association with Emergency Hospital Admissions and Surgery: A Retrospective Cohort Study

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38563769 DOI: 10.1093/ibd/izae057

BACKGROUND: Patients with inflammatory bowel disease (IBD) presenting to primary care may experience diagnostic delays. We aimed to evaluate this and assess whether time to diagnosis is associated with clinical outcomes. METHODS: A retrospective cohort study using English primary care data from January 1, 2010, to December 31, 2019, linked …

Prior Appendectomy Is Associated With a Milder Clinical Course in Crohn's Disease: A Nationwide Population-based Cohort Study

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38564416

BACKGROUND: Appendectomy may affect the clinical course of Crohn's disease (CD), but rigorous evidence is sparse and contradicting. The aim of this study was to examine the association between appendectomy and the clinical course of CD. METHODS: All patients diagnosed with CD in Denmark in the period from 1977 to …

Increased Risk of Inflammatory Bowel Disease Among Patients With Nontyphoidal Salmonella Infections: A Population-Based Cohort Study

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38567440 DOI: 10.1093/ibd/izae053

BACKGROUND: Despite the known association between microorganisms and development of inflammatory bowel disease (IBD), the role of nontyphoidal Salmonella (NTS) in IBD is not adequately addressed. We aimed at elucidating the relationship between NTS infection and the risk of IBD. METHODS: Based on the National Health Insurance Research Database in …

Effectiveness and safety of adalimumab biosimilar in patients with inflammatory bowel disease

Publication Year: 2025 Source: Farm Hosp PMID: 38570210

No Abstract

Durability of the First Biologic in Children and Adults With Ulcerative Colitis: A Nationwide Study from the epi-IIRN

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38578929

BACKGROUND: In this nationwide study, our objective was to compare the durability of first-line biologics in ulcerative colitis (UC), categorized into monotherapy and combotherapy with immunomodulators. METHODS: We utilized data from the nationwide epi-IIRN cohort from 2005 to 2020. Durability was defined as consistent treatment without surgery. Comparisons were based …

NOD2 and Crohn's Disease Clinical Practice: From Epidemiology to Diagnosis and Therapy, Rewired

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38582044

Crohn's disease (CD) is a chronic inflammatory bowel disease with a multifactorial pathogenesis involving environmental and genetic factors. Since the late 20th century, the discovery of the first susceptibility gene (NOD2, previously referred to as CARD15) for CD has paved the way for further investigations into the correlations between clinical …

Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice

Publication Year: 2025 Source: J Adv Res PMID: 38582300 DOI: 10.1016/j.jare.2024.03.026

INTRODUCTION: Inflammatory bowel disease (IBD) is a global disease with limited therapy. It is reported that sedanolide exerts anti-oxidative and anti-inflammatory effects as a natural phthalide, but its effects on IBD remain unclear. OBJECTIVES: In this study, we investigated the impacts of sedanolide on dextran sodium sulfate (DSS)-induced colitis in …

Association between bowel movement frequency and erectile dysfunction in patients with ulcerative colitis: a cross-sectional study

Publication Year: 2025 Source: Int J Impot Res PMID: 38589515

No Abstract

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