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Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Publication Year: 2025 Source: Biochim Biophys Acta Mol Basis Dis PMID: 39706352 DOI: 10.1016/j.bbadis.2024.167634

Psoriasis is a chronic skin disease occasionally associated with abdominal symptoms and IBD. We aimed to characterize intestinal immune cells and the integrity of the intestinal barrier in psoriasis. Biopsies from the duodenum and colon were analyzed by flow cytometry and immunohistochemistry for the presence and activation status of different …

Evaluation of the Effect of Risankizumab on the Pharmacokinetics of Cytochrome P450 Substrates in Patients with Moderately to Severely Active Ulcerative Colitis or Crohn's Disease

Publication Year: 2025 Source: Clin Pharmacokinet PMID: 39707077

No Abstract

Transauricular vagal nerve stimulation suppresses inflammatory responses in the gut and brain in an inflammatory bowel disease model

Publication Year: 2025 Source: J Anat PMID: 39707162 DOI: 10.1111/joa.14178

Inflammatory bowel disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis (UC), is a major health problem on a global scale and its treatment is unsatisfactory. We aimed to investigate the effects of transauricular vagal nerve stimulation (tVNS) on inflammation in rats with IBD induced by trinitrobenzene sulfonic acid (TNBS). …

Update on Autoimmune Pancreatitis and IgG4-Related Disease

Publication Year: 2025 Source: United European Gastroenterol J PMID: 39707927

No Abstract

Effectiveness and Treatment Persistence of Vedolizumab Compared to Anti-Tumour Necrosis Factor-α in Patients With Crohn's Disease: A Systematic Literature Review and Meta-Analysis

Publication Year: 2025 Source: United European Gastroenterol J PMID: 39707930

No Abstract

Escherichia coli Nissle Improves Short-Chain Fatty Acid Absorption and Barrier Function in a Mouse Model for Chronic Inflammatory Diarrhea

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39708301

BACKGROUND: Defects in SLC26A3, the major colonic Cl-/HCO3- exchanger, result in chloride-rich diarrhea, a reduction in short-chain fatty acid (SCFA)-producing bacteria, and a high incidence of inflammatory bowel disease in humans and in mice. Slc26a3-/- mice are, therefore, an interesting animal model for spontaneous but mild colonic inflammation and for …

Capilliposide A alleviates DSS-induced colitis by regulating the intestinal flora and its metabolites of origin

Publication Year: 2025 Source: Int Immunopharmacol PMID: 39708482

No Abstract

Plasma bile acid profile analysis by liquid chromatography-tandem mass spectrometry and its application in healthy subjects and IBD patients

Publication Year: 2025 Source: J Pharm Biomed Anal PMID: 39709683 DOI: 10.1016/j.jpba.2024.116639

Bile acids (BAs), not only promote the absorption of fat-soluble nutrients and regulate the metabolism of multiple substances but also have a potential role as diagnostic and prognostic indicators in a variety of diseases such as cholestasis, hepatocellular carcinoma, and diabetes mellitus. Here, a rapid and sensitive liquid chromatography-tandem mass …

Extraction of American ginseng polysaccharide by ultrasound-assisted deep eutectic solvents-based three-phase partitioning: Process optimization, structural characterization, and anti-ulcerative colitis study

Publication Year: 2025 Source: Ultrason Sonochem PMID: 39709739

No Abstract

Widening access to recombinant zoster vaccination in IBD

Publication Year: 2025 Source: Lancet Gastroenterol Hepatol PMID: 39709982 DOI: 10.1016/S2468-1253(24)00429-1

No Abstract

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