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Vascular endothelial growth factor in inflammatory bowel disease: A systematic review and meta-analysis

Publication Year: 2025 Source: Eur J Clin Invest PMID: 39545600 DOI: 10.1111/eci.14361

AIM: Vascular endothelial growth factor (VEGF) is linked to inflammation and angiogenesis, indicating a possible role in inflammatory bowel disease (IBD) and its main clinical manifestations, Crohn's disease (CD) and ulcerative colitis (UC). This systematic review and meta-analysis investigated studies assessing circulating VEGF concentrations in IBD patients and healthy controls, …

Short Term Biologicals in Pediatric IBD

Publication Year: 2025 Source: Indian J Pediatr PMID: 39546121 DOI: 10.1007/s12098-024-05323-7

No Abstract

Neohesperidin protects against colitis-associated colorectal cancer in mice via suppression of the NF-κB/p65 and MAPK pathways

Publication Year: 2025 Source: J Nutr Biochem PMID: 39547268 DOI: 10.1016/j.jnutbio.2024.109804

Patients with inflammatory bowel disease (IBD) are at increased risk of developing colitis-associated colorectal cancer (CAC). Neohesperidin (NHP), a flavanone glycoside derived from citrus fruits, has been reported to have anti-inflammatory, antioxidant, and anticancer potential. However, the function of NHP on tumorigenesis has not been well understood. To investigate the …

Pathophysiology of Anal Cancer

Publication Year: 2025 Source: Surg Oncol Clin N Am PMID: 39547766

No Abstract

Quantitative assessment of ultrasound microvessel imaging in Crohn's disease: correlation with pathological inflammation

Publication Year: 2025 Source: Eur Radiol PMID: 39547980

No Abstract

Disparities in Vaccination Amongst Socially Vulnerable Patients with Inflammatory Bowel Disease

Publication Year: 2025 Source: Dig Dis Sci PMID: 39548038 DOI: 10.1007/s10620-024-08733-x

INTRODUCTION: Social determinants of health (SDOH) have a known impact on disparities in vaccination. Despite an increased risk for infection in patients with inflammatory bowel disease (IBD), SDOH and vaccination in this population have not been studied. Using census tract-level data from the Centers for Disease Control's social vulnerability index …

The Impact of Obesity on the Prevalence and Complications of Perianal Fistulas of Crohn's Disease

Publication Year: 2025 Source: Dig Dis Sci PMID: 39548039 DOI: 10.1007/s10620-024-08729-7

BACKGROUND: The incidence of obesity in patients with inflammatory bowel disease (IBD) is increasing and there are limited data on the impact of obesity on perianal fistulas in Crohn's disease (CD). AIMS: We aim to examine the relationship between obesity and the prevalence and complications of Crohn's perianal fistulas. METHODS: …

Syringin ameliorates dextran sulphate colitis via alteration oxidative stress, inflammation NF-κB signalling pathway and gut microbiota

Publication Year: 2025 Source: Basic Clin Pharmacol Toxicol PMID: 39548740

No Abstract

Anti-integrin αvβ6 autoantibody in primary sclerosing cholangitis: a Japanese nationwide study

Publication Year: 2025 Source: J Gastroenterol PMID: 39549066 DOI: 10.1007/s00535-024-02169-w

BACKGROUND: Although specific biomarkers for primary sclerosing cholangitis (PSC) are required, no such biomarkers have been identified. We previously reported that patients with PSC had anti-integrin alphavbeta6 autoantibodies at only two hospitals. In this study, we aimed to validate the accuracy of the autoantibodies in diagnosing PSC using the newly …

High Serum Pesticide Levels Are Associated With Increased Odds of Inflammatory Bowel Disease in a Nested Case-Control Study

Publication Year: 2025 Source: Gastroenterology PMID: 39549765

No Abstract

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