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Determining the time to cholangiocarcinoma in pediatric-onset PSC-IBD
Publication Year: 2025 Source: J Pediatr Gastroenterol Nutr PMID: 39704261 DOI: 10.1002/jpn3.12443
Primary sclerosing cholangitis (PSC) is a risk factor for cholangiocarcinoma. When a child is diagnosed with both PSC and inflammatory bowel disease (IBD), evidence-based information on counseling families and risk management of developing cholangiocarcinoma is limited. In this case series (PubMed/collaborators), we included patients with PSC-IBD who developed cholangiocarcinoma and …
Evaluating the cost-utility of ferric derisomaltose versus ferric carboxymaltose in patients with inflammatory bowel disease and iron deficiency anaemia in Norway
Publication Year: 2025 Source: J Med Econ PMID: 39704663 DOI: 10.1080/13696998.2024.2444833
AIMS: Iron deficiency anemia (IDA) is among the most common extraintestinal sequelae of inflammatory bowel disease (IBD). Intravenous iron is often the preferred treatment in patients with active inflammation with or without active bleeding, iron malabsorption, or intolerance to oral iron. The aim of the present study was to evaluate …
[Imaging in chronic inflammatory bowel disease]
Publication Year: 2025 Source: Inn Med (Heidelb) PMID: 39704791 DOI: 10.1007/s00108-024-01831-y
In patients with chronic inflammatory bowel disease (IBD), endoscopic techniques (including capsule techniques and balloon enteroscopy for the small intestine), ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) are primarily used as often complementary imaging techniques. Radiation exposure needs to be kept in mind when using CT and …
Small Molecules, Big Results: How JAK Inhibitors Have Transformed the Treatment of Patients with IBD
Publication Year: 2025 Source: Dig Dis Sci PMID: 39704903 DOI: 10.1007/s10620-024-08792-0
Small molecule Janus kinase (JAK) inhibitors have revolutionized the management of ulcerative colitis (UC) and Crohn's disease (CD) through their low immunogenicity, safety, and consistent pharmacologic response that are superior to existing therapeutic options. In this perspective, we highlight existing evidence supporting the use of currently approved JAK inhibitors (upadacitinib, …
Predictive value of three nutritional indexes for disease activity in patients with inflammatory bowel disease
Publication Year: 2025 Source: Ann Med PMID: 39705015 DOI: 10.1080/07853890.2024.2443256
BACKGROUND: Malnutrition is prevalent in patients with inflammatory bowel disease (IBD); however, its ability to predict the disease activity in IBD remains unexplored. Therefore, this study aimed to explore the association between malnutrition and disease activity in IBD. METHODS: In this retrospective study, we enrolled 1006 patients diagnosed with IBD …
A Complicated Matter: Predictors for Postoperative Infections After Bowel Resection in Pediatric Inflammatory Bowel Disease
Publication Year: 2025 Source: J Pediatr Surg PMID: 39705781 DOI: 10.1016/j.jpedsurg.2024.162105
INTRODUCTION: Children with inflammatory bowel disease (IBD) need surgery whenever medical therapy fails. The postoperative course is frequently accompanied by symptoms suggestive of infection, such as fever. The aim of our study was to analyze the postoperative course after bowel resection in pediatric IBD patients in relation to postoperative infections. …
De novo interleukin-10 production primed by Lactobacillus sakei CVL-001 amplifies the immunomodulatory abilities of mesenchymal stem cells to alleviate colitis
Publication Year: 2025 Source: Biomed Pharmacother PMID: 39705909 DOI: 10.1016/j.biopha.2024.117745
Mesenchymal stem cells (MSCs) hold therapeutic promise for treating inflammatory bowel disease (IBD) owing to their immunomodulatory properties. Currently, pre-conditioning strategies with several beneficial agents have been applied to enhance the efficacy of MSCs in treating IBDs. Probiotics are increasingly acknowledged as supplemental therapy for IBD; however, their potential benefits …
Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies
Publication Year: 2025 Source: Lancet PMID: 39706209
No Abstract
Advancing Pediatric Robotic Colorectal Surgery: Trends, Outcomes, and Future Directions-A Comprehensive Review
Publication Year: 2025 Source: Eur J Pediatr Surg PMID: 39706224 DOI: 10.1055/a-2506-6590
INTRODUCTION: Pediatric robotic colorectal surgery has rapidly evolved, offering enhanced precision and safety for treating complex conditions such as Hirschsprung disease (HSCR), anorectal malformations (ARMs), and inflammatory bowel disease (IBD). This review analyzes recent trends, outcomes, and complications in robotic colorectal procedures for pediatric patients. MATERIALS AND METHODS: A systematic …
A case of Vibrio pelagius in a child with inflammatory bowel disease
Publication Year: 2025 Source: Indian J Med Microbiol PMID: 39706279
No Abstract
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