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Are early-life exposures associated with inflammatory bowel disease? A critique of a recent nested case-control study
Publication Year: 2025 Source: Dig Liver Dis PMID: 39672773
No Abstract
Biologic agents for IBD come of age as host-microbe interactions emerge
Publication Year: 2025 Source: Nat Rev Gastroenterol Hepatol PMID: 39672958 DOI: 10.1038/s41575-024-01029-5
No Abstract
Importance of rectal over colon status in ulcerative colitis remission: the role of microinflammation and mucosal barrier dysfunction in relapse
Publication Year: 2025 Source: J Gastroenterol PMID: 39672976
No Abstract
Genome-Wide DNA Methylation Identifies Potential Disease-Specific Biomarkers and Pathophysiologic Mechanisms in Irritable Bowel Syndrome, Inflammatory Bowel Disease, and Celiac Disease
Publication Year: 2025 Source: Neurogastroenterol Motil PMID: 39673136 DOI: 10.1111/nmo.14980
BACKGROUND AND AIMS: Irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and celiac disease (CeD) present with similar gastrointestinal (GI) symptoms. DNA methylation-based biomarkers have not been investigated as diagnostic biomarkers to classify these disorders. We aimed to study DNA methylation profiles of IBS, IBD, CeD, and healthy controls (HC), …
Arthralgia and Extraintestinal Manifestations in Crohn's Disease Elevate the Risk of IBD-Related Arthritis over Sacroiliitis
Publication Year: 2025 Source: Rheumatol Ther PMID: 39673666 DOI: 10.1007/s40744-024-00728-4
INTRODUCTION: Inflammatory bowel disease (IBD) related arthritis is the most prevalent extraintestinal manifestation (EIM) of IBD, ranging between 10 and 39%. Magnetic resonance enterography (MRE) is used to assess small bowel disease involvement in Crohn's disease (CD) and can detect signs of sacroiliitis in up to 23.5% of patients. The …
Open Label Vancomycin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Improved Colonic Disease Activity and Associations With Changes in Host-Microbiome-Metabolomic Signatures
Publication Year: 2025 Source: J Crohns Colitis PMID: 39673746 DOI: 10.1093/ecco-jcc/jjae189
BACKGROUND: We conducted a single-arm interventional study, to explore mucosal changes associated with clinical remission under oral vancomycin (OV) treatment, in primary sclerosing cholangitis-associated inflammatory bowel disease (PSC-IBD); NCT05376228. METHODS: Fifteen patients with PSC and active colitis (median fecal calprotectin 459 microg/g; median total Mayo score 5) were treated with …
Adhesive thermosensitive polydopamine hydrogel containing Mn(3)O(4) anchored halloysite clay for treatment of ulcerative colitis
Publication Year: 2025 Source: J Colloid Interface Sci PMID: 39673927
No Abstract
An online mindfulness-based intervention for adults with Inflammatory Bowel Disease & psychological distress: A feasibility randomized controlled trial of the Mind4IBD program
Publication Year: 2025 Source: J Psychosom Res PMID: 39674049 DOI: 10.1016/j.jpsychores.2024.111984
OBJECTIVE: The bidirectional relationship between disease activity and mental health in inflammatory bowel disease (IBD) has prompted investigations into the efficacy of psychotherapies, such as mindfulness-based interventions (MBI), for improving biopsychosocial outcomes. Therefore, the aim is to examine the feasibility, acceptability, and preliminary efficacy of an online-delivered, self-directed MBI, adapted …
Mesenteric sparing or extended resection in primary ileocolic resection for Crohn's disease
Publication Year: 2025 Source: Lancet Gastroenterol Hepatol PMID: 39674211
No Abstract
Mesenteric sparing or extended resection in primary ileocolic resection for Crohn's disease
Publication Year: 2025 Source: Lancet Gastroenterol Hepatol PMID: 39674213
No Abstract
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