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Baseline colitogenicity and acute perturbations of gut microbiota in immunotherapy-related colitis
Publication Year: 2025 Source: J Exp Med PMID: 39666007
No Abstract
Pimpinellin mitigates DSS-induced ulcerative colitis in mice by reducing inflammation and regulating gut microbiota
Publication Year: 2025 Source: Phytomedicine PMID: 39667138
No Abstract
Concurrent Fabry disease and IgA nephropathy in a patient with Crohn's disease: A case report
Publication Year: 2025 Source: Nephrology (Carlton) PMID: 39667372
We present a unique case of concurrent Fabry disease (FD) and IgA nephropathy (IgAN) in a 27-year-old female with a 10-year history of Crohn's disease (CD). The patient presented to the nephrology clinic with microscopic haematuria and proteinuria on routine tests. A kidney biopsy revealed mesangial matrix widening, mesangial cell …
Primary ad hoc tip-in mucosectomy for colitis-related erythema-like dysplasia (with video)
Publication Year: 2025 Source: Gastrointest Endosc PMID: 39667682 DOI: 10.1016/j.gie.2024.12.006
No Abstract
Exploring the promising potential of alcohol extract from the aerial part of dill in ameliorating DSS-induced ulcerative colitis in mice
Publication Year: 2025 Source: J Ethnopharmacol PMID: 39667686
No Abstract
Atractylodes macrocephala Koidz polysaccharide ameliorates DSS-induced colitis in mice by regulating the gut microbiota and tryptophan metabolism
Publication Year: 2025 Source: Br J Pharmacol PMID: 39667762
No Abstract
Early tumour necrosis factor antagonist treatment prevents perianal fistula development in children with Crohn's disease: post hoc analysis of the RISK study
Publication Year: 2025 Source: Gut PMID: 39667905
BACKGROUND: One in three children with Crohn's disease develop perianal fistula complications (PFCs), among the most disturbing and difficult-to-treat disease-related complications. Retrospective evidence suggests PFCs may be preventable. OBJECTIVE: We aimed to determine if early antitumour necrosis factor-alpha (anti-TNF⍺) therapy prevents PFC development in a well-characterised prospective cohort of paediatric …
Gut bacterial membrane components as pathogenic signalling molecules in PSC-IBD
Publication Year: 2025 Source: J Hepatol PMID: 39668012 DOI: 10.1016/j.jhep.2024.11.024
No Abstract
The impact of IBD on ability to work and study: a patient perspective
Publication Year: 2025 Source: Scand J Gastroenterol PMID: 39668756 DOI: 10.1080/00365521.2024.2440794
PURPOSE: The aim of this study was to explore the multifaceted ways in which inflammatory bowel disease (IBD) negatively affects working life and studies. MATERIAL AND METHODS: IBD patients were identified by diagnosis codes from the hospital records of a Finnish University Hospital. Patients were sent questionnaires via mail and …
Plasma protein-based and polygenic risk scores serve complementary roles in predicting inflammatory bowel disease
Publication Year: 2025 Source: Pac Symp Biocomput PMID: 39670393 DOI: 10.1142/9789819807024_0037
Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), has a significant genetic component and is increasingly prevalent due to environmental factors. Current polygenic risk scores (PRS) have limited predictive power and cannot inform time of symptom onset. Circulating proteomics profiling offers a novel, non-invasive approach for …
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