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Dual-action microparticles for ulcerative colitis: Cellulose nanofibers-enhanced delivery of 5-ASA and probiotics
Publication Year: 2025 Source: Int J Biol Macromol PMID: 39710030
No Abstract
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules
Publication Year: 2025 Source: J Control Release PMID: 39710207 DOI: 10.1016/j.jconrel.2024.12.041
Inflammatory bowel disease (IBD) is a chronic or recurrent inflammatory disorder affecting various parts of the gastrointestinal tract. Metformin, a widely prescribed hypoglycemic drug for type 2 diabetes, has shown potential in reducing IBD risk. However, its oral administration faces significant challenges due to the harsh gastrointestinal environment, requiring higher …
Analysis of "Inflammatory Markers at Birth and Risk of Early-Onset Inflammatory Bowel Disease"
Publication Year: 2025 Source: Gastroenterology PMID: 39710339
No Abstract
Comments on "Inflammatory Markers at Birth and Risk of Early-Onset Inflammatory Bowel Disease"
Publication Year: 2025 Source: Gastroenterology PMID: 39710340
No Abstract
Re-evaluating the Association Between Neonatal Inflammatory Markers and Early-Onset IBD Risk
Publication Year: 2025 Source: Gastroenterology PMID: 39710342 DOI: 10.1053/j.gastro.2024.11.027
No Abstract
Characteristics and outcomes of portal vein thrombosis in patients with inflammatory bowel disease in Korea
Publication Year: 2025 Source: Korean J Intern Med PMID: 39710845 DOI: 10.3904/kjim.2024.181
BACKGROUND/AIMS: Portal vein thrombosis (PVT) frequently occurs in patients with inflammatory bowel disease (IBD), particularly when influenced by factors such as abdominal infections, IBD flare-ups, or surgical procedures. The implications of PVT range from immediate issues such as intestinal ischemia to long-term concerns including portal hypertension and its complications. However, …
Bone-Marrow-Targeted Nanocomposite Abrogates C-Myb-Survivin Cross Talk in MLL-AF9-Rearranged Acute Myeloid Leukemia in In Vitro and In Vivo Patient-Derived Xenograft Models
Publication Year: 2025 Source: ACS Appl Mater Interfaces PMID: 39711012 DOI: 10.1021/acsami.4c18737
The heterogeneous form of malignancy in the myeloid lineage of normal hematopoietic stem cells (HSCs) is characterized as acute myeloid leukemia (AML). The t(9;11) reciprocal translocation (p22;q23) generates MLL-AF9 oncogene, which results in myeloid-based monoblastic AML with frequent relapse and poor survival. MLL-AF9 binds with the C-Myb promoter and regulates …
Deep Learning-Enabled Rapid Metabolic Decoding of Small Extracellular Vesicles via Dual-Use Mass Spectroscopy Chip Array
Publication Year: 2025 Source: Anal Chem PMID: 39711466
No Abstract
Detection of antibodies to infliximab in routine care: a 4-year French retrospective study
Publication Year: 2025 Source: Clin Exp Immunol PMID: 39714327
Despite its wide use to treat various inflammatory diseases, infliximab becomes ineffective in some patients due to inadequate drug levels and production of anti-drug antibodies (ADA). The aim of this study was to compare the prevalence and ADA levels in a large cohort of patients. ADA and infliximab (IFX) through …
[New treatment targets for inflammatory bowel disease?]
Publication Year: 2025 Source: Inn Med (Heidelb) PMID: 39714486 DOI: 10.1007/s00108-024-01826-9
The classic therapeutic goals of chronic inflammatory bowel disease (IBD) are, on the one hand, clinical remission and, on the other, the prevention of disease progression. The introduction of additional "targets" such as normalization of laboratory inflammation values, endoscopic and, possibly, histological mucosal healing and transmural parameters (ultrasound, magnetic resonance …
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