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Plasma calprotectin as a biomarker of inflammatory activity in ulcerative colitis

Publication Year: 2025 Source: Med Clin (Barc) PMID: 39550244 DOI: 10.1016/j.medcli.2024.09.009

BACKGROUND: An ideal test to evaluate the inflammatory burden in ulcerative colitis is still an unmet need. Fecal calprotectin (FCP) and C-reactive protein (CRP) have significant limitations. Plasma calprotectin (PC) seems to be promising in inflammatory diseases, but its value in IBD is still to be determined. Our aim was …

A review investigating delays in Crohn's disease diagnosis

Publication Year: 2025 Source: Clin Res Hepatol Gastroenterol PMID: 39551466

No Abstract

Revisional ileoanal pouch surgery with in situ pouch augmentation for recurrent pouch inlet stricture

Publication Year: 2025 Source: Colorectal Dis PMID: 39551960 DOI: 10.1111/codi.17241

No Abstract

Genomic prediction of heterosis, inbreeding control, and mate allocation in outbred diploid and tetraploid populations

Publication Year: 2025 Source: Genetics PMID: 39552210 DOI: 10.1093/genetics/iyae193

Breeders have long appreciated the need to balance selection for short-term genetic gain with maintaining genetic variance for long-term gain. For outbred populations, the method called optimum contribution selection (OCS) chooses parental contributions to maximize the average breeding value at a prescribed inbreeding rate. With optimum mate allocation (OMA), the …

Review Article: Green Management of IBD-New Paradigms for an Eco-Friendly Approach

Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39552383 DOI: 10.1111/apt.18399

BACKGROUND: The worldwide prevalence of inflammatory bowel disease (IBD) is increasing, with its potential evolution as a global disease and a consequent increase in its burden on healthcare systems. These estimates do not factor in the 'real' price of IBD, which, beyond curbing career aspirations, instilling social stigma, and impairing …

Subcutaneous Infliximab Concentration Thresholds for Mucosal and Transmural Healing in Patients With Crohn's Disease

Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39552401

No Abstract

Quality of bowel preparation for colonoscopy in patients on glucagon-like peptide-1 receptor agonists

Publication Year: 2025 Source: Gastrointest Endosc PMID: 39557200

No Abstract

Generation and validation of antibody 42B1 recognizing galactose-deficient IgG for diagnosis of chronic inflammatory diseases

Publication Year: 2025 Source: Clin Chim Acta PMID: 39557230 DOI: 10.1016/j.cca.2024.120052

Galactose-deficient (agalactosyl) IgG is significantly increased in the serum of patients with rheumatoid arthritis, and autoantibodies against it are used in clinical tests. Subsequent studies also show increased agalactosyl IgG in many chronic inflammatory diseases. In this study, we generated antibody 42B1 recognizing agalactosyl IgG and developed a new method …

Enhancing Gut Microbiome Research for Inflammatory Bowel Diseases Therapy: Addressing Study Limitations and Advancing Clinical Translation

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39557405

No Abstract

Editorial: Updated COVID-19 Boosters-Tailoring Protection for Patients With IBD. Authors' Reply

Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39560174 DOI: 10.1111/apt.18401

No Abstract

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