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Primary sclerosing cholangitis in children with inflammatory bowel disease: An ESPGHAN position paper from the Hepatology Committee and the IBD Porto group
Publication Year: 2025 Source: J Pediatr Gastroenterol Nutr PMID: 39741383 DOI: 10.1002/jpn3.12378
OBJECTIVE: We aimed to provide an evidence-supported approach to diagnose, monitor, and treat children with inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC). METHODS: The core group formulated seven PICO-structured clinical questions. A systematic literature search from inception to December 2022 was conducted by a medical librarian using MEDLINE …
Endoluminal approaches for colorectal neoplasia in inflammatory bowel disease: a viable alternative for colectomy?
Publication Year: 2025 Source: J Gastrointest Surg PMID: 39521036 DOI: 10.1016/j.gassur.2024.101876
BACKGROUND: Endoscopic resection of visible dysplastic lesions in patients with inflammatory bowel disease (IBD) is an alternative to colectomy. The endoscopic techniques that can be used include endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), and ESD combined with EMR. These endoscopic approaches may allow organ preservation in patients with …
Nationwide multicenter prospective study on the usefulness, safety, and acceptability of colon capsule endoscopy in Japan
Publication Year: 2025 Source: Gastrointest Endosc PMID: 39521091
No Abstract
Pro-inflammatory NK-like T cells are expanded in the blood and inflamed intestine in Crohn's disease
Publication Year: 2025 Source: Mucosal Immunol PMID: 39521274
No Abstract
Creeping Fat-Derived Free Fatty Acids Induce Hyperplasia of Intestinal Muscularis Propria Muscle Cells: A Novel Link Between Fat and Intestinal Stricture Formation in Crohn's Disease
Publication Year: 2025 Source: Gastroenterology PMID: 39522890
No Abstract
Ulcerative Colitis in Pregnancy: A Japanese Multicenter Cohort Study Focusing on Their Mutual Influence
Publication Year: 2025 Source: Intern Med PMID: 39522998
No Abstract
Revolutionizing IBD research with on-chip models of disease modeling and drug screening
Publication Year: 2025 Source: Trends Biotechnol PMID: 39523166 DOI: 10.1016/j.tibtech.2024.10.002
Inflammatory bowel disease (IBD) comprises chronic inflammatory conditions with complex mechanisms and diverse manifestations, posing significant clinical challenges. Traditional animal models and ethical concerns in human studies necessitate innovative approaches. This review provides an overview of human intestinal architecture in health and inflammation, emphasizing the role of microfluidics and on-chip …
Antibiotic usage within the first year of life has a protective effect against ulcerative colitis in South Korea: A nationwide cohort study
Publication Year: 2025 Source: Dig Liver Dis PMID: 39523197
No Abstract
Determination of optimal cutoff value of ulcerative colitis intestinal ultrasound index to estimate endoscopic improvement in ulcerative colitis
Publication Year: 2025 Source: J Gastroenterol PMID: 39523231
No Abstract
Gut fungal profile in new onset treatment-naïve ulcerative colitis in Saudi children
Publication Year: 2025 Source: Saudi J Gastroenterol PMID: 39523762 DOI: 10.4103/sjg.sjg_221_24
BACKGROUND: Although the role of fungi in gut inflammation in IBD has been suggested, data are still limited in ulcerative colitis (UC). Our aim was to describe the gut fungal profile in a pediatric UC in Saudi Arabia. METHODS: Fecal samples from children with UC and control samples provided by …
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