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Editorial: Is There a Role for Therapeutic Drug Monitoring of Subcutaneous Infliximab in Patients With Inflammatory Bowel Disease?
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39560181
No Abstract
Tight junction regulation, intestinal permeability, and mucosal immunity in gastrointestinal health and disease
Publication Year: 2025 Source: Curr Opin Gastroenterol PMID: 39560621 DOI: 10.1097/MOG.0000000000001066
PURPOSE OF REVIEW: The contributions of intestinal barrier loss, that is, increased permeability, to multiple disorders, including inflammatory bowel disease (IBD), have been a topic of speculation for many years, and the literature is replete with conclusions based on correlation and speculation. The goal of this article is to critically …
The importance of growth differentiation factor 15 and interleukin 6 serum levels in inflammatory bowel diseases
Publication Year: 2025 Source: J Physiol Biochem PMID: 39560915 DOI: 10.1007/s13105-024-01057-4
There are only scarce recent reports about the role of growth differentiation factor 15 (GDF-15) and some more data about interleukin-6 (IL-6) in inflammatory bowel diseases (IBD). We assessed GDF-15 and IL-6 serum levels in patients with IBD and associations with their characteristics. We included 122 and 71 stored samples …
Long-Term Course and Prognostic Factors in Pediatric Ulcerative Proctitis: A Multicenter Cohort Study
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39561101
BACKGROUND: Although ulcerative proctitis (UP) in children is considered relatively mild, some patients have proximal disease extension and require immunosuppressive treatment. We investigated clinical characteristics and course of refractory UP in a multicenter pediatric cohort. METHODS: Analyzing data obtained between 2013 and 2022 at 10 institutions specializing in pediatric inflammatory …
Sanguinarine chloride hydrate mitigates colitis symptoms in mice through the regulation of the intestinal microbiome and metabolism of short-chain fatty acids
Publication Year: 2025 Source: Biochim Biophys Acta Mol Basis Dis PMID: 39561858
No Abstract
Segmental Regulation of Intestinal Motility by Colitis and the Adaptive Immune System in the Mouse Ileum and Colon
Publication Year: 2025 Source: Am J Pathol PMID: 39561965 DOI: 10.1016/j.ajpath.2024.10.020
Gastrointestinal motility disturbances are a hallmark of inflammatory bowel disease (IBD); however, their mechanisms remain unclear. This study used a dextran sulfate sodium-induced colitis mouse model, deficient in mature B and T lymphocytes, to assess intestinal motility and the role of the adaptive immune system in health and IBD. In …
Faecal phageome transplantation alleviates intermittent intestinal inflammation in IBD and the timing of transplantation matters: a preclinical proof-of-concept study in mice
Publication Year: 2025 Source: Gut PMID: 39562050 DOI: 10.1136/gutjnl-2024-333598
No Abstract
Reviewing the audacity of elixirs of inflammatory bowel disease from mushroom β-glucans: The solved and unresolved
Publication Year: 2025 Source: Carbohydr Polym PMID: 39562106
No Abstract
Myocardial iron intake following intravenous iron therapy with ferric carboxymaltose is sustained at 1 year despite recurrence of iron deficiency
Publication Year: 2025 Source: Br J Haematol PMID: 39562805
No Abstract
Response to FDA draft guidance on pediatric IBD drug approval trials: A consensus statement from the IBD Porto Group
Publication Year: 2025 Source: J Pediatr Gastroenterol Nutr PMID: 39564649 DOI: 10.1002/jpn3.12395
No Abstract
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